Microbiome & Chronic Diseases

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Lactobacillaceae ⇒ Lactobacillus {10000118}

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- Lactubacillus are reduced in chronic stress conditions, Can Lactobacillus probiotics relieve chronic stress?

References Notes

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Shared Reference Notes

  • [1.161
    - Two species from Lactobacillus genus ( Lactobacillus johnsonii, Lactobacillus gasseri) act upon mitochondria in the liver leading to the improvement of lipid metabolism. - Metabolomics analyses revealed that reduced glutathione may mediate these effects. - The mice receiving those Lactobacilli also had a lower fat mass index than those fed only a western diet
  • [1.162
    - The glutamate decarboxylase gen in some LAB strains is a potential GABA producer. - There are varying levels of inhibition against fungi, with Lactiplantibacillus plantarum and Lentilactobacillus parabuchneri exhibiting the highest suppression against the some strains of Fusarium, Aspergillus, and Penicillium. - The antifungal activity is mainly due to the activity of acids produced by LAB. - The antibacillus activity reveals a high inhibition potential of the majority of LAB isolated from sourdough against some strains of Bacillus.
  • [1.163
    - Lactobacillus can resist the antimicrobial activity of bile salts.
  • [1.164
    - Smectite clay promotes lactic acid bacteria (LABs) to form biofilms on its surface - Smectite with LABs inhibits tumor growth in mice - Smectite with LABs enhances anti-#Cancer chemo/immunotherapy in mice - Smectite with LABs activates dendritic cells via TLR2 signaling
  • [1.165] [#Probiotic (Bifidobacter and Lactobacilus)
    - The administration of a probiotic cocktail, composed of Lactobacillus rhamnosus and Lactobacillus helveticus, reduced the symptoms of #Depression and anxiety
  • - Following an extremely stressful period, fewer species of Lactobacillus are present in the stool.
  • - Lactobacillus can produce #Acetylcholine
  • - Lactobacillus can produce #GABA
  • [1.166] [#Polycystic ovary syndrome
    - Lactobacillus given to letrozole-treated (induces PCOS) rats reduced androgen levels, improved estrous cyclicity, normalized ovarian morphology, as well as increased Lactobacillus and #Clostridium species and decreased #Prevotella.
  • [1.149
    - A diet rich in salt (i.e. #High salt diet, or HSD) for instance, can result in depletion of the gut bacteria Lactobacillus spp., which results in T helper cell-mediated immune dysregulation and cognitive dysfunction. - A diet rich do not increase the serum concentration of proinflammatory molecules. - Adult male offspring from HSD-fed mice show hyperactivity, reduced sociability and increased repetitive behaviors
  • [1.143] [#Fermented food
    - The excellent biological activities of these functional foods, such as anti-inflammatory and immunomodulatory functions, are widely attributable to their high antioxidant content and lactic acid-producing bacteria
  • [1.159
    - #Acetylcholine is produced from Lactobacillus
  • [#Vaginally delivery] - Gamma aminobutyrate (#GABA), a major CNS inhibitory neurotransmitter, is produced from Lactobacillus and is the first bacterium that is colonized with most vaginally born infants.
  • [1.167] [#Diabetes Type 2
    - Lactobacillus > positively correlated with fasting glucose and HbA1c levels > increased insulin resistance.
  • [1.168] [#Fermented food
    Fermented soymilk with various lactic acid bacteria > Reducing the content of phytic acid > Increasing the bioavailability of magnesium, calcium, iron and zinc
  • [1.169] [#Lactoferrin
    - LF > iron donor to support the growth of some bacteria with lower iron demands > Lactobacillus sp. or #Bifidobacterium sp.
  • [1.170] [#Parkinson’s Disease] [#Bifidobacterium adolescentis
    - PD patients, showing an increase in #Akkermansia, Bifidobacterium, and Lactobacillus and a decrease in #Prevotella
  • [1.171] [#Antibiotic Therapy
    - Macrolide exposure was associated with reduced richness for twice as long as penicillin. - Antbiotic at childhud > reduced #Bifidobacteria (5 studies) and Lactobacillus (2 studies), and significant increases in #Proteobacteria such as E. coli (4 studies).
  • [1.158] [#Pancreatic Cancer] [#Indole, #Tryptophan] [#Probiotic
  • [1.136] [#Ulcerative Colitis
    - during active UC, anti-inflammatory Lactobacillus and #Pediococcus acidilactici were absent in fecal samples
  • [1.150] [#Hypertension] [#High salt diet
    - Salt consumption decreased Lactobacillus abundance, which was linked to increased T helper 17 cell numbers in murine small intestinal lamina propria lymphocytes and human peripheral blood lymphocytes, as well as higher blood pressure. - a high-salt diet reduced Lactobacillus abundance, increased proinflammatory gene expression, and exacerbated #Colitis in two separate disease models
  • [1.172] [#Inflamatory bowel disease
    - studies have demonstrated striking differences between luminal and mucosal samples within the colon itself, specifically regarding mucosa-associated bacteria such as #Bifidobacterium, Lactobacillus, and #Akkermansia. - the microbial community composition is different between ileal luminal samples from colonic and fecal samples, as well along the length of the colon itself.
  • [1.173
    - #Allicin (diallylthiosulfinate) is a natural food compound with multiple biological and pharmacological functions. - #Allicin treatment significantly improved GM composition and induced the most significant alteration enrichment of #Bifidobacterium and Lactobacillus. - #Allicin-induced GM to HFD mice (AGMT) significantly increased Blautia [short-chain fatty acids (SCFAs)-producing microbiota] and #Bifidobacterium in HFD mice, also increased the SCFAs in the cecum,
  • [1.174] [#Parkinson’s Disease
    - most PD patients (about 70% of patients) develop gastrointestinal disorders such as constipation, dysphagia, and gastroesophageal reflux. Strikingly, these gastrointestinal dysfunctions (particularly constipation and delayed gastric emptying) can be detected up to 20 years prior to PD diagnosis. - reduction in their number of #Prevotellaceae bacteria compared to controls. Strikingly, this alteration was associated with the severity of the motor symptoms. - PD patients may exhibit not only a decreased abundance of Prevotella but also an increased abundance of Lactobacilliceae. - These alterations may be associated with reduced levels of #Ghrelin, an important gut hormone involved in the survival and efficacy of dopaminergic neurons.
  • [1.175] [#Natural Skin Microbiome] [#Gender
    - female genital tract is characterized by a predominance of Lactobacillus.
  • [1.142] [#Culinary herbs and spices
    - six of seven aqueous culinary spice extracts of oregano, ginger, rosemary, cinnamon, black pepper and cayenne pepper were able to promote the growth of #Bifidobacterium spp. in vitro, whereas turmeric was not. - stimulation of Lactobacillus spp. and inhibition of certain #Clostridium spp. by all seven spices. - increase in most #Clostridium spp. after turmeric and curcumin intervention in a human study.
  • - high consumption compared to low consumption of #Cocoa derived flavanols, significantly stimulated growth of #Bifidobacterium spp. and Lactobacillus spp.
  • [1.176
    - the genus Lactobacillus are also “psychobiotics” and can modulate the gut–brain connection via neuroactive molecules (GABA, glutamate)
  • [1.56] [#Parkinson’s Disease
    - #Bifidobacterium and Lactobacillus species, which are common constituents of commercial probiotics, were more abundant in PD than NHC metagenomes.

Common References