Alistipes ⇒ Alistipes indistinctus {10001097}

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Alistipes indistinctus


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Shared Reference Notes

  • [1.1
    - Alistipes indistinctus was the most potent in consuming a wide variety of carbohydrates.
  • [#Diabetes Type 2] - Postprandial blood #Glucose levels were particularly reduced in mice administered with A. indistinctus, #Alistipes finegoldii and #Bacteroides thetaiotaomicron that were fed a high-fat diet. - Insulin tolerance tests also revealed that these strains ameliorated IR, most prominently by A. indistinctus administration. - A. indistinctus administration ameliorated body mass gain, ectopic triglyceride accumulation in the liver and #Glucose intolerance - Serum levels of HDL-C, adiponectin and, to a lesser extent, triglycerides, were also improved in mice that were treated with A. indistinctus. - carbohydrate oxidation was significantly reduced in mice that were treated with A. indistinctus, implying that carbohydrate use is limited. - A. indistinctus administration substantially altered caecal metabolites, characterized by a reduction in several carbohydrates including #Fructose, a lipogenic monosaccharide. - #Fructose was similarly reduced in the serum - The AUC of insulin tolerance test was positively correlated with the caecal monosaccharides #Fructose, #Glucose and #Mannose
  • [#Diabetes Type 2] - A. indistinctus administration improves lipid accumulation and thereby Insulin Resistance, while simultaneously reducing intestinal monosaccharide levels.

References Notes

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