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Microbiome & Chronic Diseases

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Bacteroides ⇒ Bacteroidaceae {10000109}

Record Keys


Organism:
Bacteroides
Parent:

Details


Initialisation date:
2020-09-06

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Meta Information


Rank:
 Genus
Domain:
 Bacteria
Zone:[  ]
Enzyme:[  ]
Function:
Anti fibrosis

Notes:


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References Notes


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Shared Reference Notes


  • [1.155
    - The identified microbiome pattern of healthy ageing is characterized by a depletion of core genera found across most humans, primarily Bacteroides. - Retaining a high Bacteroides dominance into older age, or having a low gut microbiome uniqueness measure, predicts decreased survival in a 4-year follow-up.
  • [1.156
    - Patients with #Major depressive disorder showed a statistically significant overrepresentation of Bacteroides enterotype 2 compared to controls.
  • [1.123
    - Bacteroides is a common member of the gut microbiome and plays important, symbiotic roles, such as modulation and regulation of the immune system, maintenance of intestinal integrity, and carbohydrate digestion. - Bacteroides organisms are major producers of short-chain fatty acids, which have been shown to support host immune homeostasis both locally and systemically
  • - γ-aminobutyric acid (#GABA) production by human-derived Bacteroides is widespread, and there is a correlation between brain signatures of depression and fecal Bacteroides levels in patients with #Major depressive disorder.
  • [1.157] [#Non-alcoholic fatty liver disease
    - Some Bacteroides species have been reported to be protective against MAFLD
  • [#Steatohepatitis] - Bacteroides was negatively associated with advanced steatosis - Some species of Bacteroides have been associated with progression to advanced liver fibrosis
  • [1.158
    - Bacteroides predominate with protein and #Animal fat consumption.
  • [1.159] [#Galactooligosaccharides & modified mogrosides Sweetener
    - Significant growth during the fermentation at 10 h of bacterial populations includes #Bifidobacterium, Bacteroides, #Enterococcus, and #Clostridium coccoides. - significant increase in production of SCFA in mMV-GOS at 10 h of fermentation, mainly seen in #Acetate and #Propionate production
  • [1.160] [#Alzheimer’s disease
    - Increasing the relative abundance of Bacteroides and #Faecalibacterium may improve cognitive levels
  • [1.101
    - Members of the genera #Oscillospira and #Coprococcus in the cecum, as well as #Faecalibacterium prausnitzii and members of the genus Bacteroides in the ileum > negatively correlated with #Fibrosis.
  • [1.84] [#Carbohydrate diet, #High protein / animal fat diets
    - high protein animal fat diets are associated with Bacteroides, whereas diets high in carbohydrates are associated with a high prevalence of #Prevotella
  • [#Chronic fatigue syndrome] - Several studies reported a reduction of a butyrate-producing Bacteroides species in ME/CFS
  • [1.145] [#Resistant starch
    - RS consumption was associated with an increased abundance of either Bacteroides or #Prevotella transcripts.
  • [1.154
    - #Butyrate inhibits gut microbiome Bacteroides - #Butyrate inhibition depends on which #Sugar a given Bacteroides strain uses - Core genome variation in Acyl-CoA enzymes mediates #Butyrate defense - Each Bacteroides unique fitness landscape unpredictable by interaction of ecosystem parts
  • [1.161
    - #Firmicutes and Bacteroides are the main #Butyrate producing phyla
  • [1.25] [#Diabetes Type 1] [#Lipopolysaccharide
    - lipopolysaccharides biosynthesis in Bacteroides MAGs (metagenome-assembled genomes) and #Sulfate reduction in #Anaerostipes MAGs as functional signatures of MAGs with positive IA-association (Islets autoantibody)
  • [#Diabetes Type 1] [#Lipopolysaccharide] - LPS produced by the Bacteroides species in gut microbiota has immunoinhibitory properties that may impede early immune education and contribute to the development of T1D.
  • [1.128
    -The antibacterial and antitumor defensin (HBD1) showed decreased levels in #Prostate cancer patients, while others (HBD2 and 3) were considerably increased. - Abundance of #Staphylococcus, #Corynebacterium and #Oxyphotobacteria genera was significantly higher, the abundance of #Faecalibacterium and Bacteroides genera were significantly lower in prostate tumor samples compared to non-tumor samples. - Bacteroides, Parabacteroides and #Faecalibacterium abundance gradually decreased with the combined increase in HBD2 and HBD3. - Higher #Corynebacterium and #Staphylococcus abundances were measured together with higher HBD2 and HBD3 urinary levels.
  • [1.56] [#Parkinson’s Disease
    - an abundance of Bacteroides (Gram-negative bacteria present in the gut microbiome) is associated with the severity of motor symptoms in PD
  • [1.40] [#Irritable bowel syndrome
    - symptom severity is related to characteristic alterations of gut microbiota, including reduced diversity, reduced exhaled methane, relative reduction of #Methanobacteriales and #Prevotella enterotype, and abundance of Bacteroides enterotype. - Bacteroides were found to be increased in patients with IBS-D and were associated with mucosal low-grade inflammation.
  • [1.162] [#Animal fat consumption
    - diet with high content of animal fat was consumed Bacteroides-dominated enterotype was present
  • [1.24] [#Colitis, #Diabetes Type 1
    - The protein expressed by the Bacteroides is almost identical to a protein expressed by insulin-producing cells in the pancreas. - The CD8 lymphocytes can mistakenly attack the pancreatic cells and cause type 1 diabetes.

Common References