Disease
Microbiota ☳
Metabolome
Factor
Lachnospiraceae ⇒ Roseburia {10000139}
Record Keys
Parent:
Definition: Roseburia
Details
Initialisation date: 2019-08-11
Meta Information
Rank:
Domain:
Zone: [ ]
Enzyme: [ ]
Function: Anti-inflammatory
Notes:
[ ] Shared Reference Notes
[1.1 ] - Roseburia , was found to be reduced in IBD.
- It had the highest correlations occurring in a number of bile acids (e.g., taurocholate, taurochenodeoxycholate, glycocholate), in addition to several triacylglycerols (TAGs) and fatty acids.
- Specifically, the short chain fatty acid (SCFA) butyrate was found to be positively associated with Roseburia abundance, consistent with known butyrate production in the Roseburia genus.
- Roseburia has a known anti-inflammatory role in the intestine and it’s positive association with butyrate is consistent with a deficiency in this genus being highly predictive of IBD.
[1.2 ] [#Carbohydrate diet ] - Other butyrate producing microbes, e.g. Roseburia spp., fare better when they are delivered #Polysaccharide growth substrates in the diet
[1.3 ] [#Saturated fatty acids (SFAs) ] - SFAs were positively associated with Roseburia , a biomarker for the lean group.
[1.4 ] [#Therapeutic drugs ] - Statins combined with aspirin > synergistic reduction in serum atherogenic lipoproteins.
- Diuretic agents combined with beta-blockers > enrichment of intestinal Roseburia
[1.5 ] - #Protein powder consumption > decrease in #Lachnospiraceae , Roseburia , #Blautia , Synergistales, #Coprococcus , #Lactobacillales , Bacilli, #Bifidobacterium longum and #Firmicutes .
- #Protein powder consumption > higher abundance of #Bacteroidetes .
[1.6 ] [#Psychogenic erectile dysfunction ] - Erectile dysfunction > no #Alloprevotella .
- Erectile dysfunction > increased #Streptococci and #Subdoligranulum
- Erectile dysfunction > decreased #Prevotella sp.9, #Blautia , #Lachnospiraceae NK4A136 groups and Roseburia .
[1.7 ] [#Parkinson’s Disease ] - #Prevotellaceae (Prevotella), #Ruminococcaceae (#Faecalibacterium ), #Lachnospiraceae (#Blautia , Roseburia ) that produce SCFA and help in the synthesis of mucin to maintain the intestinal integrity are considerably lower in abundance in PD
[1.8 ] [#Omega 3 ] [#Omega 3 Supplementation ] - Roseburia may also be enhanced by omega-3 fatty acids in nuts, as its relative abundance was increased in humans as a result of both a walnut-supplemented diet and a diet with the same fatty-acid composition without walnuts
[1.9 ] [#Parkinson’s Disease ] - lower fecal #Butyrate and reduced counts of genera Roseburia , #Romboutsia , and #Prevotella are related to depressive symptoms in PD patients.
- Decreased levels of bacterially produced #Butyrate are related to epigenetic changes in leucocytes and neurons from PD patients and to the severity of their depressive symptoms.
[#Asthma ] [#Children ] - low α-diversity and relative abundance of particular gut-commensal bacteria genera (#Bifidobacterium , #Faecalibacterium , #Ruminococcus , and Roseburia ) are associated with childhood respiratory diseases.
[1.11 ] [#Vegetarian diet ] - Dominant species in vegetarians are #Ruminococcus , Roseburia , and #Eubacterium .
[1.12 ] [#Infants , #Mother-infant ] - Maternal gut strains transmitted after the first 3 months of life included members of the genera #Eubacterium , Roseburia , and #Blautia .
[1.13 ] [#Parkinson’s Disease ] [#Short Chain Fatty Acid ] - PD > a dramatic ~2.5-fold reduction for several SCFA producing species, and as much as 5 to 7.5 fold reduction in Roseburia species.
[1.14 ] [#Inflamatory bowel disease ] [#Short Chain Fatty Acid ] The first signs of aggravation of IBD are :
- a loss of the main anti-inflammatory Short-Chain Fatty Acids (SCFAs) Roseburia , #Eubacterium , #Subdoligranumum , #Ruminococcus
- an increase in pro-inflammatory pathogens #Proteus , #Finegoldia
- an increase of other minor SCFA producers such as #Ezakiella , #Anaerococcus , #Megasphaera , #Anaeroglobus , #Fenollaria .
