Disease
Microbiota ☳
Metabolome
Factor
Clostridiales ⇒ Blautia {10000258}
Record Keys
Parent:
Definition: Blautia
Details
Initialisation date: 2020-09-30
Meta Information
Rank:
Domain:
Zone: [ ]
Enzyme: [ ]
Function: [ ]
Notes: Shared Reference Notes
[1.1 ] [#Diabetes Type 1 ] Blautia abundance was observed and was correlated with increased IA-2 tyrosine phosphatase autoantibodies, important markers of autoimmunity.
[1.2 ] Blautia and F. Prausnitzii and absolute numbers of Blautia and Bifidobacterium species in the gut microbiome are directly correlated with the clinical stage of #Breast cancer ].
- For instance, patients with stage 1 #Breast cancer ] had a lower number of gut Blautia sp. in comparison with the ones with stage grade 3
[1.3 ] #Protein powder consumption > decrease in #Lachnospiraceae , #Roseburia , Blautia , Synergistales, #Coprococcus , #Lactobacillales , Bacilli, #Bifidobacterium longum and #Firmicutes .
- #Protein powder consumption > higher abundance of #Bacteroidetes .
[1.4 ] #Burkholderia contaminans , #Bacteroides nordii , #Bifidobacterium longum , and Blautia sp. CAG 257), six microbial pathways (e.g., glycolysis and fermentation), and 10 virulence genes > further associated with host immune response.
- The abundance of Bu. contaminans > associated with higher levels of inflammation biomarkers and lower levels of immune cells.
- human-origin proteins identified from both blood and fecal samples suggested gut barrier dysfunction in #Covid-19 patients.
- The circulating levels of #Lipopolysaccharide -binding protein increased in patients with severe illness > associated with circulating inflammation biomarkers and immune cells.
- proteins of disease-related bacteria (e.g., B. longum) were detectable in blood samples from patients.
[1.5 ] [#Psychogenic erectile dysfunction ] #Alloprevotella .
- Erectile dysfunction > increased #Streptococci and #Subdoligranulum
- Erectile dysfunction > decreased #Prevotella sp.9, Blautia , #Lachnospiraceae NK4A136 groups and #Roseburia .
[1.6 ] [#Chronic fatigue syndrome ] #Lactonifactor and #Alistipes
- in particular an increase of #Alistipes and a decrease of butyrate-producer #Faecalibacterium were considered as top biomarkers with potential diagnostic value
- abundance of #Bifidobacterium and #Faecalibacterium to be reduced in the affected twin compared to the non-affected one.
- Decreases in #Faecalibacterium and increases in #Coprobacillus were found.
- Gut abundances of #Coprobacillus , of #Eggerthella and Blautia were best able to distinguish patients from controls.
- Decreases in #Faecalibacterium and increases in #Coprobacillus were found.
- distinct microbial pattern with decreased anti-inflammatory #Firmicutes
[1.7 ] [#Infectious diarrhea ] Blautia , #Prevotella , #Faecalibacterium , #Lachnospiraceae , #Ruminococcaceae , etc.), leading to a depletion of associated metabolites such as #Short Chain Fatty Acid (SCFAs)
[1.8 ] [#Hypertension ] Blautia and #Odoribacter showed a negative correlation with high SBP
[1.9 ] [#Parkinson’s Disease ] #Prevotellaceae (Prevotella), #Ruminococcaceae (#Faecalibacterium ), #Lachnospiraceae (Blautia , #Roseburia ) that produce SCFA and help in the synthesis of mucin to maintain the intestinal integrity are considerably lower in abundance in PD
[#Ulcerative Colitis ] [#Primary bile acids , #Secondary bile acids ] - colonic CD displayed a disease-severity-related association with #Bacteroides vulgatus .
- Compared to colonic CD, ileal CD profiles displayed increased primary and secondary bile acid levels and concomitant shifts in taxa with noted sensitivities such as #Faecalibacterium prausnitzii or affinities for bile acid-rich environments, including #Gammaproteobacteria and Blautia sp.
[1.11 ] [#Multiple Sclerosis ] [#Blautia wexlerae , #Erysipelotrichaceae CCMM ] #Clostridium bolteae , #Ruthenibacterium lactatiformans , and #Akkermansia and decreased Blautia wexlerae, #Dorea formicigenerans , and #Erysipelotrichaceae CCMM.
