Disease
Microbiota ☳
Metabolome
Factor
Rikenellaceae ⇒ Alistipes {10000159}
Record Keys
Parent:
Definition: Alistipes
Details
Initialisation date: 2019-08-04
Meta Information
Rank:
Domain:
Zone: [ ]
Enzyme: [ ]
Function: Non-Alocoholic Fermentation, Pro-inflamatory
Notes:
- Alistipes , which helps ferment our food without producing alcohol, generally improves the metabolic status of our gut and makes us more proficient at using the glucose we consume for energy.
- Alistipes is found in plants. High levels can be found in the gut of hibernating bears. (1)
Shared Reference Notes
[1.1 ] - Increased relative abundances of fecal #Oscillibacter and Alistipes > causally linked to decreased #Triglyceride concentration.
[1.2 ] [#Cancer ] - Oral administration of #Castalagin > enriched for bacteria associated with efficient immunotherapeutic responses (#Ruminococcaceae and Alistipes ) and improved the CD8+/Foxp3+CD4+ ratio within the tumor microenvironment.
[1.3 ] [#Chronic fatigue syndrome ] - MC/CFS > microbiome alterations that were consistent with an increased inflammation of the gut, namely significantly increased #Lactonifactor and Alistipes
- in particular an increase of Alistipes and a decrease of butyrate-producer #Faecalibacterium were considered as top biomarkers with potential diagnostic value
- abundance of #Bifidobacterium and #Faecalibacterium to be reduced in the affected twin compared to the non-affected one.
- Decreases in #Faecalibacterium and increases in #Coprobacillus were found.
- Gut abundances of #Coprobacillus , of #Eggerthella and #Blautia were best able to distinguish patients from controls.
- Decreases in #Faecalibacterium and increases in #Coprobacillus were found.
- distinct microbial pattern with decreased anti-inflammatory #Firmicutes
[1.4 ] [#Sleep Deprivation ] - fecal #Butyrate concentrations positively correlated with the relative abundance of #Butyricimonas .
- the abundance of SCFAs-producing microbes, such as #Butyricicoccus , #Butyricimonas , and Alistipes markedly decreased after SD.
- #Butyrate > significantly reduced after 48 h of SD > After 1 week of sleep recovery, #Butyrate concentrations returned.
[1.5 ] - A higher relative abundance of Alistipes species has been reported in children with #Autism , pervasive developmental disorder not otherwise specified (PDD-NOS) , and depression.
- Alistipes may disrupt the gut–brain axis by decreasing #Serotonin (indole-positive organism) and impair cognition by producing #Propionic acid in rats.
[1.6 ] [#Human gammaherpesvirus 4 ] - #Tomato > Fruitflow when administered over 4 wk at 2×150 mg Fruitflow per d > Significant changes in relative abundance of microbial taxa with Fruitflow, such as decreases in #Bacteroides , Ruminococccus, and #Hungatella related OTUs, as well as increases in Alistipes which are all known for the involvement in #TMA /#TMAO metabolism.
[1.7 ] [#Diabetes Type 2 ] - A significant reduction of genera Alistipes , #Anaerostipes , #Ruminococcus was detected in the T2D group.
[1.8 ] [#Plastics ] - Alistipes was increased under the intervention of food grade plastic bags.
[1.9 ] [#Bipolar disorder , #Major depressive disorder , #Schizophrenia ] - MDD was often characterized by higher Alistipes and #Parabacteroides and lower #Prevotella ; BD by higher #Bifidobacterium and #Oscillibacter ; and SZ by higher #Prevotella and lower #Bacteroides , #Haemophilus , and #Streptococcus
- Higher caffeine and #Coffee intake was related to higher alpha diversity higher relative abundance of #Faecalibacterium and Alistipes , and lower relative abundance of #Erysipelatoclostridium .
- After adjustment of vitamin B2 in multivariate analysis, the significant inverse association between #Erysipelatoclostridium count and caffeine intake remained statistically significant.
[1.11 ] [#Aging ] - the loss of #Lactobacillus and #Faecalibacterium , as well as the abundance of #Oscillibacter and Alistipes genera along with the #Eubacteriaceae family is linked to #Frailty in elderly people.
