Disease
Microbiota ☳
Metabolome
Factor
Lactobacillaceae ⇒ Lactobacillus {10000118}
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Definition: Lactobacillus
Details
Initialisation date: 2019-06-23
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Enzyme: [ ]
Function: [ ]
Notes:
- Lactubacillus are reduced in chronic stress conditions, Can Lactobacillus probiotics relieve chronic stress?
Shared Reference Notes
[1.1 ] - Two species from Lactobacillus genus ( Lactobacillus johnsonii, Lactobacillus gasseri) act upon mitochondria in the liver leading to the improvement of lipid metabolism.
- Metabolomics analyses revealed that reduced glutathione may mediate these effects.
- The mice receiving those Lactobacilli also had a lower fat mass index than those fed only a western diet
[1.2 ] - The glutamate decarboxylase gen in some LAB strains is a potential GABA producer.
- There are varying levels of inhibition against fungi, with Lactiplantibacillus plantarum and Lentilactobacillus parabuchneri exhibiting the highest suppression against the some strains of Fusarium, Aspergillus, and Penicillium.
- The antifungal activity is mainly due to the activity of acids produced by LAB.
- The antibacillus activity reveals a high inhibition potential of the majority of LAB isolated from sourdough against some strains of Bacillus.
[1.3 ] - Lactobacillus can resist the antimicrobial activity of bile salts.
[1.4 ] - Smectite clay promotes lactic acid bacteria (LABs) to form biofilms on its surface
- Smectite with LABs inhibits tumor growth in mice
- Smectite with LABs enhances anti-#Cancer chemo/immunotherapy in mice
- Smectite with LABs activates dendritic cells via TLR2 signaling
[1.5 ] [#Probiotic (Bifidobacter and Lactobacilus) ] - The administration of a probiotic cocktail, composed of Lactobacillus rhamnosus and Lactobacillus helveticus, reduced the symptoms of #Depression and anxiety
- Following an extremely stressful period, fewer species of Lactobacillus are present in the stool.
- Lactobacillus can produce #Acetylcholine
- Lactobacillus can produce #GABA
[1.6 ] [#Polycystic ovary syndrome ] - Lactobacillus given to letrozole-treated (induces PCOS) rats reduced androgen levels, improved estrous cyclicity, normalized ovarian morphology, as well as increased Lactobacillus and #Clostridium species and decreased #Prevotella .
[1.7 ] - A diet rich in salt (i.e. #High salt diet , or HSD) for instance, can result in depletion of the gut bacteria Lactobacillus spp., which results in T helper cell-mediated immune dysregulation and cognitive dysfunction.
- A diet rich do not increase the serum concentration of proinflammatory molecules.
- Adult male offspring from HSD-fed mice show hyperactivity, reduced sociability and increased repetitive behaviors
[1.8 ] [#Fermented food ] - The excellent biological activities of these functional foods, such as anti-inflammatory and immunomodulatory functions, are widely attributable to their high antioxidant content and lactic acid-producing bacteria
[1.9 ] - #Acetylcholine is produced from Lactobacillus
[#Vaginally delivery ] - Gamma aminobutyrate (#GABA ), a major CNS inhibitory neurotransmitter, is produced from Lactobacillus and is the first bacterium that is colonized with most vaginally born infants.
[#Diabetes Type 2 ] - Lactobacillus > positively correlated with fasting glucose and HbA1c levels > increased insulin resistance.
[1.11 ] [#Fermented food ] Fermented soymilk with various lactic acid bacteria > Reducing the content of phytic acid > Increasing the bioavailability of magnesium, calcium, iron and zinc
[1.12 ] [#Lactoferrin ] - LF > iron donor to support the growth of some bacteria with lower iron demands > Lactobacillus sp. or #Bifidobacterium sp.
[1.13 ] [#Parkinson’s Disease ] [#Bifidobacterium adolescentis ] - PD patients, showing an increase in #Akkermansia , Bifidobacterium, and Lactobacillus and a decrease in #Prevotella
[1.14 ] [#Antibiotic Therapy ] - Macrolide exposure was associated with reduced richness for twice as long as penicillin.
- Antbiotic at childhud > reduced #Bifidobacteria (5 studies) and Lactobacillus (2 studies), and significant increases in #Proteobacteria such as E. coli (4 studies).
