Roseburia ⇒ Roseburia intestinalis {10000245}

Shared Reference Notes

• [1.1] 
  - the abundance of Roseburia intestinalis is negatively correlated with the size of atherosclerotic lesions in the mouse model of #Atherosclerosis. - when Roseburia intestinalis was taken along with a high-fiber diet, aortic atherosclerotic plaques were reduced in size. This study suggests that the butyrate, a microbial metabolite, mediates these effects
• - The most prominent butyrogenic bacteria groups are #Faecalibacterium prausnitzii, #Butyrivibriocrossotus and Roseburia intestinalis which several studies have reported the depletion of these bacteria in atherosclerosis
• [1.2] 
  - Roseburia intestinalis specifically able to metabolize the indigestible glycans β-mannans found in #Nuts into #Butyrate
• [1.3] 
  - Roseburia intestinalis produces butyrate and flagellin to influence the balance of Treg and Th17 cells.
• [1.4] [#Parkinson’s Disease] 
  - At one end of the spectrum, #Bifidobacterium dentium was elevated by 7-fold, #Actinomyces oris by 6.5-fold, #Streptococcus mutans by 6-fold. At the other end of the spectrum, Roseburia intestinalis was reduced by 7.5-fold, and #Blautia wexlerae by 5-fold.
• [1.5] [#Anorexia nervosa] 
  - In AN, #Roseburia inulinivorans and Roseburia intestinalis were depleted
• [1.6] [#Mild Cognitive Impairment] 
  - the abundance of #Butyrate producing bacteria such as #Lachnospiraceae family, #Subdoligranulum sp., Roseburia intestinalis, and #Roseburia hominis were reduced in the gut of MCI participants compared to cognitively healthy controls.

References Notes