[1.12 ] - in neurodegenerative disease > The microbes with elevated populations, like #Bilophila , Butryicicoccus, Alistipes , #Enterococcus , #Lactobacillus , #Streptococcus , #Shigella , and #Desulfovibrio , have the metabolic capability to produce #Putrescine majorly by the #Putrescine III biosynthesis pathway.
[1.13 ] - strains that are similar to Alistipes sp. CAG:514 are known to produce #GABA .
[#Alzheimer’s disease , #Cognitive impairment , #Mild Cognitive Impairment ] [#Mediterranean Ketogen Diet ] - Participants with MCI on the MMKD had lower levels of #GABA -producing microbes Alistipes sp. CAG:514 and #GABA , and higher levels of #GABA -regulating microbes #Akkermansia muciniphila .
[#American Heart Association Diet ] - the low-fat AHAD modulates key #Neurotransmitters , such as promoting #GABA production, in individuals with #Cognitive impairment . This dysregulation may be related to increases in #GABA -producing microbes, such as Alistipes sp. CAG:514.
[1.14 ] [#Vogt-Koyanagi-Harada ] - An enriched Alistipes along with a lower level of #Dorea were observed in VKH patients.
[1.15 ] [#Alzheimer’s disease ] - Increased proportions of #Bacteroides , Alistipes , #Odoribacter , and #Barnesiella and decreased proportions of #Lachnoclostridium were present in AD elders.
[1.16 ] [#Alzheimer’s disease ] - Alistipes , #Barnesiella , and #Odoribacter were previously found in symptomatic individuals with AD.
[1.17 ] - Other genera in the #Bacteroidetes phyla are Alistipes , #Anaerorhabdus , #Dichelobacter , #Fibrobacter , #Megamonas , #Mitsuokella , #Rikenella , #Sebaldella , #Tannerella , and #Tissierella .
[1.18 ] [#Non-alcoholic fatty liver disease ] - An increase in #Dorea , combined with decreases in Alistipes appears to be characteristic of MAFLD patients.
[#Non-alcoholic fatty liver disease ] - #Ruminococcus obeum and Alistipes were most enriched in healthy individuals when compared with MAFLD patients.
[#Non-alcoholic fatty liver disease ] - In MAFLD > Alistipes has negatively related to serum #Glucose (GLU), gamma-glutamyl transferase (GGT), and alanine aminotransferase (ALT).
[1.19 ] [#Animal-based diet ] - increased #Animal protein intake is associated with increased relative abundance of Alistipes and #Bacteroides genera
- abundance of #Enterobacteriaceae and Alistipes was increased, and #Faecalibacterium abundance was decreased in patients with #Major depressive disorder
[1.21 ] - increased #Animal protein intake is associated with increased relative abundance of Alistipes and #Bacteroides genera
[1.22 ] [#Short Chain Fatty Acid ] - increased abundance of gut ##Ruminococcus and #Alistipes in castration-resistant #Prostate cancer (CRPC) patients along with ##Bacteroidales , ##Rikenellaceae , ##Faecalibacterium ,the so called SCFAs-producing microbiotas.
[#Prostate cancer ] [#Short Chain Fatty Acid ] - FMT with CRPC patients’ fecal suspension > increase SCFAs-producing gut microbiotas such as #Ruminococcus , Alistipes , Phascolarctobaterium in TRAMP, and correspondingly raised their gut SCFAs (#Acetate and ##Butyrate ) levels.
[1.23 ] - In patients with #Psoriatic Arthritis , there was a decrease in the abundance of certain bacteria such as #Akkermansia , #Ruminococcus , #Pseudobotyrivibrio , #Paraacteroides , Alistipes , and #Coprococcus
[1.24 ] [#Prostate cancer ] - #Anaerofilum is protective because it reduces inflammation caused by Alistipes , which produce pro-inflammatory mediators and raise the risk of PCA
[#Prostate cancer ] [#Short Chain Fatty Acid ] - #Subdoligranulum , #Lachnobacterium , #Christensenellaceae , #Lachnospira , #Rikenellaceae , #Eggerthella , and Alistipes are members of the SCFA-producing order #Clostridiales and were shown to be more prevalent in individuals with high-grade PCA.
