Disease
Microbiota ☳
Metabolome
Factor
Clostridiales ⇒ Blautia {10000258}
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Definition: Blautia
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Initialisation date: 2020-09-30
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Enzyme: [ ]
Function: [ ]
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[ ] Shared Reference Notes
[1.1 ] [#Diabetes Type 1 ] - In patients with type 1 diabetes, elevated Blautia abundance was observed and was correlated with increased IA-2 tyrosine phosphatase autoantibodies, important markers of autoimmunity.
[#Diabetes Type 1 ] - In patients with type 1 diabetes, elevated Blautia abundance was observed and was correlated with increased IA-2 #Tyrosine phosphatase autoantibodies, important markers of autoimmunity.
- Increased Blautia has also been seen in #Obesity , Alzheimer’s disease, nonalcoholic fatty liver disease, and #Multiple Sclerosis .
[#Posttreatment Lyme disease syndrome ] - Blautia species represented three of the five most important features for this classification, and the relative abundance was elevated in the PTLDS cohort compared to those in the healthy and ICU cohorts.
[1.2 ] - The proportions of Blautia and F. Prausnitzii and absolute numbers of Blautia and Bifidobacterium species in the gut microbiome are directly correlated with the clinical stage of #Breast cancer ].
- For instance, patients with stage 1 #Breast cancer ] had a lower number of gut Blautia sp. in comparison with the ones with stage grade 3
[1.3 ] - #Protein powder consumption > decrease in #Lachnospiraceae , #Roseburia , Blautia , Synergistales, #Coprococcus , #Lactobacillales , Bacilli, #Bifidobacterium longum and #Firmicutes .
- #Protein powder consumption > higher abundance of #Bacteroidetes .
[1.4 ] - Severe Covid > higher abundance of four microbial species (i.e., #Burkholderia contaminans , #Bacteroides nordii , #Bifidobacterium longum , and Blautia sp. CAG 257), six microbial pathways (e.g., glycolysis and fermentation), and 10 virulence genes > further associated with host immune response.
- The abundance of Bu. contaminans > associated with higher levels of inflammation biomarkers and lower levels of immune cells.
- human-origin proteins identified from both blood and fecal samples suggested gut barrier dysfunction in #Covid-19 patients.
- The circulating levels of #Lipopolysaccharide -binding protein increased in patients with severe illness > associated with circulating inflammation biomarkers and immune cells.
- proteins of disease-related bacteria (e.g., B. longum) were detectable in blood samples from patients.
[1.5 ] [#Psychogenic erectile dysfunction ] - Erectile dysfunction > no #Alloprevotella .
- Erectile dysfunction > increased #Streptococci and #Subdoligranulum
- Erectile dysfunction > decreased #Prevotella sp.9, Blautia , #Lachnospiraceae NK4A136 groups and #Roseburia .
[1.6 ] [#Chronic fatigue syndrome ] - MC/CFS > microbiome alterations that were consistent with an increased inflammation of the gut, namely significantly increased #Lactonifactor and #Alistipes
- in particular an increase of #Alistipes and a decrease of butyrate-producer #Faecalibacterium were considered as top biomarkers with potential diagnostic value
- abundance of #Bifidobacterium and #Faecalibacterium to be reduced in the affected twin compared to the non-affected one.
- Decreases in #Faecalibacterium and increases in #Coprobacillus were found.
- Gut abundances of #Coprobacillus , of #Eggerthella and Blautia were best able to distinguish patients from controls.
- Decreases in #Faecalibacterium and increases in #Coprobacillus were found.
- distinct microbial pattern with decreased anti-inflammatory #Firmicutes
[1.7 ] [#Infectious diarrhea ] - A drastic disappearance of obligate anaerobic gut commensals (Blautia , #Prevotella , #Faecalibacterium , #Lachnospiraceae , #Ruminococcaceae , etc.), leading to a depletion of associated metabolites such as #Short Chain Fatty Acid (SCFAs)
[1.8 ] [#Hypertension ] - Abundance of Blautia and #Odoribacter showed a negative correlation with high SBP
[1.9 ] [#Parkinson’s Disease ] - #Prevotellaceae (Prevotella), #Ruminococcaceae (#Faecalibacterium ), #Lachnospiraceae (Blautia , #Roseburia ) that produce SCFA and help in the synthesis of mucin to maintain the intestinal integrity are considerably lower in abundance in PD
[#Ulcerative Colitis ] [#Primary bile acids , #Secondary bile acids ] - colonic CD displayed a disease-severity-related association with #Bacteroides vulgatus .
- Compared to colonic CD, ileal CD profiles displayed increased primary and secondary bile acid levels and concomitant shifts in taxa with noted sensitivities such as #Faecalibacterium prausnitzii or affinities for bile acid-rich environments, including #Gammaproteobacteria and Blautia sp.
[1.11 ] [#Multiple Sclerosis ] [#Blautia wexlerae , #Erysipelotrichaceae CCMM ] - In both progressive MS and RRMS > increased #Clostridium bolteae , #Ruthenibacterium lactatiformans , and #Akkermansia and decreased Blautia wexlerae, #Dorea formicigenerans , and #Erysipelotrichaceae CCMM.
- Unique to progressive MS, has elevated Enterobacteriaceae and Clostridium g24 FCEY and decreased Blautia and #Agathobaculum .
