Microbiome & Chronic Diseases

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Blautia ⇒ Clostridiales {10000258}

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References Notes

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Shared Reference Notes

  • [1.22
    - In patients with type 1 diabetes, elevated Blautia abundance was observed and was correlated with increased IA-2 tyrosine phosphatase autoantibodies, important markers of autoimmunity.
  • [1.88
    - The proportions of Blautia and F. Prausnitzii and absolute numbers of Blautia and Bifidobacterium species in the gut microbiome are directly correlated with the clinical stage of BC.
    - For instance, patients with stage 1 BC had a lower number of gut Blautia sp. in comparison with the ones with stage grade 3
  • [1.89
    - Protein powder consumption > decrease in Lachnospiraceae, Roseburia, Blautia, Synergistales, Coprococcus, Lactobacillales, Bacilli, Bifidobacterium longum and Firmicutes.
    - Protein powder consumption > higher abundance of Bacteroidetes.
  • [1.8
    - Severe Covid > higher abundance of four microbial species (i.e., Burkholderia contaminans, Bacteroides nordii, Bifidobacterium longum, and Blautia sp. CAG 257), six microbial pathways (e.g., glycolysis and fermentation), and 10 virulence genes > further associated with host immune response.
    - The abundance of Bu. contaminans > associated with higher levels of inflammation biomarkers and lower levels of immune cells.
    - human-origin proteins identified from both blood and fecal samples suggested gut barrier dysfunction in COVID-19 patients.
    - The circulating levels of lipopolysaccharide-binding protein increased in patients with severe illness > associated with circulating inflammation biomarkers and immune cells.
    - proteins of disease-related bacteria (e.g., B. longum) were detectable in blood samples from patients.
  • [1.79
    - Erectile dysfunction > no Alloprevotella .
    - Erectile dysfunction > increased streptococci and Subdoligranulum
    - Erectile dysfunction > decreased Prevotella sp.9, Blautia, Lachnospiraceae NK4A136 groups and Roseburia.
  • [1.90
    - MC/CFS > microbiome alterations that were consistent with an increased inflammation of the gut, namely significantly increased Lactonifactor and Alistipes
    - in particular an increase of Alistipes and a decrease of butyrate-producer Faecalibacterium were considered as top biomarkers with potential diagnostic value
    - abundance of Bifidobacterium and Faecalibacterium to be reduced in the affected twin compared to the non-affected one.
    - Decreases in Faecalibacterium and increases in Coprobacillus were found.
    - Gut abundances of Coprobacillus, of Eggerthella and Blautia were best able to distinguish patients from controls.
    - Decreases in Faecalibacterium and increases in Coprobacillus were found.
    - distinct microbial pattern with decreased anti-inflammatory Firmicutes
  • [1.61
    - A drastic disappearance of obligate anaerobic gut commensals (Blautia, Prevotella, Faecalibacterium, Lachnospiraceae, Ruminococcaceae, etc.), leading to a depletion of associated metabolites such as short chain fatty acid (SCFAs)
  • [1.59
    - Abundance of Blautia and Odoribacter showed a negative correlation with high SBP
  • [1.75
    - Prevotellaceae (Prevotella), Ruminococcaceae (Faecalibacterium), Lachnospiraceae (Blautia, Roseburia) that produce SCFA and help in the synthesis of mucin to maintain the intestinal integrity are considerably lower in abundance in PD

Common References