[1.25 ] - #Ginger essential oil supplementation in PL mice enhanced the relative abundance of #Lactobacillus , Alistipes , and #Olsenella , which are considered beneficial bacteria.
[#Non alcoholic steatohepatitis ] [#Short Chain Fatty Acid ] - Alistipes , which are potential SCFA-producing bacteria that reduce hepatic fibrotic conditions through cytokine modulation, have been found at lower levels in the guts of NASH and NASH-#Cirrhosis patients
[1.26 ] [#Parkinson’s Disease ] [#Fiber-free diet , #Low fibre Diet ] - The lack of dietary fiber makes specialized taxa, which are equipped with glycan-degrading enzymes, such as #Akkermansia spp. or the Bacteriodetes genera Alistipes spp. and #Bacteroides spp.,65 switch to host #Glycans as energy resource, promoting mucus erosion and pathogens susceptibility.
Intervention in Disease [ ]
Author: MetaBiom
Identifier: 10000159
URL: https://www.metabiom.org/microbiota/58/alistipes
Keywords: Microbiome, Dysbiosis, Microbiota, Organism, Bacteria
Common References
[1.1 ] Mendelian randomization analyses support causal relationships between blood metabolites and the gut microbiome [2022] [Research] [nature genetics] [Journal] [80002183 ]
[1.2 ] A natural polyphenol exerts antitumor activity and circumvents anti-PD-1 resistance through effects on the gut microbiota [2022] [Study] [Cancer Discovery] [Journal] [80002247 ]
[1.3 ] The Gut Microbiome in Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS) [2022] [Review] [Frontiers in Immunology] [Journal] [80002273 ]
[1.4 ] Alterations of the Gut Microbiota in Response to Total Sleep Deprivation and Recovery Sleep in Rats [2022] [Study] [Nature and Science of Sleep] [Journal] [80002274 ]
[1.5 ] Shotgun Metagenomics Study Suggests Alteration in Sulfur Metabolism and Oxidative Stress in Children with Autism and Improvement after Microbiota Transfer Therapy [2022] [Study] [International journal of molecular sciences] [Journal] [80002687 ]
[1.6 ] A water-soluble tomato extract rich in secondary plant metabolites lowers trimethylamine-n-oxide and modulates gut microbiota: a randomized, double-blind, placebo-controlled cross-over study in overweight and obese adults [2022] [Study] [The Journal of Nutrition] [Journal] [80002731 ]
[1.7 ] Variation of butyrate production in the gut microbiome in type 2 diabetes patients [2023] [Clinical study] [International Microbiology] [Journal] [80002763 ]
[1.8 ] Effects of common plastic products heat exposure on cognition: Mediated by gut microbiota [2023] [Study] [Ecotoxicology and Environmental Safety] [Journal] [80002824 ]
[1.9 ] Microbiota–gut–brain axis mechanisms in the complex network of bipolar disorders: potential clinical implications and translational opportunities [2023] [Review] [Molecular Psychiatry] [Journal] [80002837 ]
[1.10 ] The Association between Caffeine Intake and the Colonic Mucosa-Associated Gut Microbiota in Humans—A Preliminary Investigation [2023] [Study] [Nutrients] [Journal] [80002846 ]
[1.11 ] How Microbiomes Affect Skin Aging: The Updated Evidence and Current Perspectives [2022] [Review] [Life] [Journal] [80002854 ]
[1.12 ] Comparative in-silico analysis of microbial dysbiosis discern potential metabolic link in neurodegenerative diseases [2023] [Review] [Frontiers in Neuroscience] [Journal] [80002870 ]
[1.13 ] Effects of a ketogenic and low‐fat diet on the human metabolome, microbiome, and foodome in adults at risk for Alzheimer’s disease [2023] [Study] [Alzheimer's & Dementia] [Journal] [80002874 ]
[1.14 ] Gut microbial signatures and their functions in Behcet’s uveitis and Vogt-Koyanagi-Harada disease [2023] [Journal of Autoimmunity] [Journal] [80002936 ]
[1.15 ] Alzheimer’s Disease Microbiome Is Associated with Dysregulation of the Anti-Inflammatory P-Glycoprotein Pathway [2019] [Research] [mBio] [Journal] [80000052 ]