[1.12 ] [#Infants , #Mother-infant ] - Maternal gut strains transmitted after the first 3 months of life included members of the genera #Eubacterium , #Roseburia , and Blautia .
[1.13 ] [#Polyphenols ] - Blautia sp. MRG-PMF1 metabolizes #Curcumin to produce demethylcurcumin and bisdemethylcurcumin through a demethylation reaction.
[1.14 ] [#Gastric bypass surgery ] - #Lactococcus , #Streptococcus , and #Granulicatella are #Lactate -producing microorganisms, whereas #Dorea and Blautia are #Lactate oxidizers
[1.15 ] [#Multiple Sclerosis ] [#Lipocalin-2 ] - bacteria thought to be beneficial for inflammatory bowel disease (IBD) such as #Anaerobutyricum , Blautia , and #Roseburia , were reduced in fecal Lcn-2-high MS patients.
[1.16 ] [#Crohn’s disease ] [#Clostridium cluster IV ] - #Roseburia , #Gemmiger , #Coprococcus , #Ruminococcus 2, #Butyricicoccus , #Dorea , #Fusicatenibacter , #Anaerostipes , Clostridium IV were enriched in the healthy controls.
- Blautia , Clostridium IV, #Coprococcus , #Dorea , #Fusicatenibacter continued to significantly decrease in early and advanced CD patients, and Escherichia/Shigella and Proteus continued to significantly increase.
- negative correlation between #Dorea , #Butyricicoccus , #Roseburia and gland reduce, #Roseburia and FC, #Butyricicoccus and goblet cells decreased, Parabacterodies and sex, Clostridium IV and CRP, #Dorea and ESR .
- positive correlation between Escherichia/Shigella and CRP, #Ruminococcus 2 and clinical symptoms.
[1.17 ] [#Diabetes Type 2 ] - The genus Blautia was one of the most represented genera in both groups enriched in group T2D.
- #Lachnoclostridium were more abundant in the microbiome profiles of diabetic patients.
- There are anomalies in the genera #Bacteroides and #Prevotella , both of which are increased in the T2D, both genera are #Propionate producers.
[1.18 ] - #Inulin > increase genera Blautia , #Anaerostipes , and #Bifidobacterium
[1.19 ] [#Systemic lupus erythematosus ] [#Flavonoid , #Polyphenols ] - dietary polyphenol as dihydrochalcones and flavanones affected the gut microbiome and ameliorated lupus disease activity.
- dietary flavones increased Blautia (family: Lachnospiraceae), and that often found in active lupus diseases.
[#Anorexia nervosa ] [#Clostridium bolteae , #Clostridium innocuum ] - In AN : #Erysipelatoclostridium ramosum , Blautia species CAG, and Enterocloster bolteae innocuum (#Clostridium ) were increased.
[1.21 ] [#Lachnospiraceae ] [#Cannabidiol ] - CBD treatment increased the abundance of beneficial bacteria, which include Lachnospiraceae_NK4A136 and Blautia in the gut.
[1.22 ] [#Behcet’s Disease ] - Depleted #Dorea , Blautia , #Coprococcus , #Erysipelotrichaceae and #Lachnospiraceae as well as enriched #Bilophila and #Stenotrophomonas were identified in BU patients.
[1.23 ] [#Olive ] - both the #Peanut oil and EVOO significantly increased the relative abundance of #Bifidobacterium and reduced Blautia levels and also had favorable effects on body weight, #Cholesterol levels, and insulin sensitivity.
[#Olive ] - EVOO has demonstrated antibacterial and bacteriostatic effects against bacteria such as those in the #Desulfovibrionaceae ,a family of opportunistic pathogens associated with #Obesity and inflammation, and Blautia spp., which positively correlates with visceral fat accumulation in Japanese men and women.
[1.24 ] [#Crohn’s disease ] - The microbiome risk score (MRS) model yielded a hazard ratio (HR) of 2.24 and temporal validity by capturing individuals that developed CD up to five years prior to disease onset. The five most important taxa contributing to the MRS included #Ruminococcus torques , Blautia , #Colidextribacter , an uncultured genus-level group from Oscillospiraceace, and #Roseburia .
[1.25 ] - delayed maturation of the gut microbiome (characterized by reduced relative abundance of the genera #Roseburia , #Dialister , #Prevotella , #Faecalibacterium and Blautia and increased abundance of #Enterococcus ), as well as reduced stool levels of #Butyrate by the age of 12 months, is associated with aberrant immune responses and an increased risk of #Asthma diagnosis by the age of 5 years
[1.26 ] [#Bacteroides-Prevotella group ] - only #Faecalibacterium , but not Blautia , #Anaerostipes , or #Megamonas , was significantly lower in the #Hypertension group
[1.27 ] [#Celiac Disease ] - #Bacillus subtilis LZU-GM was isolated from Pakistani traditional fermented sourdough and could degrade 73.7% of #Gluten in 24 h in vitro.
- The #Gluten degradation was 3-fold higher in the small intestine of the strain LZU-GM treated mice group.
- #Gluten -treated mice established positive antigliadin antibodies (AGA) in serum (IgA, IgG, and anti-TG2 antibodies) as compared to the strain LZU-GM treatment group.
- the number of IFN-γ, TNF-α, #IL-10 , and COX-2 cells decrease in the lamina propria of the strain LZU-GM treatment group.