[1.15 ] [#Pancreatic Cancer ] [#Indole , #Tryptophan ] [#Probiotic ]
[1.16 ] [#Ulcerative Colitis ] - during active UC, anti-inflammatory Lactobacillus and #Pediococcus acidilactici were absent in fecal samples
[1.17 ] [#Hypertension ] [#High salt diet ] - Salt consumption decreased Lactobacillus abundance, which was linked to increased T helper 17 cell numbers in murine small intestinal lamina propria lymphocytes and human peripheral blood lymphocytes, as well as higher blood pressure.
- a high-salt diet reduced Lactobacillus abundance, increased proinflammatory gene expression, and exacerbated #Colitis in two separate disease models
[1.18 ] [#Inflamatory bowel disease ] - studies have demonstrated striking differences between luminal and mucosal samples within the colon itself, specifically regarding mucosa-associated bacteria such as #Bifidobacterium , Lactobacillus , and #Akkermansia .
- the microbial community composition is different between ileal luminal samples from colonic and fecal samples, as well along the length of the colon itself.
[1.19 ] - #Allicin (diallylthiosulfinate) is a natural food compound with multiple biological and pharmacological functions.
- #Allicin treatment significantly improved GM composition and induced the most significant alteration enrichment of #Bifidobacterium and Lactobacillus .
- #Allicin -induced GM to HFD mice (AGMT) significantly increased Blautia [short-chain fatty acids (SCFAs)-producing microbiota] and #Bifidobacterium in HFD mice, also increased the SCFAs in the cecum,
[#Parkinson’s Disease ] - most PD patients (about 70% of patients) develop gastrointestinal disorders such as constipation, dysphagia, and gastroesophageal reflux. Strikingly, these gastrointestinal dysfunctions (particularly constipation and delayed gastric emptying) can be detected up to 20 years prior to PD diagnosis.
- reduction in their number of #Prevotellaceae bacteria compared to controls. Strikingly, this alteration was associated with the severity of the motor symptoms.
- PD patients may exhibit not only a decreased abundance of Prevotella but also an increased abundance of Lactobacilliceae.
- These alterations may be associated with reduced levels of #Ghrelin , an important gut hormone involved in the survival and efficacy of dopaminergic neurons.
[1.21 ] [#Natural Skin Microbiome ] [#Gender ] - female genital tract is characterized by a predominance of Lactobacillus .
[1.22 ] [#Culinary herbs and spices ] - six of seven aqueous culinary spice extracts of oregano, ginger, rosemary, cinnamon, black pepper and cayenne pepper were able to promote the growth of #Bifidobacterium spp. in vitro, whereas turmeric was not.
- stimulation of Lactobacillus spp. and inhibition of certain #Clostridium spp. by all seven spices.
- increase in most #Clostridium spp. after turmeric and curcumin intervention in a human study.
- high consumption compared to low consumption of #Cocoa derived flavanols, significantly stimulated growth of #Bifidobacterium spp. and Lactobacillus spp.
[1.23 ] - the genus Lactobacillus are also “psychobiotics” and can modulate the gut–brain connection via neuroactive molecules (GABA, glutamate)
[1.24 ] [#Parkinson’s Disease ] - #Bifidobacterium and Lactobacillus species, which are common constituents of commercial probiotics, were more abundant in PD than NHC metagenomes.
[1.25 ] [#Parkinson’s Disease ] - PD > increased relative abundance of family Enterobacteriaceae, genera #Akkermansia , Lactobacillus , #Bifidobacterium .
- PD > decreased relative abundance of family #Lachnospiraceae , #Faecalibacterium
[1.26 ] [#Polyphenol-rich supplementation ] - Polyphenols supplementation significantly increase the Lactobacillus by 220% and #Bifidobacterium by 56% (mostly anthocyanins). -
[1.27 ] - it seems to exist a negative correlation between Lactobacillus and #Bifidobacterium counts with #Sleep and cortisol levels respectively
[#Bipolar disorder , #Major depressive disorder , #Schizophrenia ] - Gut microbiota in BD, MDD and SZ > increase in #Eggerthella and Lactobacillus , together with a decrease in #Coprococcus was common for the three conditions in comparison to controls.
[1.28 ] [#Vaginal microbiota , #Vulvovaginal candidiasis ] [#Candida albicans ] - Lactobacillus spp. produces lactic and other organic acids that contribute to the low pH within the vaginal cavity.
- Low pH (< 4.5) inhibits C. albicans yeast-to-hypha transition.
[1.29 ] [#High-protein diet ] - Excessive protein intake > causing the growth of protein fermenting bacteria as #Clostridium , #Desulfovibrio , #Peptostreptococcus , #Acidaminococcus , #Veillonella , #Propionibacterium , Bacillus, #Bacteroides , #Staphylococcus , and other species of the #Proteobacteria family, and the loss of carbohydrate fermenting bacteria such as #Bacteroides , Lactobacillus , #Bifidobacterium , #Prevotella , #Ruminococcus , #Roseburia , and #Faecalibacterium .
