Microbiome & Chronic Diseases

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Bifidobacteriaceae ⇒ Bifidobacterium {10000120}

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Anti-inflammatory, Anti-cancer



References Notes

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Shared Reference Notes

  • [1.123
    - Bifidobacterium can resist the antimicrobial activity of bile salts.
  • [1.124] [#Autism] [#Short Chain Fatty Acid
    - The reduction of Bifidobacterium also results in reduced levels of short-chain fatty acids (SCFAs), common in ASD children.
  • - Bifidobacterium can produce #GABA
  • [1.125] [#Cancer
    - Bifidobacterium is associated with antitumor effects, and oral administration of Bifidobacterium alone improved tumor control to the same degree as PD-L1 antibody therapy while combination treatment nearly abolished tumor growth in mice.
  • [1.110] [#Biliary tract cancer] [#Plant-based diet
    - High levels of plant dietary fibers in the gut resulted in proliferation of Bifidobacterium with anti-inflammatory and anti-tumor effects
  • [1.126
    - Bifidobacterium species decrease #Cancer cell proliferation via the inhibition of growth factor signaling as well as inducing mitochondrial-mediated apoptosis. - Bifidobacterium species reduce the adverse effects of chemo/immuno/radiation therapy by inhibiting proinflammatory cytokines.
  • [1.127] [#Diabetes Type 2
    - Bifidobacterium appears to be the most consistently supported by the literature genus containing microbes potentially protective against T2D
  • [1.128] [#Galactooligosaccharides & modified mogrosides Sweetener
    - Significant growth during the fermentation at 10 h of bacterial populations includes Bifidobacterium, #Bacteroides, #Enterococcus, and #Clostridium coccoides. - significant increase in production of SCFA in mMV-GOS at 10 h of fermentation, mainly seen in #Acetate and #Propionate production
  • [1.129
    - Bifidobacterium generate #GABA.
  • [1.107] [#Cancer] [#High salt diet
    - HSD increased the abundance of Bifidobacterium and caused increased gut permeability leading to intratumor localization of Bifidobacterium, which enhanced NK cell functions and tumor regression. - Intratumoral injections of Bifidobacterium activated NK cells, which inhibited tumor growth.
  • [1.130
    - Bifidobacterium breve have a positive correlation with acetic acid levels and intestinal epithelium expression of tight junction-related genes.
  • [1.108
    - Increased #Intake of anthocyanin-rich berries, for example, significantly increased abundance of Bifidobacterium
  • [1.131
    - “Bifidobacterium” pattern > increaseds #Sleep Activity at 12 months. - “Bifidobacterium” enterotype > infants with more nighttime awakenings.
  • [1.105] [#Exercise training
    - Exercise increases > increase α-diversity and microbial metabolites such as SCFAs. - Exercise > typically reveal increases in commensal taxa such as Bifidobacterium, #Lactobacilli, and #Akkermansia
  • [1.132] [#Lactoferrin
    - LF > iron donor to support the growth of some bacteria with lower iron demands > #Lactobacillus sp. or Bifidobacterium sp.
  • [1.114] [#Lachnospiraceae
    - 4 weeks of #Grape powder consumption > significantly increased the alpha diversity index of the gut microbiome > increasing #Verrucomicrobia at the phylum level, and a significant increase in #Akkermansia and increase in #Flavonifractor and Lachnospiraceae_UCG-010 > decrease in Bifidobacterium and #Dialister at the genus level.
  • [1.59] [#Chronic fatigue syndrome
    - MC/CFS > microbiome alterations that were consistent with an increased inflammation of the gut, namely significantly increased #Lactonifactor and #Alistipes - in particular an increase of #Alistipes and a decrease of butyrate-producer #Faecalibacterium were considered as top biomarkers with potential diagnostic value - abundance of Bifidobacterium and #Faecalibacterium to be reduced in the affected twin compared to the non-affected one. - Decreases in #Faecalibacterium and increases in #Coprobacillus were found. - Gut abundances of #Coprobacillus, of #Eggerthella and #Blautia were best able to distinguish patients from controls. - Decreases in #Faecalibacterium and increases in #Coprobacillus were found. - distinct microbial pattern with decreased anti-inflammatory #Firmicutes
  • [1.112
    - Barley contains abundant soluble #Beta-glucan fibers - Bifidobacterium, #Butyricicoccus, #Collinsella, #Ruminococcus 2, and #Dialister were characteristic candidate bacterias of the group that consumed large amounts of barley. - The relationship between #Barley consumption and Bifidobacterium remained after adjusting for disease and dietary habits, and that of #Butyricicoccus remained after adjusting for disease. - Network and cluster analyses revealed that #Barley consumption was directly correlated with Bifidobacterium and #Butyricicoccus.
  • [1.133
    - the abundance of oral Bifidobacterium was negatively associated with plasma concentrations of known #Covid-19 biomarkers interleukin 17F (IL-17F) and monocyte chemoattractant protein-1 (MCP-1)
  • [1.134] [#Obesity] [#Lactobacillus animalis