- Microbial community bar plot analysis showed that #Lactobacillus , #Dubosiella , and #Enterococcus genera were restored and stabilized in the LZU-GM treatment group while Blautia and #Ruminococcus were found lower.
[1.28 ] [#Crohn’s disease ] [#Dorea longicatena , #Ruminococcus lactaris ] - ileocolonic resection (ICR) in CD patients > amples collected at time of surgery were enriched in #Proteobacteria and harbored high levels of unusual, bacteria such as #Streptococcus mitis , #Undibacterium oligocarboniphilum, #Sphingomonas melonis and #Gemella haemolysans
- 6 months after surgery samples had elevated proportions of anaerobic bacteria belonging to #Lachnospiraceae (#Clostridium nexile, Blautia wexlereae, #Dorea longicatena).
- Remission was characterized by increased levels of bacteria belonging to #Bacteroides , #Dorea , #Ruminococcus and #Dialister genera, whereas recurrence was associated with increased levels of #Gemmiger formicilis , #Enterococcus durans and #Ruminococcus lactaris.
[1.29 ] [#Bacteroides vulgatus ] [#carrot-derived rhamnogalacturonan I ] [#Carrot ] - cRG-I supplementation (already at an HED of 0.3 g/d) lowered interpersonal compositional differences due to the selective stimulation of taxa that were consistently present among human adults, including OTUs related to #Bacteroides dorei /vulgatus and #Bifidobacterium longum (suspected keystone species), #Bacteroides thetaiotaomicron , #Bifidobacterium adolescentis and #Butyrate -producing taxa such as Blautia sp., #Anaerobutyricum hallii , and #Faecalibacterium prausnitzii .
- Blautia , #Faecalibacterium , and #Dorea levels were consistently more abundant in 8-year-olds with #Allergy than in #Children without #Allergy .
- #Faecalibacterium abundance was correlated with IL-10 and FOXP3 mRNA levels.
[1.31 ] [#Obesity ] [#Western-style diet ] - in western populations, Blautia genus abundance is directly correlated with both BMI and visceral fat, but the inverse relationship is observed in studies in Japanese and Chinese populations where decreasing in relative abundance of Blautia in the gut microbiome, is associated with increased visceral fat
[1.32 ] [#Systemic lupus erythematosus ] [#Ruminococcus gnavus ] - Expansions of only the anaerobic commensal, Ruminococcus (blautia ) gnavus (RG) occurred at times of high-disease activity, and were detected in almost half of patients during lupus nephritis (LN) disease flares.
[1.33 ] - Blautia , Fecalibacterium, and #Dorea were found to be related to cognition function and could alleviate the inflammatory reaction in #Cirrhosis patients
[1.34 ] [#Depression , #Major depressive disorder ] - Blautia , #Bifidobacterium and #Coprococcus with higher relative abundance in the treatment effective group were related to the efficacy of SSRIs antidepressants.
[1.35 ] - pPobiotic supplementation during #Antibiotic Therapy has a protective effect on Blautia and #Roseburia spp. levels
- Blautia level has a tendency to normalize spontaneously after #Antibiotic Therapy .
[1.36 ] [#Crohn’s disease ] - CD patients had higher abundances of a #Ruminococcus taxon and strongly depleted in a Blautia ASV, and previous csDMARD therapy was associated with increased #Akkermansia .
[1.37 ] [#Parkinson’s Disease ] [#Short Chain Fatty Acid ] - Decreases of short-chain fatty acid-producing genera, #Fusicatenibacter , #Faecalibacterium , and Blautia , as well as an increase of mucin-degrading genus #Akkermansia , predicted accelerated disease progression.
[1.38 ] - patients with #Celiac Disease showed the abundance of #Streptococcus , #Lactobacillus , #Veillonella , and #Allisonella species, while the abundance of #Ruminococcus , #Faecalibacterium , Blautia , #Gemmiger , and #Anaerostipes was decreased.
[1.39 ] [#Metabolic Dysfunction-associated Steatohepatitis ] [#Ginger ] - GEO reduced the relative abundance of NASH-associated bacteria, including Blautia and #Tyzzerella , which are considered harmful.
[#Metabolic Dysfunction-associated Steatohepatitis ] [#Lipopolysaccharide ] - Blautia abundance increased in NASH patients and was positively correlated with LPS levels
[#Ulcerative Colitis ] [#Prevotella ] - Prevotella_7 and Blautia taxa abundance, as well as two metabolic pathways, might serve as a discriminating signature between north Indian UC patients with active disease and those in remission.
[1.41 ] - #HDL had a positive association with Elusimicrobium and #Ezakiella , whereas #Dorea and Blautia were negatively associated with #Glucose
[#Pulmonary tubercolosis , #Tuberculosis ] - The genera #Parabacteroides , #Bacteroides , #Lachnoclostridium , and #Fusobacterium were markedly enhanced in the PTB group, while #Roseburia , Blautia , unidentified #Ruminococcaceae , #Bifidobacterium , #Romboutsia , and #Fusicatenibacter were enhanced in the HC group.
[1.42 ] [#Bacteroides-Prevotella group , #Ruminococcus gauvreauii ] [#Keto diet ] - The abundance of Ruminococcus_gauvreauii_group, #Bacteroides , #Bifidobacterium , and Blautia significantly increased, whereas that of #Lactobacillus , #Romboutsia , #Facklamia , and #Turicibacter significantly declined in the KD group compared with the ND group.