- Further aggravation of clinical signs is significantly linked to the subsequent loss of these minor SCFAs species and to an increase in other proinflammatory Proteobacteria such as Klebsiella, Pseudomonas, Salmonella, Acinetobacter, Hafnia and proinflammatory Firmicutes such as Staphylococcus, Enterococcus, Streptococcus.
[1.15 ] [#Multiple Sclerosis ] [#Lipocalin-2 ] - bacteria thought to be beneficial for inflammatory bowel disease (IBD) such as #Anaerobutyricum , #Blautia , and Roseburia , were reduced in fecal Lcn-2-high MS patients.
[1.16 ] [#Crohn’s disease ] [#Clostridium cluster IV ] - Roseburia , #Gemmiger , #Coprococcus , #Ruminococcus 2, #Butyricicoccus , #Dorea , #Fusicatenibacter , #Anaerostipes , Clostridium IV were enriched in the healthy controls.
- #Blautia , Clostridium IV, #Coprococcus , #Dorea , #Fusicatenibacter continued to significantly decrease in early and advanced CD patients, and Escherichia/Shigella and Proteus continued to significantly increase.
- negative correlation between #Dorea , #Butyricicoccus , Roseburia and gland reduce, Roseburia and FC, #Butyricicoccus and goblet cells decreased, Parabacterodies and sex, Clostridium IV and CRP, #Dorea and ESR .
- positive correlation between Escherichia/Shigella and CRP, #Ruminococcus 2 and clinical symptoms.
[1.17 ] - Butyrylated high-amylose maize resistant starch decreased red meat-derived pro-mutagenic adduct O6-methyl-2-deoxyguanosine and related CRC risk.
- Certain #Butyrate -producing bacteria such as #Clostridium , #Ruminococcus , #Faecalibacterium spp., #Eubacterium spp., and Roseburia , were found to decrease in relative frequency in CRC patients.
- #Butyrate inhibited the growth of CRC cells and induced their apoptosis in vitro at pharmacologically high concentrations.
[1.18 ] [#Diabetes Type 2 ] - A reduction in the #Lachnospira , Roseburia , #Faecalibacterium and #Coprococcus genera in the T2D group.
- These genera were #Butyrate producers.
- The decrease of these genera favored #Obesity and the development of diseases.
[1.19 ] [#Bipolar disorder , #Major depressive disorder , #Schizophrenia ] - MDD and SZ shared higher levels of #Escherichia /#Shigella and #Veillonella whereas increased #Megasphaera and lower Roseburia are common for BD and SZ.
[#High-protein diet ] - Excessive protein intake > causing the growth of protein fermenting bacteria as #Clostridium , #Desulfovibrio , #Peptostreptococcus , #Acidaminococcus , #Veillonella , #Propionibacterium , Bacillus, #Bacteroides , #Staphylococcus , and other species of the #Proteobacteria family, and the loss of carbohydrate fermenting bacteria such as #Bacteroides , #Lactobacillus , #Bifidobacterium , #Prevotella , #Ruminococcus , Roseburia , and #Faecalibacterium .
[1.21 ] [#Crohn’s disease ] - The microbiome risk score (MRS) model yielded a hazard ratio (HR) of 2.24 and temporal validity by capturing individuals that developed CD up to five years prior to disease onset. The five most important taxa contributing to the MRS included #Ruminococcus torques , #Blautia , #Colidextribacter , an uncultured genus-level group from Oscillospiraceace, and Roseburia .
[1.22 ] [#Alzheimer’s disease ] - Increased proportions of #Odoribacter and #Barnesiella and decreased proportions of #Eubacterium , Roseburia , #Lachnoclostridium and #Collinsella were seen in elders with other #Dementia types than AD.
[1.23 ] [#Whole grains ] - Several #Butyrate -producers (e.g., #Faecalibacterium , Roseburia , Butyriciococcus) were inversely associated with colonic transit time and/or faecal pH, while the mucin-degraders #Akkermansia and #Ruminococcaceae showed the opposite association.