- Unique to progressive MS, has elevated Enterobacteriaceae and Clostridium g24 FCEY and decreased Blautia and #Agathobaculum .
[1.12 ] [#Infants , #Mother-infant ] #Eubacterium , #Roseburia , and Blautia .
[1.13 ] [#Polyphenol ] Blautia sp. MRG-PMF1 metabolizes #Curcumin to produce demethylcurcumin and bisdemethylcurcumin through a demethylation reaction.
[1.14 ] [#Gastric bypass surgery ] #Lactococcus , #Streptococcus , and #Granulicatella are #Lactate -producing microorganisms, whereas #Dorea and Blautia are #Lactate oxidizers
[1.15 ] [#Multiple Sclerosis ] [#Lipocalin-2 ] #Anaerobutyricum , Blautia , and #Roseburia , were reduced in fecal Lcn-2-high MS patients.
[1.16 ] [#Crohn’s disease ] [#Clostridium cluster IV ] #Roseburia , #Gemmiger , #Coprococcus , #Ruminococcus 2, #Butyricicoccus , #Dorea , #Fusicatenibacter , #Anaerostipes , Clostridium IV were enriched in the healthy controls.
- Blautia , Clostridium IV, #Coprococcus , #Dorea , #Fusicatenibacter continued to significantly decrease in early and advanced CD patients, and Escherichia/Shigella and Proteus continued to significantly increase.
- negative correlation between #Dorea , #Butyricicoccus , #Roseburia and gland reduce, #Roseburia and FC, #Butyricicoccus and goblet cells decreased, Parabacterodies and sex, Clostridium IV and CRP, #Dorea and ESR .
- positive correlation between Escherichia/Shigella and CRP, #Ruminococcus 2 and clinical symptoms.
[1.17 ] [#Diabetes Type 2 ] Blautia was one of the most represented genera in both groups enriched in group T2D.
- #Lachnoclostridium were more abundant in the microbiome profiles of diabetic patients.
- There are anomalies in the genera #Bacteroides and #Prevotella , both of which are increased in the T2D, both genera are #Propionate producers.
[1.18 ] #Inulin > increase genera Blautia , #Anaerostipes , and #Bifidobacterium
[1.19 ] [#Systemic lupus erythematosus ] [#Flavonoid ] #Polyphenol as dihydrochalcones and flavanones affected the gut microbiome and ameliorated lupus disease activity.
- dietary flavones increased Blautia (family: Lachnospiraceae), and that often found in active lupus diseases.
[#Anorexia nervosa ] [#Clostridium bolteae , #Clostridium innocuum ] - In AN : #Erysipelatoclostridium ramosum , Blautia species CAG, and Enterocloster bolteae innocuum (#Clostridium ) were increased.
[1.21 ] [#Lachnospiraceae ] [#Cannabidiol ] Blautia in the gut.
[1.22 ] [#Behcet’s Disease ] #Dorea , Blautia , #Coprococcus , #Erysipelotrichaceae and #Lachnospiraceae as well as enriched #Bilophila and #Stenotrophomonas were identified in BU patients.
[1.23 ] [#Olive ] #Peanut oil and EVOO significantly increased the relative abundance of #Bifidobacterium and reduced Blautia levels and also had favorable effects on body weight, #Cholesterol levels, and insulin sensitivity.
[#Olive ] - EVOO has demonstrated antibacterial and bacteriostatic effects against bacteria such as those in the #Desulfovibrionaceae ,a family of opportunistic pathogens associated with #Obesity and inflammation, and Blautia spp., which positively correlates with visceral fat accumulation in Japanese men and women.