[1.16 ] Gut microbiome composition may be an indicator of preclinical Alzheimer’s disease [2023] [Review] [Science translational medicine] [Journal] [80003029 ]
[1.17 ] Gut Microbiome–Brain Alliance: A Landscape View into Mental and Gastrointestinal Health and Disorders [2023] [Review] [ACS Chemical Neuroscience] [Journal] [80003039 ]
[1.18 ] Characteristics of gut microbiota in patients with metabolic associated fatty liver disease [80003040 ]
[1.19 ] Assessing the Performance of a Novel Stool-Based Microbiome Test That Predicts Response to First Line Immune Checkpoint Inhibitors in Multiple Cancer Types [2023] [Cohort study] [Cancers] [Journal] [80003055 ]
[1.20 ] Gut microbiota and its relation to inflammation in patients with bipolar depression: a cross-sectional study [2023] [Annals of General Psychiatry] [Journal] [80003100 ]
[1.21 ] Gut microbiome and nutrition-related predictors of response to immunotherapy in cancer: making sense of the puzzle [2023] [Study] [BJC Reports] [Journal] [80003179 ]
[1.22 ] Gut microbiota-derived short-chain fatty acids promote prostate cancer progression via inducing cancer cell autophagy and M2 macrophage polarization [2023] [Neoplasia] [Journal] [80003265 ]
[1.23 ] Association between gut microbiota and psoriasis: a bidirectional two-sample Mendelian randomization study [2023] [80003297 ]
[1.24 ] Probing the Relationship Between the Human Gut Microbiome and Prospects of Prostate Cancer: A Systematic Review [2023] [Cureus] [Journal] [80003298 ]
[1.25 ] Ginger essential oil prevents NASH progression by blocking the NLRP3 inflammasome and remodeling the gut microbiota-LPS-TLR4 pathway [2023] [80003336 ]
[1.26 ] Fiber deprivation and microbiome-borne curli shift gut bacterial populations and accelerate disease in a mouse model of Parkinson’s disease [2023] [80003413 ]
[1.27 ] Gut microbiota alterations in Alzheimer’s Disease [2017] [Scientific Reports] [Journal] [80000621 ]
[1.28 ] Lower airway microbiota and mycobiota in children with sever asthma [2018] [Journal of Allergy and Clinical Immunology] [Journal] [80001065 ]
[1.29 ] Characterization of the microbiome of nipple aspirate fluid of breast cancer survivors [2016] [Scientific Reports] [Journal] [80000890 ]
[1.30 ] High-throughput 16S rRNA gene sequencing reveals alterations of intestinal microbiota in myalgic encephalomyelitis/chronic fatigue syndrome patients. [2013] [Anaerobe] [Journal] [80000272 ]
[1.31 ] Understanding the gut-kidney axis among biopsy-proven diabetic nephropathy, type 2 diabetes mellitus and healthy controls: an analysis of the gut microbiota composition [2019] [Acta Diabetologica] [Journal] [80001227 ]
[1.32 ] Relationship between alterations of urinary microbiota and cultured negative lower urinary tract symptoms in female type 2 diabetes patients [2019] [BMC Urology] [Journal] [80001099 ]
[1.33 ] Gut microbiome and serum metabolome analyses identify molecular biomarkers and altered glutamate metabolism in fibromyalgia [2019] [EBioMedicine] [Journal] [80001184 ]
[1.34 ] Intestinal microbiota is altered in patients with gastric cancer from Shanxi Province, China [2019] [Digestive Diseases and Sciences] [Journal] [80001028 ]
[1.35 ] Gut microbiota dysbiosis in patients with hepatitis B virus-induced chronic liver disease covering chronic hepatitis, liver cirrhosis and hepatocellular carcinoma [2020] [Journal of Viral Hepatitis] [Journal] [80001388 ]
[1.36 ] Gut microbiome analysis as a tool towards targeted non-invasive biomarkers for early hepatocellular carcinoma [2018] [Gut] [Journal] [80000859 ]
[1.37 ] Structural alterations of faecal and mucosa-associated bacterial communities in irritable bowel syndrome [2012] [Environmental Microbiology Reports] [Journal] [80000629 ]
