Microbiome & Chronic Diseases

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Disease ⇒ Coronary artery disease {40000234}

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Coronary artery disease


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Shared Reference Notes

  • [1.1
    - Long-term increases in TMAO were associated with higher CHD risk, and repeated assessment of TMAO over 10 years improved the identification of people with a higher risk of CHD. - Diet may modify the associations of ΔTMAO with CHD risk
  • [1.2] [#Atherosclerosis
    - #Bilophila, a genus of gut microbes, can metabolize #TMA, resulting in lower #TMAO, suggesting that differences in #TMA-metabolizing gut bacteria in individuals lead to different ultimate effects, and replacement of relevant bacteria may reduce the risk from #TMAO.
  • - #TMAO levels are also associated with #Heart failure and coronary artery disease. - #TMAO enhances the responsiveness of platelets to multiple agonists, promoting platelet hyperactivity and thus thrombosis and subsequent cardiovascular disease.
  • [1.3
    - a precursor to #TMAO, #trimethyllysine (TML), alone and combined with TAMO, is involved in cardiovascular events for patients with the acute coronary syndrome.
  • [1.4
    - genus #Oxalobacter was positively associated with the risk of CAD.
  • [1.5] [#Atrial fibrillation
    - #Eisenbergiella borderline differentially abundant in incident AF and significantly related to prevalent AF. - #Eisenbergiella is more abundant in normotensive persons. - the abundance of this genus is different in coronary artery disease patients. Which is a strong predictor and established risk factor of AF.

References Notes

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Common References