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Disease ⇒ Anxiety {40000113}

Record Keys


Type:
Disease
Definition:
Anxiety
Parent:[  ]

Details


Initialisation date:
2020-09-06
Other Terms:
Generalized Anxiety Disorder

Links


Meta Information


MedDra ID:[  ]
MedDra Level:[  ]
ICD:[  ]
Category:
Psychiatry
Zone:[  ]
Mechanism:[  ]

Notes:


- Bifidobacterium longum increase of BDNF levels and normalization of behavior. (1)
- Bifidobacterium infantis exaggerated HPA stress response (1)

References Notes


[  ]

Shared Reference Notes


  • [1.1
    - Stress and anxiety are related to gut dysbiosis.
    - Ingesting Lactobacillus plantarum P-8 (P-8) improved stress/anxiety symptoms.
    - Symptoms were relieved by modulating gut microbiota and neuroactive potential.
  • [1.5
    - Combination of probiotics and polyphenol-rich prebiotics, a synbiotic >attenuates the chronic-stress induced inflammatory responses in the ileum and the prefrontal cortex promoting > resilience to the consequent depressive- and anxiety-like behaviors in male mice.
    - This effect may be attributed to specific synbiotic-produced metabolites including 4-hydroxyphenylpropionic, 4-hydroxyphenylacetic acid and caffeic acid > promoted anti-inflammatory activity through the aryl hydrocarbon receptor (AHR).
  • [1.2
    - Lactobacillus reuteri and Bifidobacterium adolescentis Probitica > reduction in depressive symptoms at four and eight weeks of treatment, and anxiety symptoms at four weeks.
    > improvement in sleep quality.
    - Lactobacillus reuteri and Bifidobacterium adolescentis Probitica > decrease in serum interleukin-6 levels.
    - Lactobacillus reuteri and Bifidobacterium adolescentis Probitica > increased Bifidobacteriaceae and Lactobacillacea, whereas it decreased Enterobacteriaceae in the gut microbiota composition.
  • [1.3
    - mice exposed to 4EPS displayed anxiety-like behaviours, and pharmacological treatments that promote oligodendrocyte differentiation prevented the behavioural effects of 4EPS.