Author: MetaBiomIdentifier: 10000258URL: https://www.metabiom.org/microbiota/153/blautiaKeywords: Microbiome, Dysbiosis, Microbiota, Organism, Bacteria
Common References
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[1.2 ] Microbiome and Breast Cancer: New Role for an Ancient Population 80001809 ]
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[1.4 ] Gut microbiome alterations and gut barrier dysfunction are associated with host immune homeostasis in COVID-19 patients 80002258 ]
[1.5 ] Correlation between gut microbiota diversity and psychogenic erectile dysfunction 80002269 ]
[1.6 ] The Gut Microbiome in Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS) 80002273 ]
[1.7 ] Dynamic of the human gut microbiome under infectious diarrhea 80002290 ]
[1.8 ] Critical Role of the Interaction Gut Microbiota – Sympathetic Nervous System in the Regulation of Blood Pressure 80002367 ]
[1.9 ] Exploring the multifactorial aspects of Gut Microbiome in Parkinson’s Disease 80002403 ]
[1.10 ] Location-specific signatures of Crohn’s disease at a multi-omics scale 80002549 ]
[1.11 ] Gut Microbiome in Progressive Multiple Sclerosis 80002606 ]
[1.12 ] Mobile genetic elements from the maternal microbiome shape infant gut microbial assembly and metabolism 80002657 ]
[1.13 ] The Interaction of Polyphenols and the Gut Microbiota in Neurodegenerative Diseases 80002666 ]
[1.14 ] Temporospatial shifts in the human gut microbiome and metabolome after gastric bypass surgery 80002685 ]
[1.15 ] Fecal Lcn-2 level is a sensitive biological indicator for gut dysbiosis and intestinal inflammation in multiple sclerosis 80002718 ]
[1.16 ] Gut microbiota in the early stage of Crohn’s disease has unique characteristics 80002734 ]
[1.17 ] Variation of butyrate production in the gut microbiome in type 2 diabetes patients 80002763 ]
[1.18 ] An open label, non-randomized study assessing a prebiotic fiber intervention in a small cohort of Parkinson’s disease participants 80002769 ]
[1.19 ] The Role of Diet in Influencing the Diversity of Gut Microbiome Related to Lupus Disease Activities: A Systematic Review 80002819 ]
[1.20 ] The gut microbiota contributes to the pathogenesis of anorexia nervosa in humans and mice 80002863 ]
[1.21 ] Multi-Omics Reveals the Effects of Cannabidiol on Gut Microbiota and Metabolic Phenotypes 80002891 ]
[1.22 ] Gut microbial signatures and their functions in Behcet’s uveitis and Vogt-Koyanagi-Harada disease 80002936 ]
[1.23 ] Extra-virgin olive oil and the gut-brain axis: influence on gut microbiota, mucosal immunity, and cardiometabolic and cognitive health 80002976 ]
[1.24 ] Specific changes in faecal microbiota are associated with familial mediterranean fever 80001097 ]
[1.25 ] Temporal and long-term gut microbiota variation in allergic disease: a prospective study from infancy to school age 80001034 ]
[1.26 ] Gut microbiota alterations in Alzheimer’s Disease 80000621 ]
[1.27 ] Fecal microbiota in patients with ankylosing spondylitis: correlation with dietary factors and disease activity 80001054 ]
[1.28 ] Sex-specific associations of infants’ gut microbiome with arsenic exposure in a US population 80000820 ]
[1.29 ] The fecal, oral, and skin microbiota of children with Chagas disease treated with benznidazole 80001023 ]
[1.30 ] Structural changes in the gut microbiome of constipated patients 80000505 ]
[1.31 ] A comparative study of the gut microbiota in immune-mediated inflammatory diseases - does a common dysbiosis exist? 80000942 ]
[1.32 ] Disrupted progression of the intestinal microbiota with age in children with cystic fibrosis 80000388 ]
[1.33 ] Imbalance of fecal microbiota at newly diagnosed type 1 diabetes in chinese children 80000417 ]
[1.34 ] Alterations of the gut microbiota in Hashimoto’s Thyroiditis patients 80000751 ]
[1.35 ] Alterations to the lung microbiome in idiopathic pulmonary fibrosis patients 80001134 ]
[1.36 ] Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome. 80000294 ]
[1.37 ] Characterization of the gut microbiota of Kawasaki disease patients by metagenomic analysis 80000556 ]
[1.38 ] Altered fecal microbiota composition in patients with major depressive disorder. 80000265 ]
