Disease ⇒ Myasthenia gravis {40000371}

Record Keys

Parent:[  ]
Myasthenia gravis


Initialisation date:[  ]
Other Terms:

Meta Information

MedDra ID:
MedDra Level:
ICD:[  ]
Category:[  ]
Zone:[  ]
Mechanism:[  ]


[  ]

Shared Reference Notes

  • [1.1
    - #Alternaria and Cladosporium species have been found to reveal acetylcholinesterase inhibitory activities. - acetylcholinesterase inhibitors are common therapeutics in MG, but further studies need to clarify potential benefits of these fungal genera in MG.
  • [#Candida albicans] - in one MG patient, C. albicans was dominantly present.
  • [1.2
    - #Butyric acid-producing gut bacteria and serum #Butyric acid level are reduced in patients with AChR MG. - #Butyrate supplementation effectively enhanced Treg differentiation and their suppressive function of AChR MG. - #Butyrate activates autophagy of Treg cells by inhibiting the mammalian target of rapamycin. - Activation of autophagy increased oxidative phosphorylation and surface expression of cytotoxic T-lymphocyte-associated protein 4 on Treg cells, thereby promoting Treg differentiation and their suppressive function in AChR MG
  • [1.3
  • [1.4

References Notes

[  ]

Common References

MetaBiom only uses strictly necessary session cookies to give you the best possible experience on the website. By selecting "Accept essential cookies" you agree to the use of these cookies.