[1.24 ] [#Acute lymphoblastic leukemia ] - Roseburia , #Dialister , #Prevotella , #Faecalibacterium and #Anaerostipes showed reduced relative abundance in #Children with ALL at the time of diagnosis
[#Polysaccharide ] - #Cessation of breastfeeding initiates the transition towards an #Adult -like gut microbiome composition, which is characterized by expansion of Roseburia spp. and #Anaerostipes spp., restriction of #Lactobacillus spp. and a functional shift towards an increased capacity to degrade complex polysaccharides
- delayed maturation of the gut microbiome (characterized by reduced relative abundance of the genera Roseburia , #Dialister , #Prevotella , #Faecalibacterium and #Blautia and increased abundance of #Enterococcus ), as well as reduced stool levels of #Butyrate by the age of 12 months, is associated with aberrant immune responses and an increased risk of #Asthma diagnosis by the age of 5 years
[1.25 ] [#Faecalibacterium prausnitzii ] [#Aging ] - older subjects with physical #Frailty and #Sarcopenia > Lower abundance of F. prausnitzii, as well as members of the #Clostridiales class including #Eubacterium and Roseburia genera.
[#Immune checkpoint inhibitor ] - In multiple advanced #Melanoma datasets > Roseburia spp. associated with good response to ICI
[#Gestational fruit and vegetable consumption , #High fibre diet ] - Both total fibre and specific fruit and vegetable fibre intake, are associated with the relative abundance of bacteria of the Clostridia class in the gut microbiome, especially Roseburia genus
[1.26 ] - pPobiotic supplementation during #Antibiotic Therapy has a protective effect on #Blautia and Roseburia spp. levels
- #Blautia level has a tendency to normalize spontaneously after #Antibiotic Therapy .
[1.27 ] [#Systemic lupus erythematosus ] - SLE patients displayed higher serum levels of #IL-2 and #IL-6 .
- The abundance of Roseburia and #Faecalibacterium was inversely correlated with #IL-6 , the abundance of Roseburia had a negative correlation with #IL-2 , and the abundance of #Bacteroides had a positive correlation with #IL-2 .
[#Systemic lupus erythematosus ] - SLE > increased abundance of genera #Candidatus saccharimonas , #Desulfovibrio , #Odoribacter and Roseburia in mice treated with HCMVpp65 peptide is significantly correlated with lupus-like effects including enhanced levels of creatinine, proteinuria, glomerular damage and anti-dsDNA antibodies.
[1.28 ] [#High fibre diet ] - Both total fibre and specific fruit and vegetable fibre intake, are associated with the relative abundance of bacteria of the #Clostridia class in the gut microbiome, especially Roseburia genus.
[1.29 ] [#Inflamatory bowel disease ] [#Faecalibacterium prausnitzii ] - Decreased abundance on #Firmicutes bacteria belonging to the #Ruminococcaceae spp., #Lachnospiraceae spp, F. prausnitzii and Roseburia spp. families is a signature of microbial dysbiosis in IBD.
[#Clostridiales XIV , #Clostridium cluster IV ] - #Walnut consumption at 42 g/day, increased #Butyrate -producing #Clostridium clusters XIV and IV including, #Faecalibacterium , Roseburia , while lowering the relative abundance of #Ruminococcus , #Dorea , Oscilllo, #Bifidobacteria .
[#Almond ] - almonds (dose of 42 g/day) > increase in the relative amount of #Lachnospira , Roseburia , and #Dialister
[1.31 ] - #Riboflavin supplementation increased the abundance of bacteria that cannot synthesize #Riboflavin , such as #Faecalibacterium prausnitzii and Roseburia spp.
- Higher intake was also associated with an increase in the abundance of #Prevotella spp.
[1.32 ] [#Ulcerative Colitis ] [#Short Chain Fatty Acid ] - UC > depletion of SCFA-producing #Bacteria such as #Prevotella , Roseburia , #Lachnospiraceae , and #Ruminococcaceae .
[1.33 ] [#Pulmonary tubercolosis , #Tuberculosis ] - The genera #Parabacteroides , #Bacteroides , #Lachnoclostridium , and #Fusobacterium were markedly enhanced in the PTB group, while Roseburia , #Blautia , unidentified #Ruminococcaceae , #Bifidobacterium , #Romboutsia , and #Fusicatenibacter were enhanced in the HC group.