[1.43 ] [#Parkinson’s Disease ] [#Roseomonas mucosa ] [#Short Chain Fatty Acid ] - #Constipation severity is significantly correlated with the decrease of Blautia and #Faecalibacterium , short chain fatty acids (SCFAs)-producing taxa that can exert positive effects on the intestinal mucosa and which are decreased in PD.
[1.44 ] [#Multiple Sclerosis ] - Individuals with relapsing-remitting MS have an abundance of #Mycoplasma , #Pseudomonas , #Faecalibacterium , #Haemophilus , #Anaerostipes , Blautia , and #Dorea , while #Bacteroides , #Prevotella , #Parabacteroides , and #Adlercreutzia are relatively less common.
[1.45 ] [#Primary immune thrombocytopenia ] - fecal bacteria such as #Actinomycetaceae , Blautia , #Streptococcus , and #Lactobacillus are enriched, whereas bacteria such as #Bacteroides are depleted in ITP patients.
[1.46 ] [#High Fat Diet ] - Blautia (e.g., ASV24) and #Bilophila (e.g., ASV37) which had been observed with increased abundance upon HFD feeding
[1.47 ] [#Juvenile idiopathic arthritis ] [#Blautia faecis ] - Blautia faecis was completely absent in ABIS JIA but occurred in half of controls; a reduced incidence of Blautia has been previously noted cross-sectionally.
[1.48 ] [#Fasting ] - RIF was associated with significant drops in the levels of seven genera at the end of Ramadan: Blautia , #Coprococcus , #Dorea , #Faecalicatena , #Fusicatenibacter , #Lachnoclostridium , and #Mediterraneibacter .
- Blautia was more abundant before Ramadan #Fasting .
[#Diabetes Type 2 ] - Blautia produces #Acetic acid and significantly correlates with host physiological dysfunctions, such as #Obesity , diabetes, and various inflammatory diseases.
- An increase in Blautia abundance may inhibit insulin signaling and prevent fat accumulation in adipocytes
[#Obesity ] - individuals with an overweight phenotype have increased levels of specific bacterial genera in the #Firmicutes phylum, including Blautia , #Coprococcus , and #Dorea
Intervention in Disease [ ]
Author: MetaBiom
Identifier: 10000258
URL: https://www.metabiom.org/microbiota/153/blautia
Keywords: Microbiome, Dysbiosis, Microbiota, Organism, Bacteria
Common References
[1.1 ] A Distinct Microbiome Signature in Posttreatment Lyme Disease Patients [2021] [Research] [mBio] [Journal] [80001737 ]
[1.2 ] Microbiome and Breast Cancer: New Role for an Ancient Population [2020] [Review] [Frontiers in Oncology] [Journal] [80001809 ]
[1.3 ] Fueling Gut Microbes: A Review of the Interaction between Diet, Exercise, and the Gut Microbiota in Athletes [2021] [Review] [Advances in Nutrition] [Journal] [80002173 ]
[1.4 ] Gut microbiome alterations and gut barrier dysfunction are associated with host immune homeostasis in COVID-19 patients [2022] [Study] [BMC Medicine] [Journal] [80002258 ]
[1.5 ] Correlation between gut microbiota diversity and psychogenic erectile dysfunction [2021] [Study] [Translational Andrology and Urology] [Journal] [80002269 ]
[1.6 ] The Gut Microbiome in Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS) [2022] [Review] [Frontiers in Immunology] [Journal] [80002273 ]
[1.7 ] Dynamic of the human gut microbiome under infectious diarrhea [2022] [Study] [Current Opinion in Microbiology] [Journal] [80002290 ]
[1.8 ] Critical Role of the Interaction Gut Microbiota – Sympathetic Nervous System in the Regulation of Blood Pressure [2019] [Study] [Frontiers in Physiology] [Journal] [80002367 ]
[1.9 ] Exploring the multifactorial aspects of Gut Microbiome in Parkinson’s Disease [2022] [Review] [Folia Microbiologica] [Journal] [80002403 ]
[1.10 ] Location-specific signatures of Crohn’s disease at a multi-omics scale [2022] [Study] [Microbiome] [Journal] [80002549 ]
[1.11 ] Gut Microbiome in Progressive Multiple Sclerosis [2021] [Study] [Annals of Neurology] [Journal] [80002606 ]
[1.12 ] Mobile genetic elements from the maternal microbiome shape infant gut microbial assembly and metabolism [2022] [Study] [Cell] [Journal] [80002657 ]
[1.13 ] The Interaction of Polyphenols and the Gut Microbiota in Neurodegenerative Diseases [2022] [Review] [Nutrients] [Journal] [80002666 ]
[1.14 ] Temporospatial shifts in the human gut microbiome and metabolome after gastric bypass surgery [2020] [Study] [npj Biofilms and Microbiomes] [Journal] [80002685 ]
[1.15 ] Fecal Lcn-2 level is a sensitive biological indicator for gut dysbiosis and intestinal inflammation in multiple sclerosis [2022] [Study] [Frontiers in Immunology] [Journal] [80002718 ]
[1.16 ] Gut microbiota in the early stage of Crohn’s disease has unique characteristics [2022] [Study] [Gut Pathogens] [Journal] [80002734 ]
[1.17 ] Variation of butyrate production in the gut microbiome in type 2 diabetes patients [2023] [Clinical study] [International Microbiology] [Journal] [80002763 ]