[#Infants ] - Bacterial genera commonly found in the infant small intestine include Lactobacillus , #Clostridium , #Staphylococcus , #Streptococcus , #Bacteroides , and #Bifidobacterium
[#Infants ] Greater proportions of #Palmitic acid in the pool of triacylglycerides, for instance > higher levels of fecal Lactobacillus and #Bifidobacterium in neonates.
- #Oleic acid is beneficial for Lactobacillus spp.
[1.31 ] [#Rheumatoid Arthritis ] - overabundance of #Prevotella copri in early RA patients
- proliferation of the genus Collinsela and some Lactobacillus species.
- Three mechanisms by which microbiota may contribute to RA pathogenesis were proposed: inflammatory responses (#Prevotella copri and Lactobacillus ), molecular mimicry (#Prevotella copri ) and loss of intestinal barrier integrity (#Collinsella ).
[1.32 ] - good immunological and metabolic health-related bacteria, such as #Akkermansia , #Christensenellaceae , and Lactobacillus , were higher in #Centenarians than in other groups
[#Aging ] - the loss of Lactobacillus and #Faecalibacterium , as well as the abundance of #Oscillibacter and #Alistipes genera along with the #Eubacteriaceae family is linked to #Frailty in elderly people.
[1.33 ] - #Bifidobacteria and Lactobacillus spp. can produce micromolar concentrations of #GABA .
- #Grape seed > the growth of Lactobacillus and #Enterococcus spp. were elevated.
- These changes in the gut microbiota were associated with increases in #4-hydroxyphenylacetic acid , #Phenylpropionic acid , #Phenylacetic acid and #4-hydroxybenzoic acid
- #Ferulic acid is a #Hydroxycinnaminic acid produced as a microbial metabolite from several Lactobacillus species and the production of many of its bioactive metabolic products (#Dihydroferulic acid or #Vanillic acid ) is dependent on the gut microbiota.
[1.34 ] [#Anorexia nervosa ] - At the genus level, elevated Lactobacillus counts were observed in the AN microbiota.
[1.35 ] - increased diversity of #Vaginal microbiota and reduced abundance of Lactobacillus spp. contribute to #HPV acquisition, persistence, and development of #Cervical cancer .
[1.36 ] - in neurodegenerative disease > The microbes with elevated populations, like #Bilophila , Butryicicoccus, #Alistipes , #Enterococcus , Lactobacillus , #Streptococcus , #Shigella , and #Desulfovibrio , have the metabolic capability to produce #Putrescine majorly by the #Putrescine III biosynthesis pathway.
- In neurodegenerative diseases > #Histamine and other important #Neurotransmitters were synthesized in reduced amounts by the microbes with an elevated population in the diseased state.
- Most of the microbes, except #Desulfovibrio , Lactobacillus , and #Streptococcus , showed no annotation in their #Genome to synthesize #Histamine .
- #Enterococcus and Lactobacillus had the highest PS for #Butyrate formation through the fermentation of #Pyruvate .
- in neurodegenerative disease > #Shigella , Lactobacillus , and #Streptococcus are such microbes with elevated populations and the highest PS for the #Putrescine III biosynthetic pathway.
[1.37 ] [#Natural Small intestine Microbiome ] [#Escherichia coli ] - At the genus level, bacteria highly abundant in the SI include Lactobacillus , #Veillonella , #Streptococcus , #Gemella , #Actinomyces , and E. coli.
[#Natural Small intestine Microbiome ] - Only select bacteria, including #Clostridium , Lactobacillus , and #Enterococcus species, are able to penetrate, or attach to, the mucus layer at the epithelium and use the mucus as an energy source
[1.38 ] [#humanized Galactooligosaccharides ] - Lactobacillus and #Bifidobacterium specialize in oligosaccharide fermentation, utilizing galactooligosaccharides (GOS), #Fructooligosaccharides (FOS), and #Polysaccharide #Inulin
[1.39 ] [#Bladder cancer ] [#Lactobacillus crispatus ] - Lactobacillus spp were significantly enriched in the #BCG responders. Co-culture with increasing concentrations of Lactobacillus crispatus resulted in increased #BCG -GFP internalization in UCC when compared to controls
[#Short peptide bacteriocins ] - #Lactocillin , a thiopeptide SPB isolated from a vaginal commensal lactobacillus was shown to inhibit several pathogens colonising skin or vagina and showed no antimicrobial activity against other #Lactobacilli species
[1.41 ] [#Cognitive impairment , #Mild Cognitive Impairment ] [#Bacteriophage ] - higher abundance of Lactobacillus phages (family #Siphoviridae of the order #Caudovirales positively associated with better cognitive function; and transplantation of these phages from humans to mice and Drosophila showed increased memory scores and upregulation of memory-involved brain genes.
