Disease
Microbiota ☳
Metabolome
Factor
Negibacteria ⇒ Bacteroidetes {10000142}
Record Keys
Parent:
Definition: Bacteroidetes
Details
Initialisation date: 2020-09-06
Meta Information
Rank:
Domain:
Zone: [ ]
Enzyme: [ ]
Function: [ ]
Notes:
- The main producers of butyrate
Shared Reference Notes
[1.49 ] [#Covid-19 ] - Bacteroidetes trigger intestinal immune cells to release interferons. Interferons are key factors that ramp up the body’s response to viruses and help eliminate cells that are infected.
- Bacteroidetes have a specific molecule on their cell surface called a #Glycolipid that causes intestinal immune cells to release antiviral interferons.
[1.53 ] - #Obesity alters the balance of #Firmicutes in non-obese individuals to Bacteroidetes phyla in obese ones.
[1.42 ] [#Diabetes Type 2 ] [#Niacin ] [#Microencapsulated delayed-release Nicotinic Acid ] - Gut-targeted delayed-release NA but not NAM produced a significant increase in the abundance of Bacteroidetes .
- In the absence of systemic side effects, these favorable microbiome changes induced by microencapsulated delayed-release NA were associated with an improvement of biomarkers for systemic insulin sensitivity and metabolic inflammation.
[1.54 ] [#High-fat diet ] - Bacteroidetes has a substrate preference for certain fats.
[1.55 ] [#Obesity ] - Bacteroidetes > prevalence is lower in obese people > low-calorie diet > proportion increasealong with weight loss based on a low-calorie diet .
[1.56 ] - Low levels of Bacteroidetes phylum > associate with #Obesity and #High fasting glucose > increases following the “good” diet and decreases following the “bad” diet
[1.44 ] - #Protein powder consumption > decrease in #Lachnospiraceae , #Roseburia , #Blautia , Synergistales, #Coprococcus , #Lactobacillales , Bacilli, #Bifidobacterium longum and #Firmicutes .
- #Protein powder consumption > higher abundance of Bacteroidetes .
[1.57 ] [#Alzheimer’s disease ] - Decrease in Bacteroidetes and #Alloprevotella and increase in #Proteobacteria , #Verrucomicrobia , #Akkermansia , and #Desulfovibrio > improve short-term memory ability and cognitive level of AD mice
[1.52 ] [#Sphingolipid ] - High ceramide levels > associated with insulin resistance, hypercholesterolemia, liver steatosis, and the formation of lipid rafts.
- Some classes of #Ceramides in the blood increase the risk for late-onset #Alzheimer’s disease , as they are neurotoxic and induce apoptosis .
- Bacteroidetes phylum can synthesize sphingolipids > human epithelial cells > #Ceramides
[1.58 ] [#Serine-glycine ] - Intraperitoneal administration of L654 over 7 weeks to HFD-fed Ldlr−/− mice resulted in hypocholesterolemic effects and significantly attenuated the progression of #Atherosclerosis .
- L654 and other bacterial glycine lipids in feces, liver, and serum were markedly reduced alongside changes in Bacteroidetes relative abundance in HFD-fed mice.
[1.59 ] [#Major depressive disorder ] - #Actinobacteria were found to be increased, whereas Bacteroidetes were decreased in relation to other phyla, and some studies suggested decreased microbial diversity in MDD patients
[1.11 ] - #Multiple Sclerosis > In the paediatric population, an inverse correlation has been observed between the phylum Bacteroidetes and Th17 cells (which are associated with autoimmunity)
[1.60 ] - #Low FODMAP diet > an increase in Bacteroidetes , a decrease in #Firmicutes species
[1.45 ] [#Clostridium difficile associated disease ] [#Administration of Vancomycin ] - vancomycin is used for C. difficile (CDI) which is associated with decrease in number of gut microbes like Bacteroidetes , #Fuminococcus , and #Faecalibacterium and increases in #Proteobacteria species.
