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Disease ⇒ Coronary artery disease {40000234}

Record Keys


Type:
Disease
Definition:
Coronary artery disease
Parent:[  ]

Details


Initialisation date:[  ]
Other Terms:
CAD

Meta Information


MedDra ID:
10011078
MedDra Level:
pt
ICD:[  ]
Category:[  ]
Zone:[  ]
Mechanism:[  ]

Notes:


[  ]

References Notes


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Shared Reference Notes


  • [1.9
    - Long-term increases in TMAO were associated with higher CHD risk, and repeated assessment of TMAO over 10 years improved the identification of people with a higher risk of CHD. - Diet may modify the associations of ΔTMAO with CHD risk
  • [1.10] [#Atherosclerosis
    - #Bilophila, a genus of gut microbes, can metabolize #TMA, resulting in lower #TMAO,58 suggesting that differences in #TMA-metabolizing gut bacteria in individuals lead to different ultimate effects, and replacement of relevant bacteria may reduce the risk from #TMAO.
  • - #TMAO levels are also associated with #Heart failure and coronary artery disease. - #TMAO enhances the responsiveness of platelets to multiple agonists, promoting platelet hyperactivity and thus thrombosis and subsequent cardiovascular disease.
  • [1.8
    - a precursor to #TMAO, #trimethyllysine (TML), alone and combined with TAMO, is involved in cardiovascular events for patients with the acute coronary syndrome.
  • [1.7
    - genus #Oxalobacter was positively associated with the risk of CAD.

Common References