[1.34 ] - Early-stage #Melanoma had a higher alpha diversity, and a higher abundance of the genus Roseburia
[1.35 ] [#Clostridium cluster IV , #Clostridium clusters XIVa ] [#Butyrate ] - The predominant butyrogenic bacterial species, including #Faecalibacterium prausnitzii , #Clostridium spp., #Eubacterium spp., and Roseburia spp., are from two clusters (#Clostridium clusters IV and XIVa) in the #Firmicutes phylum and the #Clostridiales order
[1.36 ] [#Parkinson’s Disease ] - abundance of #Megasphaera and #Akkermansia , and reduced Roseburia in PD patients
[1.37 ] [#Lachnospiraceae ] [#Fiber-free diet ] - The lack of dietary fiber > reduced abundances of the #Butyrate -producing genera Lachnospiraceaea NK4A136 and Roseburia . Additionally, #Lactobacillus , which was also reduced in Fibre deprived mice
[1.38 ] [#Omega 3 ] - omega-3 rich diet has been shown to result in a significant increase in #Subdoligranulum , along with other #Butyrate producers like #Anaerostipes , #Coprococcus , and Roseburia .
[#Juvenile idiopathic arthritis ] [#Roseburia hominis ] - In JIA > reduced #Anaerostipes , #Dialister , #Lachnospira , and Roseburia have been correlated with rheumatic clinical indices including antibodies, erythrocyte sedimentation rate (ESR) and clinical JIA disease activity score.
- #Dialister , #Lachnospira , and Roseburia (Roseburia hominis in 0% of ABISJIA) were three of five genera reduced in ABISJIA, as well as an ASV belonging to #Anaerostipes .
[1.39 ] [#Obesity ] - In obese people, high indigestible carbohydrate intake can significantly increase #Firmicutes bacteria such as Ruminococci, Roseburia , and #Eubacterium rectale , whereas a lack of dietary fermentable carbohydrate intake can significantly decrease #Butyric acid -producing bacteria and, consequently, fecal #Butyric acid content
Intervention in Disease [ ]
Author: MetaBiom
Identifier: 10000139
URL: https://www.metabiom.org/microbiota/38/roseburia
Keywords: Microbiome, Dysbiosis, Microbiota, Organism, Bacteria
Common References
[1.1 ] Predictive Metagenomic Analysis of Autoimmune Disease Identifies Robust Autoimmunity and Disease Specific Microbial Signatures [2021] [Review] [Frontiers in Microbiology] [Journal] [80001705 ]
[1.2 ] Is eating behavior manipulated by the gastrointestinal microbiota? Evolutionary pressures and potential mechanisms [2014] [Review] [Bioessays] [Journal] [80001843 ]
[1.3 ] Gut Microbiota Profile and Its Association with Clinical Variables and Dietary Intake in Overweight/Obese and Lean Subjects: A Cross-Sectional Study [2021] [Clinical study] [Nutrients] [Journal] [80001896 ]
[1.4 ] Combinatorial, additive and dose-dependent drug–microbiome associations [2021] [Cohort study] [Nature] [Journal] [80002137 ]
[1.5 ] Fueling Gut Microbes: A Review of the Interaction between Diet, Exercise, and the Gut Microbiota in Athletes [2021] [Review] [Advances in Nutrition] [Journal] [80002173 ]
[1.6 ] Correlation between gut microbiota diversity and psychogenic erectile dysfunction [2021] [Study] [Translational Andrology and Urology] [Journal] [80002269 ]
[1.7 ] Exploring the multifactorial aspects of Gut Microbiome in Parkinson’s Disease [2022] [Review] [Folia Microbiologica] [Journal] [80002403 ]
[1.8 ] Rethinking healthy eating in light of the gut microbiome [2022] [Review] [Cell Host & Microbe] [Journal] [80002441 ]
[1.9 ] Bacterial Butyrate in Parkinson’s Disease Is Linked to Epigenetic Changes and Depressive Symptoms [2022] [Movement Disorders] [Journal] [80002465 ]
[1.10 ] The association between early-life gut microbiota and childhood respiratory diseases: a systematic review [2022] [Review] [The Lancet Microbe] [Journal] [80002550 ]
[1.11 ] Correlation between human gut microbiome and diseases [2022] [Review] [Infectious Medicine] [Journal] [80002594 ]
[1.12 ] Mobile genetic elements from the maternal microbiome shape infant gut microbial assembly and metabolism [2022] [Study] [Cell] [Journal] [80002657 ]
[1.13 ] Metagenomics of Parkinson’s disease implicates the gut microbiome in multiple disease mechanisms [2022] [Cohort study] [Nature communications] [Journal] [80002696 ]