[1.61 ] [#Fecal Microbiota Transplantation ] - recipients with higher donor strain engraftment were more likely to experience clinical success after FMT.
- Bacteroidetes and #Actinobacteria species (including Bifidobacteria) displayed higher engraftment than #Firmicutes except for six under-characterized #Firmicutes species.
[1.62 ] [#Culinary herbs and spices ] - higher #Firmicutes to Bacteroidetes ratio has been associated with #Obesity .
- decrease in #Firmicutes and increase in Bacteroidetes following spice intervention in humans
Author: MetaBiom
Identifier: 10000142
URL: https://www.metabiom.org/microbiota/41/bacteroidetes
Keywords: Microbiome, Dysbiosis, Microbiota, Organism, Bacteria
Common References
[1.1 ] Scalp bacterial shift in Alopecia areata [2019] [PLOS ONE] [Journal] [80001000 ]
[1.2 ] The microbiota of breast tissue and its association with breast cancer [2016] [Applied and Environmental Microbiology] [Journal] [80000898 ]
[1.3 ] Mucosal adherent bacterial dysbiosis in patients with colorectal adenomas [2016] [Scientific Reports] [Journal] [80000407 ]
[1.4 ] Gut microbiome-based diagnostic model to predict coronary artery disease [2020] [Journal of Agricultural and Food Chemistry] [Journal] [80001414 ]
[1.5 ] Altered gut microbiota profile in patients with generalized anxiety disorder [2018] [Journal of Psychiatric Research] [Journal] [80001066 ]
[1.6 ] Characterization of bacterial and fungal microbiome in children with Hirschsprung Disease with and without a history of enterolcolitis: a multicenter study [2015] [Research] [PLOS] [Journal] [80000666 ]
[1.7 ] Oral and airway microbiota in HIV-infected pneumonia patients [2012] [Journal of Clinical Microbiology] [Journal] [80000445 ]
[1.8 ] The lower airways microbiome and antimicrobial peptides in idiopathic pulmonary fibrosis differ from chronic obstructive pulmonary disease [2022] [Study] [PLOS ONE] [Journal] [80002207 ]
[1.9 ] Faecal microbiome in new-onset juvenile idiopathic arthritis. [2016] [European Journal of Clinical Microbiology & Infectious Diseases] [Journal] [80000344 ]
[1.10 ] Gut microbial signatures can discriminate unipolar from bipolar depression [2020] [Advanced Science] [Journal] [80001346 ]
[1.11 ] Role of the gut microbiota in the development of various neurological diseases [2022] [Review] [NeurologĂa (English Edition)] [Journal] [80002479 ]
[1.12 ] Metagenomics of Parkinson’s disease implicates the gut microbiome in multiple disease mechanisms [2022] [Cohort study] [Nature communications] [Journal] [80002696 ]
[1.13 ] Impact of Visceral Obesity on Structural and Functional Alterations of Gut Microbiota in Polycystic Ovary Syndrome (PCOS): A Pilot Study Using Metagenomic Analysis [80002698 ]
[1.14 ] Gut microbiota dysbiosis in preeclampsia patients in the second and third trimesters [2020] [Chinese Medical Journal] [Journal] [80001375 ]
[1.15 ] Intestinal dysbiosis associated with systemic lupus erythematosus [2014] [mBio] [Journal] [80000718 ]
[1.16 ] Alterations in diversity of the oral microbiome in pediatric inflammatory bowel disease [2012] [Inflammatory Bowel Diseases] [Journal] [80000404 ]
[1.17 ] The circulating microbiome signature and inferred functional metagenomics in alcoholic hepatitis [2018] [Hepatology] [Journal] [80000726 ]
[1.18 ] Colonic microbiome is altered in alcoholism [2012] [American Journal of Physiology-Gastrointestinal and Liver Physiology] [Journal] [80000588 ]
[1.19 ] Altered microbiomes distinguish Alzheimer’s disease from amnestic mild cognitive impairment and health in a Chinese cohort [2019] [Brain, Behavior, and Immunity] [Journal] [80001073 ]