[1.38 ] Evidence for a distinct gut microbiome in kidney stone formers compared to non-stone formers [2016] [Urolithiasis] [Journal] [80000544 ]
[1.39 ] Correlation between the human fecal microbiota and depression. [2014] [Neurogastroenterology & Motility] [Journal] [80000264 ]
[1.40 ] Gut microbiome variation is associated to Multiple Sclerosis phenotypic subtypes [2020] [Annals of Clinical and Translational Neurology] [Journal] [80001342 ]
[1.41 ] Discrepant gut microbiota markers for the classification of obesity-related metabolic abnormalities [2019] [Scientific Reports] [Journal] [80001220 ]
[1.42 ] Identification and characterization of blood and neutrophil-associated microbiomes in patients with severe acute pancreatitis using next-generation sequencing [2018] [Frontiers in Cellular and Infection Microbiology] [Journal] [80000703 ]
[1.43 ] Gut microbiota altered in mild cognitive impairment compared with normal cognition in sporadic Parkinson’s disease [2020] [Frontiers in Neurology] [Journal] [80001370 ]
[1.44 ] Metagenomics of Parkinson’s disease implicates the gut microbiome in multiple disease mechanisms [2022] [Cohort study] [Nature communications] [Journal] [80002696 ]
[1.45 ] Alterations in the gut microbiota and metabolite profiles of thyroid carcinoma patients [2019] [International Journal of Cancer] [Journal] [80000975 ]
[1.46 ] Dysbiosis of gut microbiota with reduced tremethylamine-N-oxide level in patients with large-artery atherosclerotic stroke or transient ischemic attack._DUBLICATE [2015] [Journal of the American Heart Association] [Journal] [80000456 ]
[1.47 ] Persistent gut microbial dysbiosis in children with acute lymphoblastic leukemia (ALL) during chemotherapy [2020] [Microbial Ecology] [Journal] [80001424 ]
[1.48 ] Links of gut microbiota composition with alcohol dependence syndrome and alcoholic liver disease [2017] [Microbiome] [Journal] [80001336 ]
[1.49 ] Mild cognitive impairment has similar alterations as Alzheimer’s disease in gut microbiota [2019] [Alzheimer's & Dementia] [Journal] [80001081 ]
[1.50 ] New evidences on the altered gut microbiota in autism spectrum disorders [2017] [Microbiome] [Journal] [80000956 ]
[1.51 ] A metagenomic study of the gut microbiome in Behcet’s disease [2018] [Microbiome] [Journal] [80000793 ]
[1.52 ] Gut microbiota composition and Clostridium difficile infection in hospitalized elderly individuals: a metagenomic study [2016] [Scientific Reports] [Journal] [80001033 ]
[1.53 ] The gut microbiota in collagenous colitis shares characteristics with inflammatory bowel diseas-associated dysbiosis [2019] [Clinical and Translational Gastroenterology] [Journal] [80001117 ]
[1.54 ] Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers [2012] [The ISME Journal] [Journal] [80000715 ]
[1.55 ] Metabolomics and 16S rRNA sequencing of human colorectal cancers and adjacent mucosa [2018] [PLOS ONE] [Journal] [80001025 ]
[1.56 ] Analysis of endoscopic brush samples identified mucosa-associated dysbiosis in inflammatory bowel disease [2018] [Journal of Gastroenterology] [Journal] [80000679 ]
[1.57 ] Faecal proteomics: a tool to investigate dysbiosis and inflammation in patients with cystic fibrosis [2016] [Journal of Cystic Fibrosis] [Journal] [80000377 ]
[1.58 ] Alterations in Intestinal Microbiota Correlate With Susceptibility to Type 1 Diabetes. [2015] [Diabetes] [Journal] [80000838 ]
[1.59 ] Alterations in Fecal Microbiomes and Serum Metabolomes of Fatigued Patients With Quiescent Inflammatory Bowel Diseases [2021] [Clinical Gastroenterology and Hepatology] [Journal] [80001418 ]
[1.60 ] Gallstone Disease and Bacterial Metabolic Performance of Gut Microbiota in Middle-Aged and Older Patients [2022] [Clinical study] [International Journal of General Medicine] [Journal] [80002433 ]
