Blautia wexlerae ⇒ Blautia {10001360}

References Notes

Shared Reference Notes

• [1.5] 
  - The abundances of Blautia wexlerae were linked to high blood levels of metabolites associated with several chronic diseases.
• [1.1] [#Diabetes Type 2] [#Oral administration of Blautia wexlerae] 
  - Blautia genus, especially B. wexlerae, as a commensal bacterium that is inversely correlated with #Obesity and type 2 diabetes mellitus. - Oral administration of B. wexlerae to mice induce metabolic changes and anti-inflammatory effects that decrease both high-fat diet–induced #Obesity and diabetes. - The beneficial effects of B. wexlerae are correlated with unique amino-acid metabolism to produce S-adenosylmethionine, acetylcholine, and L-ornithine and carbohydrate metabolism resulting in the accumulation of amylopectin and production of succinate, lactate, and acetate, with simultaneous modification of the gut bacterial composition. - S-adenosylmethionine, acetylcholine, and L-ornithine have anti-inflammatory properties and modify aspects of host metabolism, such as lipid metabolism, indicating that these compounds are potential effector metabolites for controlling #Obesity and diabetes.