[1.20 ] New and Preliminary Evidence on Altered Oral and Gut Microbiota in Individuals with Autism Spectrum Disorder (ASD): Implications for ASD Diagnosis and Subtyping Based on Microbial Biomarkers. [2019] [Nutrients] [Journal] [80001197 ]
[1.21 ] Oral microbiota in autoimmune polyendocrine syndrome type 1 [2018] [Journal of Oral Microbiology] [Journal] [80000749 ]
[1.22 ] Sequencing of 16S rRNA reveals a distinct salivary microbiome signature in Behcet’s disease [2016] [Clinical Immunology] [Journal] [80000770 ]
[1.23 ] Extensive description and comparison of human supra-gingival microbiome in root caries and health. [2015] [PLOS ONE] [Journal] [80000363 ]
[1.24 ] First insights into the gut microbiota of Mexican patients with celiac disease and non-celiac gluten sensitivity [2018] [Nutrients] [Journal] [80000874 ]
[1.25 ] The Gut Microbiome in Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS) [2022] [Review] [Frontiers in Immunology] [Journal] [80002273 ]
[1.26 ] Metagenome and metatranscriptome profiling of moderate and severe COPD sputum in Taiwanese Han Males [2016] [PLOS ONE] [Journal] [80000876 ]
[1.27 ] Decreased diversity of nasal microbiota and their secreted extracellular vesicles in patients with chronic rhinosinusitis based on a metagenomic analysis [2014] [Allergy] [Journal] [80000559 ]
[1.28 ] Comparative metagenomic study of alterations to the intestinal microbiota and risk o nosocomial clostridium difficile-associated disease [2010] [The Journal of Infectious Diseases] [Journal] [80000531 ]
[1.29 ] Inflammation-related differences in mucosa-associated microbiota and intestinal barrier function in colonic Crohn’s disease [2018] [American journal of physiology. Gastrointestinal and liver physiology] [Journal] [80000896 ]
[1.30 ] Metagenomic evidence for taxonomic dysbiosis and functional imbalance in the gastrointestinal tracts of children with cystic fibrosis [2016] [Scientific Reports] [Journal] [80000395 ]
[1.31 ] The relationship of gastric microbiota and Helicobacter pylori infection in pediatrics population [2020] [Helicobacter] [Journal] [80001374 ]
[1.32 ] Deep sequencing reveals microbiota dysbiosis of tongue coat in patients with liver carcinoma [2016] [Scientific Reports] [Journal] [80001032 ]
[1.33 ] Alterations in the Fecal Microbiota of Patients with HIV-1 Infection: An Observational Study in A Chinese Population [2016] [Scientific Reports] [Journal] [80000387 ]
[1.34 ] Intetinal microbiota in patients with nonalcoholic fatty liver disease [2013] [Hepatology] [Journal] [80000581 ]
[1.35 ] A core gut microbiome in obese and lean twins [2009] [Nature] [Journal] [80000312 ]
[1.36 ] Gut microbial profile is altered in primary biliary cholangitis and partially restored after UDCA therapy [2017] [Gut] [Journal] [80000594 ]
[1.37 ] Decreased bacterial diversity characterizes an altered gut microbiota in psoriatic arthritis and resembles dysbiosis of inflammatory bowel disease. [2015] [Arthritis Rheumatol] [Journal] [80000525 ]
[1.38 ] Alternation of gut microbiota in patients with pulmonary tuberculosis [2017] [Frontiers in Physiology] [Journal] [80000851 ]
[1.39 ] Drastic changes in fecal and mucosa-associated microbiota in adult patients with short bowel syndrome [2010] [Biochimie] [Journal] [80000557 ]
[1.40 ] Non-absorbable apple procyanidins prevent obesity associated with gut microbial and metabolomic changes [2016] [Research] [Scientific Reports] [Journal] [80001613 ]