    - several bacteria such as: #Methanobrevibacter smithii, Bifidobacterium spp., Bifidobacterium animalis, #Escherichia coli, #Akkermansia muciniphila, #Anaerotruncus colihominis and bacteria of the Bacteroidetes strain have the capability to reduce the production of high-calorie substances and therefore also influence the caloric intake. A relatively low frequency of these bacteria correlates with increased body weight, as we have also observed.
  • [1.111] [#High-fiber diet
    - vegetables rich in #Inulin increased Bifidobacterium levels, promoted satiety, and reduced body weight
  • [1.135] [#Inflamatory bowel disease
    - studies have demonstrated striking differences between luminal and mucosal samples within the colon itself, specifically regarding mucosa-associated bacteria such as Bifidobacterium, #Lactobacillus, and #Akkermansia. - the microbial community composition is different between ileal luminal samples from colonic and fecal samples, as well along the length of the colon itself.
  • [1.136] [#Bifidobacterium breve
    - in pregnant women, Bifidobacterium represents a key beneficial microbiota genus, with levels observed to increase across #Pregnancy. - using germ-free and specific-pathogen-free mice, we demonstrate that the bacterium Bifidobacterium breve UCC2003 modulates maternal body adaptations, placental structure and nutrient transporter capacity, with implications for fetal metabolism and growth
  • [1.137] [#Inulin] [#Inulin Consumption
    - LCI is associated with an increase in Bifidobacterium.
  • [1.138
    - #Allicin (diallylthiosulfinate) is a natural food compound with multiple biological and pharmacological functions. - #Allicin treatment significantly improved GM composition and induced the most significant alteration enrichment of Bifidobacterium and #Lactobacillus. - #Allicin-induced GM to HFD mice (AGMT) significantly increased Blautia [short-chain fatty acids (SCFAs)-producing microbiota] and Bifidobacterium in HFD mice, also increased the SCFAs in the cecum,
  • [1.139] [#Inflamatory bowel disease, #Systemic anti-microbiota IgG
    - a modified high-throughput, culture-independent approach to quantify systemic IgG against gut commensal bacteria in human serum samples without the need for paired stool samples. - Using this approach, we highlight several commensal bacterial species that elicit elevated IgG responses in patients with inflammatory bowel disease (IBD) including taxa within the clades #Collinsella, Bifidobacterium, #Lachnospiraceae, and #Ruminococcaceae.
  • [1.140] [#Asthma] [#Children
    - low α-diversity and relative abundance of particular gut-commensal bacteria genera (Bifidobacterium, #Faecalibacterium, #Ruminococcus, and #Roseburia) are associated with childhood respiratory diseases.
  • [1.122
    - #Clostridium bartlettii and Bifidobacterium spp. produce ILA and IAA
  • [1.142] [#Bifidobacterium longum] [#Human milk oligosaccharides] [#Breast feeding
    - breast fed babies Bifidobacterium spp. is typically high, than in formula fed babies because Bifidobacterium longum utilizes fucosylated oligosaccharides which is present in mother’s milk.
  • [#High fibre plant protein-rich diet] - Bifidobacterium spp. was in direct correlation with intake of dietary protein such as vegetable protein and fibre specifically soluble one which are found in green vegetables like beans, broccoli, asparagus, peas and Brussels sprouts.
  • [1.104] [#Culinary herbs and spices
    - six of seven aqueous culinary spice extracts of oregano, ginger, rosemary, cinnamon, black pepper and cayenne pepper were able to promote the growth of Bifidobacterium spp. in vitro, whereas turmeric was not. - stimulation of #Lactobacillus spp. and inhibition of certain #Clostridium spp. by all seven spices. - increase in most #Clostridium spp. after turmeric and curcumin intervention in a human study.
  • - high consumption compared to low consumption of #Cocoa derived flavanols, significantly stimulated growth of Bifidobacterium spp. and #Lactobacillus spp.
  • [#Obesity] - #Acetic acid, a product of Bifidobacterium spp. known to function as an appetite suppressant, was found to be most abundant in the faeces of mice following #Ginger supplementation.
  • [1.143] [#Autism
    - The depletion of Bifidobacterium species has been reported widely in ASD. - #Bifidobacteria are SCFA producers, and “psychobiotics” , and they modulate the gut–brain signals via γ-aminobutyric acid (GABA) and #Glutamate metabolism. - Bifidobacterium have been reported to improve behavior and prevent #Depression-like behaviors in mice.
  • [#Autism] - lower levels of #Prevotella and Bifidobacterium may lead to reduced levels of #Folate production due to diminished #Folate-dependent remethylation in ASD
  • [1.27] [#Parkinson’s Disease
    - Bifidobacterium and #Lactobacillus species, which are common constituents of commercial probiotics, were more abundant in PD than NHC metagenomes.
  • [1.144] [#Alzheimer’s disease
    - AD > A positive correlation between the pro-inflammatory cytokines and Escherichia/Shigella (pro-inflammatory taxon) and a negative correlation with #Eubacterium rectale (anti-inflammatory taxon). - a decrease in #Firmicutes and Bifidobacterium and increased levels of #Proteobacteria, #Actinobacteria - a disputed frequency of #Bacteroidetes in various studies..

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