[1.39 ] Gut microbiome of treatment-naïve MS patients of different ethnicities early in disease course 80001262 ]
[1.40 ] Gut microbiota profiling of pediatric nonalcoholic fatty liver disease and obese patients unveiled by an integrated meta-omics-based approach 80000626 ]
[1.41 ] Gut microbiota and endothelial dysfunction markers in obese Mexican children and adolescents 80001006 ]
[1.42 ] Diversity analysis of gut microbiota in osteoporosis and osteopenia patients 80001198 ]
[1.43 ] Gut microbiota altered in mild cognitive impairment compared with normal cognition in sporadic Parkinson’s disease 80001370 ]
[1.44 ] Early-onset preeclampsia is associated with gut microbial alterations in antepartum and postpartum women 80001138 ]
[1.45 ] Gut microbiota dysbiosis in a cohort of patients with psoriasis 80001039 ]
[1.46 ] Altered gut microbiota in Rett syndrome 80000534 ]
[1.47 ] Analysis of gut mycobiota in first-episode, drug-naïve Chinese patients with schizophrenia: a pilot study 80001250 ]
[1.48 ] Altered mucosal microbiome diversity and disease severity in Sjögren Syndrome 80000347 ]
[1.49 ] Gut microbiota dysbiosis in male patients with chronic traumatic complete spinal cord injury 80000938 ]
[1.50 ] Comparison of the ocular microbiome between chronic Stevens-Johnson syndrome patients and healthy subjects 80001339 ]
[1.51 ] Alterations in the gut microbiota and metabolite profiles of thyroid carcinoma patients 80000975 ]
[1.52 ] Analysis of endoscopic brush samples identified mucosa-associated dysbiosis in inflammatory bowel disease 80000679 ]
[1.53 ] Characteristics of fecal and mucosa-associated microbiota in Chinese patients with inflammatory bowel disease 80000665 ]
[1.54 ] Patients with acne vulgaris have a distinct gut microbiota in comparison with healthy controls 80000937 ]
[1.55 ] Alterations in the gut microbiota of patients with acquired immune deficiency syndrome 80000714 ]
[1.56 ] Changes in intestinal microflora in digestive tract diseases during pregnancy 80001321 ]
[1.57 ] Gut microbiota compositional and functional fingerprint in patients with alcohol use disorder and alcohol-associated liver disease 80001386 ]
[1.58 ] Altered microbiomes distinguish Alzheimer’s disease from amnestic mild cognitive impairment and health in a Chinese cohort 80001073 ]
[1.59 ] Gut microbiota profile in children affected by atopic dermatitis and evaluation of intestinal persistence of a probiotic mixture 80000949 ]
[1.60 ] Gut microbiota features in young children with autism spectrum disorders 80000980 ]
[1.61 ] Gut microbial profile in biliary atresia: a case-control study 80001225 ]
[1.62 ] The intestinal microbiota associated with cardiac valve calcification differs from that of coronary artery disease 80000915 ]
[1.63 ] Comparison of small gut and whole gut microbiota of first-degree relatives with adult celiac disease patients and controls 80000986 ]
[1.64 ] Alterations of gut microbiota in cholestatic infants and their correlation with hepatic function 80000981 ]
[1.65 ] Characterization of intestinal microbiota in alcoholic patients with and without alcoholic hepatitis or chronic alcoholic pancreatitis 80000689 ]
[1.66 ] Modulation of the fecal bile acid profile by gut microbiota in cirrhosis 80000580 ]
[1.67 ] Human intestinal lumen and mucosa-associated microbiota in patients with colorectal cancer 80000305 ]
[1.68 ] Gut mucosal microbiome across stages of colorectal carcinogenesis 80000724 ]
[1.69 ] Gut microbiome-based diagnostic model to predict coronary artery disease 80001414 ]
[1.70 ] Alterations in gut microbiota of patients with COVID-19 during time of hospitalization 80001420 ]
[1.71 ] Altered gut microbiota is present in newly diagnosed pediatric patients with inflammatory bowel disease 80001299 ]
[1.72 ] Fungal dysbiosis in mucosa-associated microbiota of Crohn’s disease patients 80000760 ]
[1.73 ] Impact of cystic fibrosis disease on archaea and bacteria composition of gut microbiota_DUBLICATE 80000628 ]
[1.74 ] Hepatic glycogen storage diseases are associated to microbial dysbiosis 80001020 ]
[1.75 ] Alterations in the intestinal microbiota of patients with severe and active Graves’ orbitopathy: a cross-sectional study 80000930 ]