[1.41 ] Effect of the Intake of a Traditional Mexican Beverage Fermented with Lactic Acid Bacteria on Academic Stress in Medical Students [2021] [Clinical study] [Nutrients] [Journal] [80001885 ]
[1.42 ] Targeted Microbiome Intervention by Microencapsulated Delayed-Release Niacin Beneficially Affects Insulin Sensitivity in Humans [2017] [Research] [Diabetes Care] [Journal] [80001812 ]
[1.43 ] Metformin Reduces Aging-Related Leaky Gut and Improves Cognitive Function by Beneficially Modulating Gut Microbiome/Goblet Cell/Mucin Axis [2020] [Research] [The Journals of Gerontology] [Journal] [80000214 ]
[1.44 ] Fueling Gut Microbes: A Review of the Interaction between Diet, Exercise, and the Gut Microbiota in Athletes [2021] [Review] [Advances in Nutrition] [Journal] [80002173 ]
[1.45 ] Correlation between human gut microbiome and diseases [2022] [Review] [Infectious Medicine] [Journal] [80002594 ]
[1.46 ] Diet, obesity, and the gut microbiome as determinants modulating metabolic outcomes in a non-human primate model [2021] [Research] [Microbiome] [Journal] [80001840 ]
[1.47 ] Maternal exposures and the infant gut microbiome: a systematic review with meta-analysis [2020] [Review] [Gut microbes] [Journal] [80001848 ]
[1.48 ] Oral Microbiome: Getting to Know and Befriend Neighbors, a Biological Approach [2022] [Review] [biomedicines] [Journal] [80002370 ]
[1.49 ] Microbes in your gut may be new recruits in the fight against viruses [2021] [Report] [National Geographic] [Journal] [80001778 ]
[1.50 ] Targeting the Gut Microbiome to Mitigate Immunotherapy-Induced Colitis in Cancer [2021] [Abstract] [Trends in Cancer] [Journal] [80001734 ]
[1.51 ] in periodontitis-diseased tissues, P. gingivalis was present, but not much LPS was evident in tissues. [2022] [Report] [80002428 ]
[1.52 ] Genome-microbiome interplay provides insight into the determinants of the human blood metabolome [2022] [Study] [bioRxiv] [Journal] [80002312 ]
[1.53 ] Microbiome and Breast Cancer: New Role for an Ancient Population [2020] [Review] [Frontiers in Oncology] [Journal] [80001809 ]
[1.54 ] Is eating behavior manipulated by the gastrointestinal microbiota? Evolutionary pressures and potential mechanisms [2014] [Review] [Bioessays] [Journal] [80001843 ]
[1.55 ] Insights into the role of gut microbiota in obesity: pathogenesis, mechanisms, and therapeutic perspectives [2018] [Review] [Protein & Cell] [Journal] [80002107 ]
[1.56 ] Personalized Nutrition by Prediction of Glycemic Responses [2015] [Cohort study] [Cell] [Journal] [80002172 ]
[1.57 ] Composition of intestinal flora affects the risk relationship between Alzheimer’s disease/Parkinson’s disease and cancer [2022] [Review] [Biomedicine & Pharmacotherapy] [Journal] [80002199 ]
[1.58 ] Gut microbiome-derived glycine lipids are diet-dependent modulators of hepatic injury and atherosclerosis [2022] [Study] [Journal of Lipid Research] [Journal] [80002429 ]
[1.59 ] Alterations of the gut microbiota in borderline personality disorder [2022] [Research] [Journal of Psychosomatic Research] [Journal] [80002445 ]
[1.60 ] Gut microbiota signatures and modulation in irritable bowel syndrome [2022] [Review] [Microbiome Research Reports] [Journal] [80002578 ]
[1.61 ] Variability of strain engraftment and predictability of microbiome composition after fecal microbiota transplantation across different diseases [2022] [Study] [Nature medicine] [Journal] [80002616 ]
[1.62 ] Gut microbial modulation by culinary herbs and spices [2023] [Review] [Food Chemistry] [Journal] [80002681 ]