[1.18 ] An open label, non-randomized study assessing a prebiotic fiber intervention in a small cohort of Parkinson’s disease participants [2023] [Cohort study] [Nature communications] [Journal] [80002769 ]
[1.19 ] The Role of Diet in Influencing the Diversity of Gut Microbiome Related to Lupus Disease Activities: A Systematic Review [2022] [Review] [International Journal of Microbiology] [Journal] [80002819 ]
[1.20 ] The gut microbiota contributes to the pathogenesis of anorexia nervosa in humans and mice [2023] [Study] [Nature Microbiology] [Journal] [80002863 ]
[1.21 ] Multi-Omics Reveals the Effects of Cannabidiol on Gut Microbiota and Metabolic Phenotypes [2023] [Study] [Cannabis and Cannabinoid Research] [Journal] [80002891 ]
[1.22 ] Gut microbial signatures and their functions in Behcet’s uveitis and Vogt-Koyanagi-Harada disease [2023] [Journal of Autoimmunity] [Journal] [80002936 ]
[1.23 ] Extra-virgin olive oil and the gut-brain axis: influence on gut microbiota, mucosal immunity, and cardiometabolic and cognitive health [2021] [Study] [Nutrition Reviews] [Journal] [80002976 ]
[1.24 ] Gut Microbiome Composition is associated with future onset of Crohn’s Disease in Healthy First-Degree Relatives [Cohort study] [80002997 ]
[1.25 ] Gut microbiome immaturity and childhood acute lymphoblastic leukaemia [2023] [Review] [80003007 ]
[1.26 ] The association between gut microbiome and hypertension varies according to enterotypes: a Korean study [2023] [Cohort study] [Frontiers in Microbiomes] [Journal] [80003028 ]
[1.27 ] A gluten degrading probiotic Bacillus subtilis LZU-GM relieve adverse effect of gluten additive food and balances gut microbiota in mice [2023] [Food Research International] [Journal] [80003030 ]
[1.28 ] Alterations of gut microbiome following gastrointestinal surgical procedures and their potential complications [2023] [Review] [Frontiers in Cellular and Infection Microbiology] [Journal] [80003038 ]
[1.29 ] Carrot RG-I Reduces Interindividual Differences between 24 Adults through Consistent Effects on Gut Microbiota Composition and Function Ex Vivo [2023] [Study] [Nutrients] [Journal] [80003041 ]
[1.30 ] Alterations of nasal microbiome in eosinophilic chronic rhinosinusitis [2023] [Journal of Allergy and Clinical Immunology] [Journal] [80003049 ]
[1.31 ] Assessing the Performance of a Novel Stool-Based Microbiome Test That Predicts Response to First Line Immune Checkpoint Inhibitors in Multiple Cancer Types [2023] [Cohort study] [Cancers] [Journal] [80003055 ]
[1.32 ] Longitudinal gut microbiome analyses and blooms of pathogenic strains during lupus disease flares [2023] [Annals of the Rheumatic Diseases] [Journal] [80003069 ]
[1.33 ] Gut microbiota and its relation to inflammation in patients with bipolar depression: a cross-sectional study [2023] [Annals of General Psychiatry] [Journal] [80003100 ]
[1.34 ] Association analysis of gut microbiota and efficacy of SSRIs antidepressants in patients with major depressive disorder [2023] [Journal of Affective Disorders] [Journal] [80003112 ]
[1.35 ] Probiotic supplementation during antibiotic treatment is unjustified in maintaining the gut microbiome diversity: a systematic review and meta-analysis [2023] [80003119 ]
[1.36 ] Spondyloarthritis, acute anterior uveitis, and Crohn’s disease have both shared and distinct gut microbiota [2023] [Arthritis & Rheumatology] [Journal] [80003209 ]
[1.37 ] Short chain fatty acids-producing and mucin-degrading intestinal bacteria predict the progression of early Parkinson’s disease [2022] [npj parkinson's disease ] [Journal] [80003245 ]
[1.38 ] Microbiome Metabolites in Health and Disease [80003332 ]
[1.39 ] Ginger essential oil prevents NASH progression by blocking the NLRP3 inflammasome and remodeling the gut microbiota-LPS-TLR4 pathway [2023] [80003336 ]
[1.40 ] Enrichment of Lactic Acid-Producing Bacteria in the Fecal Microbiota of Patients with Ulcerative Colitis in North India [2023] [Advanced Gut & Microbiome Research] [Journal] [80003339 ]
[1.41 ] Host Microbiome in tuberculosis: Disease, treatment, and immunity perspectives [80003344 ]
[1.42 ] Ketogenic diet ameliorates attention deficit hyperactivity disorder in rats via regulating gut microbiota [2023] [PLOS ONE] [Journal] [80003382 ]
[1.43 ] Gut Microbiota: A Novel Therapeutic Target for Parkinson’s Disease [2022] [Frontiers in Immunology] [Journal] [80003405 ]
[1.44 ] Neuropsychiatric and Neurological Diseases in Relation to the Microbiota-Gut-Brain Axis: From Research to Clinical Care [2023] [Review] [80003409 ]
[1.45 ] Gut Microbiome and Metabolome Were Altered and Strongly Associated With Platelet Count in Adult Patients With Primary Immune Thrombocytopenia [2020] [Frontiers in Microbiology] [Journal] [80003463 ]