[1.14 ] Gut microbiota analysis for prediction of clinical relapse in Crohn’s disease [2022] [Study] [Scientific Reports] [Journal] [80002707 ]
[1.15 ] Fecal Lcn-2 level is a sensitive biological indicator for gut dysbiosis and intestinal inflammation in multiple sclerosis [2022] [Study] [Frontiers in Immunology] [Journal] [80002718 ]
[1.16 ] Gut microbiota in the early stage of Crohn’s disease has unique characteristics [2022] [Study] [Gut Pathogens] [Journal] [80002734 ]
[1.17 ] Microbial Metabolite Dysbiosis and Colorectal Cancer [2023] [Review] [Gut and Liver] [Journal] [80002741 ]
[1.18 ] Variation of butyrate production in the gut microbiome in type 2 diabetes patients [2023] [Clinical study] [International Microbiology] [Journal] [80002763 ]
[1.19 ] Microbiota–gut–brain axis mechanisms in the complex network of bipolar disorders: potential clinical implications and translational opportunities [2023] [Review] [Molecular Psychiatry] [Journal] [80002837 ]
[1.20 ] Gut-Muscle Axis Exists and May Affect Skeletal Muscle Adaptation to Training [2020] [Review] [Nutrients] [Journal] [80002842 ]
[1.21 ] Gut Microbiome Composition is associated with future onset of Crohn’s Disease in Healthy First-Degree Relatives [Cohort study] [80002997 ]
[1.22 ] Alzheimer’s Disease Microbiome Is Associated with Dysregulation of the Anti-Inflammatory P-Glycoprotein Pathway [2019] [Research] [mBio] [Journal] [80000052 ]
[1.23 ] Effects of a wholegrain-rich diet on markers of colonic fermentation and bowel function and their associations with the gut microbiome: a randomised controlled cross-over trial [2023] [Study] [Frontiers in nutrition] [Journal] [80003001 ]
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[1.33 ] Host Microbiome in tuberculosis: Disease, treatment, and immunity perspectives [80003344 ]
[1.34 ] Gut Microbiome in Patients With Early-Stage and Late-Stage Melanoma [80003345 ]
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[1.60 ] Comparison of the ocular microbiome between chronic Stevens-Johnson syndrome patients and healthy subjects [2020] [Scientific Reports] [Journal] [80001339 ]
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[1.63 ] Analysis of endoscopic brush samples identified mucosa-associated dysbiosis in inflammatory bowel disease [2018] [Journal of Gastroenterology] [Journal] [80000679 ]
[1.64 ] Alterations in the gut microbiota of patients with acquired immune deficiency syndrome [2018] [Journal of Cellular and Molecular Medicine] [Journal] [80000714 ]
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[1.72 ] Behçet’s syndrome patients exhibit specific microbiome signature [2015] [Autoimmunity Reviews] [Journal] [80000507 ]
[1.73 ] Gut microbiota changes in patients with bipolar depression [2019] [Advanced Science] [Journal] [80001106 ]
[1.74 ] Alterations of gut microbiota in cholestatic infants and their correlation with hepatic function [2018] [Frontiers in Microbiology] [Journal] [80000981 ]
[1.75 ] Characterization of intestinal microbiota in alcoholic patients with and without alcoholic hepatitis or chronic alcoholic pancreatitis [2018] [Scientific Reports] [Journal] [80000689 ]
[1.76 ] A reduction in the butyrate producing species Roseburia spp. and Faecalibacterium prausnitzii is associated with chronic kidney disease progression [2016] [Antonie van Leeuwenhoek (2016)] [Journal] [80000548 ]
[1.77 ] Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers [2012] [The ISME Journal] [Journal] [80000715 ]
[1.78 ] Dysbiosis signatures of gut microbiota in coronary artery disease [2018] [Physiological genomics] [Journal] [80000879 ]
[1.79 ] Alterations in gut microbiota of patients with COVID-19 during time of hospitalization [2020] [Gastroenterology] [Journal] [80001420 ]
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[1.83 ] The altered gut microbiota in adults with cystic fibrosis [2017] [BMC Microbiology] [Journal] [80000425 ]
[1.84 ] Gut microbiota differs in composition and functionality between children with type 1 diabetes and MODY2 and healthy control subjects: a case-control study [2018] [Diabetes Care] [Journal] [80000812 ]
