Ruminococcaceae ⇒ Clostridiales {10000223}
| Organism: | Ruminococcaceae |
|---|---|
| Parent: |
| Initialisation date: | 2019-08-18 |
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| Rank: | Family |
|---|---|
| Domain: | Bacteria |
| Zone: | [ ] |
| Enzyme: | [ ] |
| Function: | Mucin-degrading, Anti-cancer |
Notes:
- The second mucin-degrading enterotype is rich in Ruminococcus and Akkermansia, both able to degrade mucins. (1)
References Notes
- (1) [1.69]
- (2) [1.70]
Shared Reference Notes
- [1.71] [#Non-alcoholic fatty liver disease]
-The family Ruminococcaceae has been consistently reported as less abundant in NAFLD - [1.67] [#High-protein diet]
- High-protein group > decreased abundance of #Veillonellaceae, #Akkermansia, uncultured #Eggerthellaceae, and Ruminococcaceae UCG-010 - [1.72] [#Cancer]
- Oral administration of #Castalagin > enriched for bacteria associated with efficient immunotherapeutic responses (Ruminococcaceae and #Alistipes) and improved the CD8+/Foxp3+CD4+ ratio within the tumor microenvironment. - [1.65] [#High-fat diet]
- HFD > decrease relative abundance of #Verrucomicrobia, #Akkermansia , Ruminococcaceae_UCG-014 and #Bifidobacteriaceae - [#Bifidobacteriaceae] [#Moderate Treadmill Exercise] - Exercise > increase the relative abundance of #Verrucomicrobia, #Akkermansia and Ruminococcaceae_UCG-014
- [1.45] [#Infectious diarrhea]
- A drastic disappearance of obligate anaerobic gut commensals (#Blautia, #Prevotella, #Faecalibacterium, #Lachnospiraceae, Ruminococcaceae, etc.), leading to a depletion of associated metabolites such as #Short Chain Fatty Acid (SCFAs) - [1.41] [#Heart failure] [#Eubacterium hallii, #Lachnospiraceae]
- patients with HF have a decrease in #Butyrate-producing bacteria, especially, Lachnospiracea and Ruminococcacea families. - reduction of the #Butyrate-producing Eubacterium Halli and Lachnospiracea is correlated with increased inflammation, severity of disease, heart damage and mortality - [#Ischemic stroke] - bacteria with capacity of butyrate production, #Lachnospiraceae and Ruminococcaceae, were depleted in individuals at a high risk of stroke. Fecal butyrate concentrations also were low in these people
- [1.68] [#Parkinson’s Disease]
- #Prevotellaceae (Prevotella), Ruminococcaceae (#Faecalibacterium), #Lachnospiraceae (#Blautia, #Roseburia) that produce SCFA and help in the synthesis of mucin to maintain the intestinal integrity are considerably lower in abundance in PD - [1.73] [#Inflamatory bowel disease, #Systemic anti-microbiota IgG]
- a modified high-throughput, culture-independent approach to quantify systemic IgG against gut commensal bacteria in human serum samples without the need for paired stool samples. - Using this approach, we highlight several commensal bacterial species that elicit elevated IgG responses in patients with inflammatory bowel disease (IBD) including taxa within the clades #Collinsella, #Bifidobacterium, #Lachnospiraceae, and Ruminococcaceae. - [1.74]
- Ruminococcaceae (order Clostridiales) that are prominent producers of #Butyrate, decreased in relative abundance with a #High-fat diet. - This decrease is particularly significant because Ruminococcaceae, making up ≈20% of gut bacteria in chow-fed OSA rats, decreased to ≈10% in high-fat OSA rats . Members of the order Clostridiales, other than Ruminococcaceae, also significantly decreased with #High-fat diet.