[1.46 ] Microbially produced vitamin B12 contributes to the lipid-lowering effect of silymarin [2023] [Nature communications] [Journal] [80003469 ]
[1.47 ] Infant gut microbiota and environment associate with juvenile idiopathic arthritis many years prior to disease onset, especially in genetically vulnerable children [2023] [EBioMedicine] [Journal] [80003477 ]
[1.48 ] Effects of Ramadan intermittent fasting on gut microbiome: is the diet key? [2023] [Frontiers in Microbiology] [Journal] [80003505 ]
[1.49 ] Specific changes in faecal microbiota are associated with familial mediterranean fever [2019] [Annals of the Rheumatic Diseases] [Journal] [80001097 ]
[1.50 ] Temporal and long-term gut microbiota variation in allergic disease: a prospective study from infancy to school age [2019] [Allergy] [Journal] [80001034 ]
[1.51 ] Gut microbiota alterations in Alzheimer’s Disease [2017] [Scientific Reports] [Journal] [80000621 ]
[1.52 ] Fecal microbiota in patients with ankylosing spondylitis: correlation with dietary factors and disease activity [2019] [Clinica Chimica Acta] [Journal] [80001054 ]
[1.53 ] Sex-specific associations of infants’ gut microbiome with arsenic exposure in a US population [2018] [Scientific Reports] [Journal] [80000820 ]
[1.54 ] The fecal, oral, and skin microbiota of children with Chagas disease treated with benznidazole [2019] [PLOS ONE] [Journal] [80001023 ]
[1.55 ] Structural changes in the gut microbiome of constipated patients [2014] [Physiological genomics] [Journal] [80000505 ]
[1.56 ] A comparative study of the gut microbiota in immune-mediated inflammatory diseases - does a common dysbiosis exist? [2018] [Microbiome] [Journal] [80000942 ]
[1.57 ] Disrupted progression of the intestinal microbiota with age in children with cystic fibrosis [2016] [Scientific Reports] [Journal] [80000388 ]
[1.58 ] Imbalance of fecal microbiota at newly diagnosed type 1 diabetes in chinese children [2016] [Chinese Medical Journal] [Journal] [80000417 ]
[1.59 ] Alterations of the gut microbiota in Hashimoto’s Thyroiditis patients [2018] [Thyroid] [Journal] [80000751 ]
[1.60 ] Alterations to the lung microbiome in idiopathic pulmonary fibrosis patients [2019] [Frontiers in Cellular and Infection Microbiology] [Journal] [80001134 ]
[1.61 ] Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome. [2011] [Gastroenterology] [Journal] [80000294 ]
[1.62 ] Characterization of the gut microbiota of Kawasaki disease patients by metagenomic analysis [2015] [Frontiers in Microbiology] [Journal] [80000556 ]
[1.63 ] Altered fecal microbiota composition in patients with major depressive disorder. [2015] [Brain, Behavior, and Immunity] [Journal] [80000265 ]
[1.64 ] Gut microbiota profiling of pediatric nonalcoholic fatty liver disease and obese patients unveiled by an integrated meta-omics-based approach [2017] [Hepatology] [Journal] [80000626 ]
[1.65 ] Gut microbiome of treatment-naïve MS patients of different ethnicities early in disease course [2019] [Scientific Reports] [Journal] [80001262 ]
[1.66 ] Gut microbiota and endothelial dysfunction markers in obese Mexican children and adolescents [2018] [Nutrients] [Journal] [80001006 ]
[1.67 ] Diversity analysis of gut microbiota in osteoporosis and osteopenia patients [2017] [PeerJ] [Journal] [80001198 ]
[1.68 ] Gut microbiota altered in mild cognitive impairment compared with normal cognition in sporadic Parkinson’s disease [2020] [Frontiers in Neurology] [Journal] [80001370 ]
[1.69 ] Early-onset preeclampsia is associated with gut microbial alterations in antepartum and postpartum women [2019] [Frontiers in Cellular and Infection Microbiology] [Journal] [80001138 ]
[1.70 ] Gut microbiota dysbiosis in a cohort of patients with psoriasis [2019] [British Journal of Dermatology] [Journal] [80001039 ]
[1.71 ] Altered gut microbiota in Rett syndrome [2016] [Microbiome] [Journal] [80000534 ]
[1.72 ] Analysis of gut mycobiota in first-episode, drug-naïve Chinese patients with schizophrenia: a pilot study [2020] [Behavioural Brain Research] [Journal] [80001250 ]
[1.73 ] Altered mucosal microbiome diversity and disease severity in Sjögren Syndrome [2016] [Scientific Reports] [Journal] [80000347 ]
[1.74 ] Gut microbiota dysbiosis in male patients with chronic traumatic complete spinal cord injury [2018] [Journal of Translational Medicine] [Journal] [80000938 ]
[1.75 ] Comparison of the ocular microbiome between chronic Stevens-Johnson syndrome patients and healthy subjects [2020] [Scientific Reports] [Journal] [80001339 ]
[1.76 ] Alterations in the gut microbiota and metabolite profiles of thyroid carcinoma patients [2019] [International Journal of Cancer] [Journal] [80000975 ]