[1.61 ] Hepatic glycogen storage diseases are associated to microbial dysbiosis [2019] [PLOS ONE] [Journal] [80001020 ]
[1.62 ] Molecular alteration analysis of human gut microbial composition in Graves’ disease patients [2018] [International Journal of Biological Sciences] [Journal] [80000858 ]
[1.63 ] Gut microbial dysbiosis is associated with altered hepatic functions and serum metabolites in chronic hepatitis B patients [2017] [Frontiers in Microbiology] [Journal] [80000704 ]
[1.64 ] HIV infection is associated with compositional and functional shifts in the rectal mucosal microbiota [2013] [Microbiome] [Journal] [80000337 ]
[1.65 ] Alterations in the gut microbiota associated with HIV-1 infection [2013] [Cell Host & Microbe] [Journal] [80000339 ]
[1.66 ] An altered intestinal mucosal microbiome in HIV-1 infection is associated with mucosal and systemic immune activation and endotoxemia. [2014] [Mucosal Immunology] [Journal] [80000343 ]
[1.67 ] The microbiome of translocated bacterial populations in patients with and without inflammatory bowel disease [2018] [Internal Medicine Journal] [Journal] [80000893 ]
[1.68 ] Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome. [2011] [Gastroenterology] [Journal] [80000294 ]
[1.69 ] Characterization of gut microbiomes in nonalcoholic steatohepatitis (NASH) patients: a connection between endogenous alcohol and NASH [2013] [Hepatology] [Journal] [80000566 ]
[1.70 ] Dysbiosis gut microbiota associated with inflammation and impaired mucosal immune function in intestine of humans with non-alcoholic fatty liver disease [2015] [Scientific Reports] [Journal] [80000572 ]
[1.71 ] Alterations in the colonic microbiota in response to osmotic diarrhea [2013] [PLOS ONE] [Journal] [80000474 ]
[1.72 ] Gut microbial profile analysis by MiSeq sequencing of pancreatic carcinoma patients in China [2017] [Oncotarget] [Journal] [80000728 ]
[1.73 ] Compositional and functional features of the female premenopausal and postmenopausal gut microbiota [2019] [FEBS Letters] [Journal] [80001233 ]
[1.74 ] Gut microbiota dysbiosis in a cohort of patients with psoriasis [2019] [British Journal of Dermatology] [Journal] [80001039 ]
[1.75 ] Decreased bacterial diversity characterizes an altered gut microbiota in psoriatic arthritis and resembles dysbiosis of inflammatory bowel disease. [2015] [Arthritis Rheumatol] [Journal] [80000525 ]
[1.76 ] Altered gut microbiota in Rett syndrome [2016] [Microbiome] [Journal] [80000534 ]
[1.77 ] The fecal microbiome in pediatric patients with short bowel syndrome. [2015] [Journal of Parenteral and Enteral Nutrition] [Journal] [80000244 ]
[1.78 ] Intestinal microbiome analysis revealed dysbiosis in sickle cell disease [2018] [American Journal of Hematology] [Journal] [80000719 ]
[1.79 ] Connection between the Gut Microbiome, Systemic Inflammation, Gut Permeability and FOXP3 Expression in Patients with Primary Sjögren’s Syndrome [2020] [Research] [International journal of molecular sciences] [Journal] [80001479 ]
[1.80 ] Faecal microbial dysbiosis in children with Wiskott-Aldrich syndrome [2020] [Journal of Immunology] [Journal] [80001296 ]
[1.81 ] Long-term daily high-protein, drained yoghurt consumption alters abundance of selected functional groups of the human gut microbiota and fecal short-chain fatty acid profiles in a cohort of overweight and obese women [2022] [Cohort study] [Journal of Functional Foods] [Journal] [80002459 ]
[1.82 ] Postnatal exposure to ambient air pollutants is associated with the composition of the infant gut microbiota at 6-months of age [2022] [Cohort study] [Gut microbes] [Journal] [80002582 ]
[1.83 ] Whole Body Vibration-Induced Omental Macrophage Polarization and Fecal Microbiome Modification in a Murine Model [2019] [Research] [International journal of molecular sciences] [Journal] [80000071 ]