Ruminococcaceae ⇒ Clostridiales {10000223}
| Organism: | Ruminococcaceae |
|---|---|
| Parent: |
| Initialisation date: | 2019-08-18 |
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| Rank: | Family |
|---|---|
| Domain: | Bacteria |
| Zone: | [ ] |
| Enzyme: | [ ] |
| Function: | Mucin-degrading, Anti-cancer |
Notes:
- The second mucin-degrading enterotype is rich in Ruminococcus and Akkermansia, both able to degrade mucins. (1)
Shared Notes
- [1.64]
-The family Ruminococcaceae has been consistently reported as less abundant in NAFLD - [1.65]
- High-protein group > decreased abundance of Veillonellaceae, Akkermansia, uncultured Eggerthellaceae, and Ruminococcaceae UCG-010 - [1.66]
- Oral administration of castalagin > enriched for bacteria associated with efficient immunotherapeutic responses (Ruminococcaceae and Alistipes) and improved the CD8+/Foxp3+CD4+ ratio within the tumor microenvironment. - [1.67]
- Exercise > increase the relative abundance of Verrucomicrobia, Akkermansia and Ruminococcaceae_UCG-014 - - HFD > decrease relative abundance of Verrucomicrobia, Akkermansia , Ruminococcaceae_UCG-014 and Bifidobacteriaceae
- [1.45]
- A drastic disappearance of obligate anaerobic gut commensals (Blautia, Prevotella, Faecalibacterium, Lachnospiraceae, Ruminococcaceae, etc.), leading to a depletion of associated metabolites such as short chain fatty acid (SCFAs) - [1.41]
- bacteria with capacity of butyrate production, Lachnospiraceae and Ruminococcaceae, were depleted in individuals at a high risk of stroke. Fecal butyrate concentrations also were low in these people - - patients with HF have a decrease in butyrate-producing bacteria, especially, Lachnospiracea and Ruminococcacea families.
- reduction of the butyrate-producing Eubacterium Halli and Lachnospiracea is correlated with increased inflammation, severity of disease, heart damage and mortality - [1.63]
- Prevotellaceae (Prevotella), Ruminococcaceae (Faecalibacterium), Lachnospiraceae (Blautia, Roseburia) that produce SCFA and help in the synthesis of mucin to maintain the intestinal integrity are considerably lower in abundance in PD - [1.68]
- Ruminococcaceae (order Clostridiales) that are prominent producers of butyrate, decreased in relative abundance with a high-fat diet.
- This decrease is particularly significant because Ruminococcaceae, making up ≈20% of gut bacteria in chow-fed OSA rats, decreased to ≈10% in high-fat OSA rats . Members of the order Clostridiales, other than Ruminococcaceae, also significantly decreased with high-fat diet.