[1.77 ] Analysis of endoscopic brush samples identified mucosa-associated dysbiosis in inflammatory bowel disease [2018] [Journal of Gastroenterology] [Journal] [80000679 ]
[1.78 ] Characteristics of fecal and mucosa-associated microbiota in Chinese patients with inflammatory bowel disease [2014] [Medicine] [Journal] [80000665 ]
[1.79 ] Patients with acne vulgaris have a distinct gut microbiota in comparison with healthy controls [2018] [Acta Dermato-Venereologica] [Journal] [80000937 ]
[1.80 ] Alterations in the gut microbiota of patients with acquired immune deficiency syndrome [2018] [Journal of Cellular and Molecular Medicine] [Journal] [80000714 ]
[1.81 ] Changes in intestinal microflora in digestive tract diseases during pregnancy [2020] [Archives of Gyneacology and Obstetrics] [Journal] [80001321 ]
[1.82 ] Gut microbiota compositional and functional fingerprint in patients with alcohol use disorder and alcohol-associated liver disease [2020] [Liver International] [Journal] [80001386 ]
[1.83 ] Altered microbiomes distinguish Alzheimer’s disease from amnestic mild cognitive impairment and health in a Chinese cohort [2019] [Brain, Behavior, and Immunity] [Journal] [80001073 ]
[1.84 ] Gut microbiota profile in children affected by atopic dermatitis and evaluation of intestinal persistence of a probiotic mixture [2019] [Scientific Reports] [Journal] [80000949 ]
[1.85 ] Gut microbiota features in young children with autism spectrum disorders [2018] [Frontiers in Microbiology] [Journal] [80000980 ]
[1.86 ] Gut microbial profile in biliary atresia: a case-control study [2019] [Journal of Gastroenterology and Hepatology] [Journal] [80001225 ]
[1.87 ] The intestinal microbiota associated with cardiac valve calcification differs from that of coronary artery disease [2019] [Atherosclerosis] [Journal] [80000915 ]
[1.88 ] Comparison of small gut and whole gut microbiota of first-degree relatives with adult celiac disease patients and controls [2019] [Frontiers in Microbiology] [Journal] [80000986 ]
[1.89 ] Alterations of gut microbiota in cholestatic infants and their correlation with hepatic function [2018] [Frontiers in Microbiology] [Journal] [80000981 ]
[1.90 ] Characterization of intestinal microbiota in alcoholic patients with and without alcoholic hepatitis or chronic alcoholic pancreatitis [2018] [Scientific Reports] [Journal] [80000689 ]
[1.91 ] Modulation of the fecal bile acid profile by gut microbiota in cirrhosis [2013] [Journal of Hepatology] [Journal] [80000580 ]
[1.92 ] Human intestinal lumen and mucosa-associated microbiota in patients with colorectal cancer [2012] [PLOS ONE] [Journal] [80000305 ]
[1.93 ] Gut mucosal microbiome across stages of colorectal carcinogenesis [2015] [Nature communications] [Journal] [80000724 ]
[1.94 ] Gut microbiome-based diagnostic model to predict coronary artery disease [2020] [Journal of Agricultural and Food Chemistry] [Journal] [80001414 ]
[1.95 ] Alterations in gut microbiota of patients with COVID-19 during time of hospitalization [2020] [Gastroenterology] [Journal] [80001420 ]
[1.96 ] Altered gut microbiota is present in newly diagnosed pediatric patients with inflammatory bowel disease [2020] [Journal of Paediatric Gastroenterology and Nutrition] [Journal] [80001299 ]
[1.97 ] Fungal dysbiosis in mucosa-associated microbiota of Crohn’s disease patients [2016] [Journal of Crohn's and Colitis] [Journal] [80000760 ]
[1.98 ] Impact of cystic fibrosis disease on archaea and bacteria composition of gut microbiota_DUBLICATE [2017] [FEMS Microbiology Ecology] [Journal] [80000628 ]
[1.99 ] Hepatic glycogen storage diseases are associated to microbial dysbiosis [2019] [PLOS ONE] [Journal] [80001020 ]
[1.100 ] Alterations in the intestinal microbiota of patients with severe and active Graves’ orbitopathy: a cross-sectional study [2019] [Journal of Endocrinological Investigation] [Journal] [80000930 ]
[1.101 ] Alterations of the gut microbiota in patients with COVID-19 or H1N1 Influenza [2020] [Clinical Infectious Diseases] [Journal] [80001419 ]
[1.102 ] A compositional look at the human gastrointestinal microbiome and immune activation parameters in HIV infected subjects. [2014] [PLOS ONE] [Journal] [80000332 ]
[1.103 ] An altered intestinal mucosal microbiome in HIV-1 infection is associated with mucosal and systemic immune activation and endotoxemia. [2014] [Mucosal Immunology] [Journal] [80000343 ]
[1.104 ] Gut microbiota dysbiosis contributes to the development of hypertension [2017] [Review] [Microbiome] [Journal] [80000033 ]
[1.105 ] The gut microbiome in epilepsy [2020] [Microbial Pathogenesis] [Journal] [80001252 ]
[1.106 ] Fungal microbiota dysbiosis in IBD [2017] [Gut] [Journal] [80000756 ]
[1.107 ] Characteristic dysbiosis of gut microbiota of Chinese patients with diarrhea-predominant irritable bowel syndrome by an insight into the pan-microbiome [2019] [Chinese Medical Journal] [Journal] [80001123 ]
