Microbiome & Chronic Diseases

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Enterobacteriaceae ⇒ Enterobacteriales {10000123}

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Shared Reference Notes

  • [1.66
    - Members of the Enterobacteriaceae family have a proinflammatory lipopolysaccharide (LPS) in the outer membrane and can exacerbate inflammation. A high relative abundance of Enterobacteriaceae is reported in inflammatory bowel diseases, in metabolic disorders like type 2 diabetes, and in immune diseases like cancers.
  • [1.67
    - Stress-exposed mice > develop ileal dysbiosis, dominated by the expansion of Enterobacteriaceae.
    - Stress-induced glucocorticoids promote > apoptosis of CD45+CD90+ cells that normally produce IL-22, a cytokine that is essential for the maintenance of ileal mucosal barrier integrity.
    - Blockade of glucocorticoid signaling or administration of recombinant IL-22 > restores mucosal immunity, prevents ileal dysbiosis.
  • [1.68
    - Lactobacillus reuteri and Bifidobacterium adolescentis Probitica > reduction in depressive symptoms at four and eight weeks of treatment, and anxiety symptoms at four weeks.
    > improvement in sleep quality.
    - Lactobacillus reuteri and Bifidobacterium adolescentis Probitica > decrease in serum interleukin-6 levels.
    - Lactobacillus reuteri and Bifidobacterium adolescentis Probitica > increased Bifidobacteriaceae and Lactobacillacea, whereas it decreased Enterobacteriaceae in the gut microbiota composition.
  • [1.14
    - Chronic fatigue syndrome > lower anti-inflammatory species carriage and higher levels of pro-inflammatory bacterial species such as Enterobacteriaceae were found in a 16S rRNA stool sample analysis.
    - Higher levels of Enterococcus spp, Streptococcus spp, lower levels of the beneficial Bifidobacteria and decreased anti-inflammatory Firmicutes have been detected.
  • [1.34
    - The gut microbiome undergoes a dramatic taxonomic change upon diarrhea’s onset, favoring the proliferation of fast-growing facultative anaerobes. Proteobacteria (mostly Enterobacteriaceae/E. coli) and Streptococcus (mainly Streptococcus salivarius and Streptococcus gallolyticus) are most significantly enriched during this early phase
  • [1.69
    - a few putative pathobionts of the family Enterobacteriaceae, Enterococcaceae, which are assumed to possibly reduce the production of SCFA, produce endotoxins and neurotoxins that promote intestinal inflammation, are enriched in PD

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