[1.76 ] Alterations of the gut microbiota in patients with COVID-19 or H1N1 Influenza 80001419 ]
[1.77 ] A compositional look at the human gastrointestinal microbiome and immune activation parameters in HIV infected subjects. 80000332 ]
[1.78 ] An altered intestinal mucosal microbiome in HIV-1 infection is associated with mucosal and systemic immune activation and endotoxemia. 80000343 ]
[1.79 ] Gut microbiota dysbiosis contributes to the development of hypertension 80000033 ]
[1.80 ] The gut microbiome in epilepsy 80001252 ]
[1.81 ] Fungal microbiota dysbiosis in IBD 80000756 ]
[1.82 ] Characteristic dysbiosis of gut microbiota of Chinese patients with diarrhea-predominant irritable bowel syndrome by an insight into the pan-microbiome 80001123 ]
[1.83 ] Microbiome analytics of the gut microbiota in patients with juvenile idiopathic arthritis: a longitudinal observational cohort study 80001040 ]
[1.84 ] Landscapes of bacterial and metabolic signatures and their interaction in major depressive disorders 80001465 ]
[1.85 ] Multiple sclerosis patients have a distinct gut microbiota compared to healthy controls_DUBLICATE 80000891 ]
[1.86 ] Gut microbiome of multiple sclerosis patients and paired household healthy controls reveal associations with disease risk and course 80002601 ]
[1.87 ] Alterations of the gut microbiota in multiple system atrophy patients 80001371 ]
[1.88 ] Dysbiosis of gut microbiota in patients with neuromyelitis optica spectrum disorders: a cross sectional study 80001254 ]
[1.89 ] Characterization of gut microbiomes in nonalcoholic steatohepatitis (NASH) patients: a connection between endogenous alcohol and NASH 80000566 ]
[1.90 ] Nonalcoholic fatty liver disease is associated with dysbiosis independent of body mass index and insulin resistance 80000685 ]
[1.91 ] Gut microbial profile analysis by MiSeq sequencing of pancreatic carcinoma patients in China 80000728 ]
[1.92 ] Gut microbiota dysbiosis worsens the severity of acute pancreatitis in patients and mice. 80001237 ]
[1.93 ] Colonic bacterial composition in Parkinson’s Disease 80000275 ]
[1.94 ] Inflammatory microbes and genes as potential biomarkers of Parkinson’s disease 80002678 ]
[1.95 ] Metagenomics of Parkinson’s disease implicates the gut microbiome in multiple disease mechanisms 80002696 ]
[1.96 ] Comprehensive analysis of serum and fecal bile acid profiles and interaction with gut microbiota in primary biliary cholangitis 80000962 ]
[1.97 ] The gut microbiota, bile acids and their correlation in primary sclerosing cholangitis associated with inflammatory bowel disease 80000678 ]
[1.98 ] Fungi participate in the dysbiosis of gut microbiota in patients with primary sclerosing cholangitis 80000990 ]
[1.99 ] Gut microbial dysbiosis is associated with development and progression of radiation enteritis during pelvic radiotherapy 80001170 ]
[1.100 ] Gut microbiota perturbations in reactive arthritis and postinfectious spondyloarthritis 80000722 ]
[1.101 ] Alterations of gut microbiome in the patients with severe fever with thrombocytopenia syndrome 80000848 ]
[1.102 ] Fecal microbiota signatures of adult patients with different types of short bowel syndrome 80000662 ]
[1.103 ] Alterations in the gut microbiota of patients with silica-induced pulmonary fibrosis 80000939 ]
[1.104 ] Gut dysbiosis is prevailing in Sjögren’s syndrome and is related to dry eye severity 80001403 ]
[1.105 ] Dysbiosis of gut microbiota and short-chain fatty acids in acute ischemic stroke and the subsequent risk for poor functional outcomes 80001423 ]
[1.106 ] A single species of Clostridium subcluster XIVa decreased in ulcerative colitits patients 80000620 ]
[1.107 ] Gut microbiota composition and fecal metabolic phenotype in patients with acute anterior uveitis 80001190 ]
[1.108 ] Altered gut microbiome composition by appendectomy contributes to colorectal cancer 80002674 ]
[1.109 ] Beneficial reconstitution of gut microbiota and control of alpha-synuclein and curli-amyloids-producing enterobacteria, by beta 1,3-1,6 glucans in a clinical pilot study of autism and potentials in neurodegenerative diseases 80002371 ]