[1.42 ] - Extra-virgin #Olive oil ingestion in rodents also can promote the growth of certain types of beneficial #Bacteria including species of Lactobacillus , #Bifidobacterium , #Bacteroides , and #Clostridium , and members of the Erysipelotrichaeae.
[#Short Chain Fatty Acid ] [#Olive ] - SCFAs, produced by a number of bacteria, such as #Bacteroides and Lactobacillus , which are often elevated with EVOO consumption, are also potent activators for GPR43
- Lactobacillus to lower plasma #Cholesterol levels may be due partly to the enhanced #Bile Salt hydrolase activity this genus exhibits, as well as the ability to convert #Cholesterol to #Coprostanol , both leading to an impairment of #Cholesterol absorption in the intestine.
[#Olive ] - Lactobacillus , also elevated with EVOO consumption25,29 when administered in #Probiotic form, promoted a significant reduction in plasma total #Cholesterol levels in mice as well as human patients with hypercholesterolemia.
[#Obesity ] [#Olive ] - in humans, EVOO has prebiotic effects, promoting the growth of beneficial bacteria such as Lactobacillus and #Bifidobacterium . Specifically, a #Mediterranean diet supplemented with 40 g/day EVOO for 3 months administered to 18 overweight/obese participants resulted in significantly increased levels of #Lactic acid bacteria compared to baseline.
[1.43 ] [#Polysaccharide ] - #Cessation of breastfeeding initiates the transition towards an #Adult -like gut microbiome composition, which is characterized by expansion of #Roseburia spp. and #Anaerostipes spp., restriction of Lactobacillus spp. and a functional shift towards an increased capacity to degrade complex polysaccharides
[1.44 ] [#Celiac Disease ] - #Bacillus subtilis LZU-GM was isolated from Pakistani traditional fermented sourdough and could degrade 73.7% of #Gluten in 24 h in vitro.
- The #Gluten degradation was 3-fold higher in the small intestine of the strain LZU-GM treated mice group.
- #Gluten -treated mice established positive antigliadin antibodies (AGA) in serum (IgA, IgG, and anti-TG2 antibodies) as compared to the strain LZU-GM treatment group.
- the number of IFN-γ, TNF-α, #IL-10 , and COX-2 cells decrease in the lamina propria of the strain LZU-GM treatment group.
- Microbial community bar plot analysis showed that Lactobacillus , #Dubosiella , and #Enterococcus genera were restored and stabilized in the LZU-GM treatment group while #Blautia and #Ruminococcus were found lower.
[1.45 ] - The #Firmicutes phylum comprises Gram-positive bacteria with low G + C DNA content and is composed of more than 200 different genera, such as Lactobacillus , #Bacillus , #Clostridium , #Enterococcus , and Ruminicoccus.
[#Diabetes Type 1 ] - Studies have reported an increased quantity of #Villanella , #Clostridium , and #Bacteroides and a decreased quantity of Lactobacillus , #Eubacterium rectale , #Blautia coccoides , and #Bifidobacterium in #Children with type 1 diabetes.
- #Diabetes Type 1 > negative correlation has been reported between plasma #Glucose level and #Bifidobacterium , Lactobacillus spp., and #Firmicutes and #Bacteroidetes spp., while there has been positive correlation between #Clostridium and plasma #Glucose level.
[1.46 ] [#Non-alcoholic fatty liver disease ] - #Dorea , Lactobacillus and #Megasphaera are enriched in MAFLD group.