[1.108 ] Microbiome analytics of the gut microbiota in patients with juvenile idiopathic arthritis: a longitudinal observational cohort study [2019] [Arthritis & Rheumatology] [Journal] [80001040 ]
[1.109 ] Landscapes of bacterial and metabolic signatures and their interaction in major depressive disorders [2020] [Research] [Advanced Science] [Journal] [80001465 ]
[1.110 ] Nonalcoholic fatty liver disease is associated with dysbiosis independent of body mass index and insulin resistance [2018] [Scientific Reports] [Journal] [80000685 ]
[1.111 ] Characterization of gut microbiomes in nonalcoholic steatohepatitis (NASH) patients: a connection between endogenous alcohol and NASH [2013] [Hepatology] [Journal] [80000566 ]
[1.112 ] Multiple sclerosis patients have a distinct gut microbiota compared to healthy controls_DUBLICATE [2016] [Scientific Reports] [Journal] [80000891 ]
[1.113 ] Gut microbiome of multiple sclerosis patients and paired household healthy controls reveal associations with disease risk and course [2022] [Study] [Cell] [Journal] [80002601 ]
[1.114 ] Alterations of the gut microbiota in multiple system atrophy patients [2019] [Frontiers in Neuroscience] [Journal] [80001371 ]
[1.115 ] Dysbiosis of gut microbiota in patients with neuromyelitis optica spectrum disorders: a cross sectional study [2020] [Journal of Neuroimmunology] [Journal] [80001254 ]
[1.116 ] Gut microbial profile analysis by MiSeq sequencing of pancreatic carcinoma patients in China [2017] [Oncotarget] [Journal] [80000728 ]
[1.117 ] Gut microbiota dysbiosis worsens the severity of acute pancreatitis in patients and mice. [2019] [Journal of Gastroenterology] [Journal] [80001237 ]
[1.118 ] Colonic bacterial composition in Parkinson’s Disease [2015] [Movement Disorders] [Journal] [80000275 ]
[1.119 ] Inflammatory microbes and genes as potential biomarkers of Parkinson’s disease [2022] [Review] [npj Biofilms and Microbiomes] [Journal] [80002678 ]
[1.120 ] Metagenomics of Parkinson’s disease implicates the gut microbiome in multiple disease mechanisms [2022] [Cohort study] [Nature communications] [Journal] [80002696 ]
[1.121 ] Comprehensive analysis of serum and fecal bile acid profiles and interaction with gut microbiota in primary biliary cholangitis [2019] [Clinical Reviews in Allergy & Immunology] [Journal] [80000962 ]
[1.122 ] The gut microbiota, bile acids and their correlation in primary sclerosing cholangitis associated with inflammatory bowel disease [2018] [United European Gastroenterology Journal] [Journal] [80000678 ]
[1.123 ] Fungi participate in the dysbiosis of gut microbiota in patients with primary sclerosing cholangitis [2019] [Gut] [Journal] [80000990 ]
[1.124 ] Gut microbial dysbiosis is associated with development and progression of radiation enteritis during pelvic radiotherapy [2019] [Journal of Cellular and Molecular Medicine] [Journal] [80001170 ]
[1.125 ] Gut microbiota perturbations in reactive arthritis and postinfectious spondyloarthritis [2018] [Arthritis & Reumatology] [Journal] [80000722 ]
[1.126 ] Alterations of gut microbiome in the patients with severe fever with thrombocytopenia syndrome [2018] [Frontiers in Microbiology] [Journal] [80000848 ]
[1.127 ] Fecal microbiota signatures of adult patients with different types of short bowel syndrome [2017] [Journal of Gastroenterology and Hepatology] [Journal] [80000662 ]
[1.128 ] Alterations in the gut microbiota of patients with silica-induced pulmonary fibrosis [2019] [Journal of Occupational Medicine and Toxicology] [Journal] [80000939 ]
[1.129 ] Gut dysbiosis is prevailing in Sjögren’s syndrome and is related to dry eye severity [2020] [PLOS ONE] [Journal] [80001403 ]
[1.130 ] Dysbiosis of gut microbiota and short-chain fatty acids in acute ischemic stroke and the subsequent risk for poor functional outcomes [2020] [Research] [Journal of Parenteral and Enteral Nutrition] [Journal] [80001423 ]
[1.131 ] A single species of Clostridium subcluster XIVa decreased in ulcerative colitits patients [2016] [Inflammatory Bowel Diseases] [Journal] [80000620 ]
[1.132 ] Gut microbiota composition and fecal metabolic phenotype in patients with acute anterior uveitis [2018] [Investigative Opthalmology & Visual Science] [Journal] [80001190 ]
[1.133 ] Altered gut microbiome composition by appendectomy contributes to colorectal cancer [2022] [Study] [Oncogene] [Journal] [80002674 ]
[1.134 ] Beneficial reconstitution of gut microbiota and control of alpha-synuclein and curli-amyloids-producing enterobacteria, by beta 1,3-1,6 glucans in a clinical pilot study of autism and potentials in neurodegenerative diseases [2021] [Study] [medRXiv] [Journal] [80002371 ]