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[1.86 ] Intestinal microbiota is altered in patients with gastric cancer from Shanxi Province, China [2019] [Digestive Diseases and Sciences] [Journal] [80001028 ]
[1.87 ] Hepatic glycogen storage diseases are associated to microbial dysbiosis [2019] [PLOS ONE] [Journal] [80001020 ]
[1.88 ] The gut microbiota of hand, foot and mouth disease patients demonstrates down-regulated butyrate-producing bacteria and up-regulated inflammation-inducing bacteria [2018] [Acta Paediatrica] [Journal] [80000902 ]
[1.89 ] Helicobacter pylori infection alters gastric and tongue coating microbial communities [2019] [Helicobacter] [Journal] [80001045 ]
[1.90 ] Colonic mucosal microbiome differs from stool microbiome in cirrhosis and hepatic encephalopathy and is linked to cognition and inflammation [2012] [American Journal of Physiology-Gastrointestinal and Liver Physiology] [Journal] [80000587 ]
[1.91 ] Gut microbiome alterations in hereditary angioedema [2022] [Study] [Annals of Allergy, Asthma & Immunology] [Journal] [80002296 ]
[1.92 ] HIV infection is associated with compositional and functional shifts in the rectal mucosal microbiota [2013] [Microbiome] [Journal] [80000337 ]
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[1.95 ] Gut microbiota dysbiosis contributes to the development of hypertension [2017] [Review] [Microbiome] [Journal] [80000033 ]
[1.96 ] Altered intestinal microbiota and blood T cell phenotype are shared by patients with Crohn’s disease and their unaffected siblings [2014] [Gut] [Journal] [80000486 ]
[1.97 ] Molecular characterization of the intestinal microbiota in patients with and without abdominal bloating [2016] [American journal of physiology. Gastrointestinal and liver physiology] [Journal] [80000352 ]
[1.98 ] Alterations in the gut bacterial microbiome in fungal keratitis patients [2018] [PLOS ONE] [Journal] [80000884 ]
[1.99 ] Dysbiosis in the gut microbiota of patients with multiple sclerosis, with a striking depletion of species belonging to Clostridia XIVa and IV clusters. [2015] [PLOS ONE] [Journal] [80000233 ]
[1.100 ] Dysbiosis of gut microbiota in patients with neuromyelitis optica spectrum disorders: a cross sectional study [2020] [Journal of Neuroimmunology] [Journal] [80001254 ]
[1.101 ] Characterization of gut microbiomes in nonalcoholic steatohepatitis (NASH) patients: a connection between endogenous alcohol and NASH [2013] [Hepatology] [Journal] [80000566 ]
[1.102 ] Altered fecal microbiota correlates with liver biochemistry in nonobese patients with non-alcoholic fatty liver disease. [2016] [Scientific Reports] [Journal] [80000569 ]
[1.103 ] Gut microbiota composition and bone mineral loss-epidemiologic evidence from individuals in Wuhan, China [2019] [Osteoporosis International] [Journal] [80001182 ]
[1.104 ] Colonic bacterial composition in Parkinson’s Disease [2015] [Movement Disorders] [Journal] [80000275 ]
[1.105 ] Inflammatory microbes and genes as potential biomarkers of Parkinson’s disease [2022] [Review] [npj Biofilms and Microbiomes] [Journal] [80002678 ]
[1.106 ] Compositional and functional features of the female premenopausal and postmenopausal gut microbiota [2019] [FEBS Letters] [Journal] [80001233 ]
[1.107 ] Posttraumatic stress disorder is associated with altered gut microbiota that modulates cognitive performance in veterans with cirrhosis [2019] [American journal of physiology. Gastrointestinal and liver physiology] [Journal] [80001243 ]
[1.108 ] A Distinct Microbiome Signature in Posttreatment Lyme Disease Patients [2021] [Research] [mBio] [Journal] [80001737 ]
[1.109 ] The gut microbiota, bile acids and their correlation in primary sclerosing cholangitis associated with inflammatory bowel disease [2018] [United European Gastroenterology Journal] [Journal] [80000678 ]
[1.110 ] The gut-adherent microbiota of PSC-IBD is distinct to that of IBD [2017] [Gut] [Journal] [80000518 ]
[1.111 ] Alternation of gut microbiota in patients with pulmonary tuberculosis [2017] [Frontiers in Physiology] [Journal] [80000851 ]
