Disease ⇒ Coronary artery disease {40000234}

Record Keys


Type:
Disease
Parent:[  ]
Definition:
Coronary artery disease

Details


Initialisation date:[  ]
Other Terms:
CAD

Meta Information


MedDra ID:
10011078
MedDra Level:
pt
ICD:[  ]
Category:[  ]
Zone:[  ]
Mechanism:[  ]

Notes:


[  ]

Shared Reference Notes


  • [1.1
    - Long-term increases in TMAO were associated with higher CHD risk, and repeated assessment of TMAO over 10 years improved the identification of people with a higher risk of CHD. - Diet may modify the associations of ΔTMAO with CHD risk
  • [1.2] [#Atherosclerosis
    - #Bilophila, a genus of gut microbes, can metabolize #TMA, resulting in lower #TMAO, suggesting that differences in #TMA-metabolizing gut bacteria in individuals lead to different ultimate effects, and replacement of relevant bacteria may reduce the risk from #TMAO.
  • - #TMAO levels are also associated with #Heart failure and coronary artery disease. - #TMAO enhances the responsiveness of platelets to multiple agonists, promoting platelet hyperactivity and thus thrombosis and subsequent cardiovascular disease.
  • [1.3
    - a precursor to #TMAO, #trimethyllysine (TML), alone and combined with TAMO, is involved in cardiovascular events for patients with the acute coronary syndrome.
  • [1.4
    - genus #Oxalobacter was positively associated with the risk of CAD.
  • [1.5] [#Atrial fibrillation
    - #Eisenbergiella borderline differentially abundant in incident AF and significantly related to prevalent AF. - #Eisenbergiella is more abundant in normotensive persons. - the abundance of this genus is different in coronary artery disease patients. Which is a strong predictor and established risk factor of AF.
  • [1.6] [#CVD] [#Phenylacetylglutamine
    - the association between PAG and incident CAD is independent of inflammation, as the association remained significant after adjustment for CRP in MDC-CC.
  • - #Glutamate was strongly positively correlated and beta-carotene inversely correlated with cardiovascular risk factors.
  • [#Phenylacetylglutamine] - three genera in the #Lachnospiraceae family that were inversely correlated with PAG, were themselves positively correlated with the FRS. - association between PAG and incident CAD is significant in both individuals with high and with low of FRS.
  • [1.7] [#CVD
    - the abundance of #Bacteroidetes in patients with coronary artery disease (CAD) is lower than that in CAD patients without coronary risk factors or healthy volunteers

References Notes


[  ]

Common References


MetaBiom only uses strictly necessary session cookies to give you the best possible experience on the website. By selecting "Accept essential cookies" you agree to the use of these cookies.