Prevotellaceae ⇒ Paraprevotella {10000833}

Record Keys


Parent:
Definition:
Paraprevotella

Details


Initialisation date:[  ]

Meta Information


Rank:
 Genus
Domain:
 Bacteria
Zone:[  ]
Enzyme:[  ]
Function:
Trypsin-degrading

Notes:


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Shared Reference Notes


  • [1.1] [#Behcet’s Disease] [#Butyrate, #Lactate, #Lipopolysaccharide
    - These results showed that the gut microbiota in BD patients was enriched with lactic acid-producing bacteria, #Sulfate-reducing bacteria, and some opportunistic pathogens but lacked #Butyric acid-producing bacteria and methanogenic bacteria. - In mice receiving BD feces, it was observed that the intestinal barrier was disrupted with low expression of tight-junction proteins, leading to LPS release into circulation. - enrichment of #Bilophila, Alistipes, and Paraprevotella was observed in the BD-recipient group.
  • [1.2] [#Covid-19
    - Paraprevotella colonization inhibits lethal infection with murine hepatitis virus-2, a mouse coronavirus that is dependent on trypsin and trypsin-like proteases for entry into host cells
  • [#IG A] - Paraprevotella strains isolated from the faecal microbiome of healthy human donors are potent trypsin-degrading commensals. Mechanistically, Paraprevotella recruit trypsin to the bacterial surface through type IX secretion system-dependent polysaccharide-anchoring proteins to promote trypsin autolysis. - Paraprevotella colonization protects IgA from trypsin degradation and enhances the effectiveness of oral vaccines against Citrobacter rodentium.
  • [1.3] [#Chronic fatigue syndrome] [#Ruminococcaceae
    - genus Paraprevotella and Ruminococcaceae_UCG_014 were positively associated with ME/CFS risk.
  • [1.4
    - #Vogt-Koyanagi-Harada syndrome (VKH) > In this uveitis syndrome, a study demonstrated heightened levels of gram-negative bacteria, eg, #Bacteroides and Paraprevotella, in patients’ stools with a decrease in #Butyrate-producing bacteria.

References Notes


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Common References


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