[1.112 ] Gut microbiota perturbations in reactive arthritis and postinfectious spondyloarthritis [2018] [Arthritis & Reumatology] [Journal] [80000722 ]
[1.113 ] A comparative study of the gut microbiota in immune-mediated inflammatory diseases - does a common dysbiosis exist? [2018] [Microbiome] [Journal] [80000942 ]
[1.114 ] Alterations in intestinal microbiota diversity, composition, and function in patients with sarcopenia [2021] [Study] [Scientific Reports] [Journal] [80002671 ]
[1.115 ] Fecal microbiota signatures of adult patients with different types of short bowel syndrome [2017] [Journal of Gastroenterology and Hepatology] [Journal] [80000662 ]
[1.116 ] Connection between the Gut Microbiome, Systemic Inflammation, Gut Permeability and FOXP3 Expression in Patients with Primary Sjögren’s Syndrome [2020] [Research] [International journal of molecular sciences] [Journal] [80001479 ]
[1.117 ] Intestinal microbiota in patients with spinal cord injury [2016] [PLOS ONE] [Journal] [80001018 ]
[1.118 ] Faecal microbiota study reveals specific dysbiosis in spondyloarthritis [2017] [Annals of the Rheumatic Diseases] [Journal] [80000813 ]
[1.119 ] Dialister as a microbial marker of disease activity in Spondyloarthritis [2017] [Arthritis & Rheumatology] [Journal] [80000453 ]
[1.120 ] Dysbiosis of gut microbiota and short-chain fatty acids in acute ischemic stroke and the subsequent risk for poor functional outcomes [2020] [Research] [Journal of Parenteral and Enteral Nutrition] [Journal] [80001423 ]
[1.121 ] Disordered intestinal microbes are associated with the activity of systemic lupus erythematosus [2019] [Clinical Sciences ] [Journal] [80000934 ]
[1.122 ] Alterations in the gut microbiota and metabolite profiles of thyroid carcinoma patients [2019] [International Journal of Cancer] [Journal] [80000975 ]
[1.123 ] Gut microbiota dysbiosis in children with relapsing idiopathic nephrotic syndrome [2018] [American Journal of Nephrology] [Journal] [80000692 ]
[1.124 ] Gut microbiota composition and fecal metabolic phenotype in patients with acute anterior uveitis [2018] [Investigative Opthalmology & Visual Science] [Journal] [80001190 ]
[1.125 ] Association study of gut flora in Wilson’s disease through high-throughput sequencing [2018] [Medicine] [Journal] [80000863 ]
[1.126 ] An Almond-Based Low Carbohydrate Diet Improves Depression and Glycometabolism in Patients with Type 2 Diabetes through Modulating Gut Microbiota and GLP-1: A Randomized Controlled Trial [2020] [Clinical study] [Nutrients] [Journal] [80001462 ]
[1.127 ] Variability of strain engraftment and predictability of microbiome composition after fecal microbiota transplantation across different diseases [2022] [Study] [Nature medicine] [Journal] [80002616 ]
[1.128 ] Long-term daily high-protein, drained yoghurt consumption alters abundance of selected functional groups of the human gut microbiota and fecal short-chain fatty acid profiles in a cohort of overweight and obese women [2022] [Cohort study] [Journal of Functional Foods] [Journal] [80002459 ]
[1.129 ] Mediterranean diet intervention in overweight and obese subjects lowers plasma cholesterol and causes changes in the gut microbiome and metabolome independently of energy intake [2020] [Study] [Gut] [Journal] [80001473 ]
[1.130 ] Diet, obesity, and the gut microbiome as determinants modulating metabolic outcomes in a non-human primate model [2021] [Research] [Microbiome] [Journal] [80001840 ]
[1.131 ] Pharmacomicrobiomics: exploiting the drug-microbiota interactions in anticancer therapies [2018] [Research] [Microbiome] [Journal] [80000217 ]
[1.132 ] Temporospatial shifts in the human gut microbiome and metabolome after gastric bypass surgery [2020] [Study] [npj Biofilms and Microbiomes] [Journal] [80002685 ]
[1.133 ] Metformin Reduces Aging-Related Leaky Gut and Improves Cognitive Function by Beneficially Modulating Gut Microbiome/Goblet Cell/Mucin Axis [2020] [Research] [The Journals of Gerontology] [Journal] [80000214 ]
[1.134 ] Gut microbiota diversity and C-Reactive Protein are predictors of disease severity in COVID-19 patients [2021] [Research] [bioRxiv] [Journal] [80001803 ]