[1.47 ] [#Candida albicans , #Streptococcus mutans ] - The presence of C. albicans would increase the abundance of #Streptococcus (particularly S. mutans), certain Lactobacillus species, and salivary #Veillonella and #Prevotella , and also increase the cariogenic virulence of biofilms
[1.48 ] [#Postmenopausal osteoporosis ] - the enrichment Lactobacillus sp. in non-PMO and the increased abundances of #Peptoniphilus sp., #Propionic acid bacteria, and members of the #Galicola genus in PMO
[1.49 ] - #Leptin serum level was positively correlated with the abundance of #Bifidobacterium and #Lactobacillus whereas #Leptin serum level was negatively correlated with #Clostridium , #Bacteroides and, #Prevotella
[#Postmenopausal ] - Gut #Bacteria that possess β-glucuronidase and/or β-galactosidase activity can metabolize #Estrogen including #Bifidobacterium , #Faecalibacterium , Lactobacillus , #Veillonella
[#Diabetes Type 2 , #Peripheral neuropathy ] [#Sphingomyelin ] [#High Fat Diet ] - Lactobacillus , #Lachnoclostridium , and #Anaerotruncus taxa variants positively correlated with several lipid species, particularly elevated plasma sphingomyelins and sciatic nerve triglycerides.
[#Peripheral neuropathy ] - Lactobacillus , #Lachnoclostridium , and #Anaerotruncus , correlated negatively with several free fatty acid and complex lipid species, including LysoPC 16:1, in both plasma and sciatic nerve.
[1.51 ] [#Systemic lupus erythematosus ] - Lactobacillus treatment decreased #IL-6 and increased #IL-10 production in the gut contributing to an anti-inflammatory environment.
[1.52 ] [#Colorectal cancer ] [#Short Chain Fatty Acid ] [#Zizyphus jujuba cv. Muzao ] -ZMP consumption prevented CRC mouse colon shortening, decreased their mortality, reduced pro-inflammatory cytokines, increased the concentration of total short-chain fatty acids (SCFAs) and modulated gut microbiota in their feces.
- ZMP also increased the richness of #Bifidobacterium , #Bacteroides and Lactobacillus .
[1.53 ] - 60 bacterial genera from human gut microbiota (#Bacteroides , #Bifidobacterium , #Escherichia , #Faecalibacterium , and Lactobacillus ,) > encode β-glucuronidase and/or β-galactosidase > impacting endogenous #Estrogen metabolism
[1.54 ] - certain #Bifidobacterium , #Bacteroides , and Lactobacillus species that have high activities of #Bile Salt hydrolase, the enzyme responsible for the deconjugation of #Bile Acids .
[1.55 ] - Lactobacillus spp., which was prevalent in healthy controls’ microbiota, splitted #Gluten peptides, thus reducing their immunogenicity
[1.56 ] [#Spondyloarthritis ] - significant increases in the class #Bacilli , order #Lactobacillales , families #Lactobacillaceae and #Clostridiaceae , and genera Lactobacillus and #Clostridium in non-colonized SpA patients.
[1.57 ] [#Alzheimer’s disease ] - In AD > Gavage with Lactobacillus and #Bifidobacterium restored these changes in the wild-type mice.
[1.58 ] [#Escherichia coli ] - #Vitamin B12 supplementation in mice significantly decreased #Parabacteroides and Lactobacillus and increased E. coli and #Enterococcus abundances in a murine model of #Colitis
[1.59 ] [#Attention Deficit Hyperactivity Disorder ] - Lactobacillus and #Bifidobacterium producers of #GABA , which is known to decrease in patients with ADHD > Ameliorate ADHD
[#Autism ] - the levels of #Bifidobacterium (known as beneficial bacteria, such as Lactobacillus species) were significantly lower in the stool of #Children with ASD
- After probiotic supplementation, there was a significant increase in the colony counts of #Bifidobacterium and Lactobacillus with significant improvement in the severity of ASD and gastrointestinal symptoms.
- Lactobacillus species produce #Acetylcholine and #GABA
- enterobacterial metabolite #Norharman , which was partly exogenous and generated from #Tryptophan metabolism regulated by Lactobacillus , showed the strongest inhibitory effect on M1 macrophage activation.
- As a neuroactive β-carboline, #Norharman is a pyridoindole alkaloid that is naturally occurring, is plant-derived or in thermally processed foods, and is formed by the condensation of indoleamine (such as #Tryptamine ) and formaldehyde, showing antioxidant, anti-inflammatory, and antitumor activities
[1.61 ] [#Flavonoid ] - flavanols can stimulate #Lactic acid bacteria.
[1.62 ] - Gut bacteria, specifically of the genera #Bifidobacterium , #Clostridium , and Lactobacillus , can produce enzymes such as β-glucuronidases that modify excreted estrogens, causing them to be retained in the body via reabsorption into circulation. This leads to increased #Estrogen levels which can cause several hormone-linked diseases.
[1.63 ] - Some oral bacteria belonging to genera Lactobacillus , #Lactococcus , #Bifidobacterium , #Streptococcus , #Leuconostoc , and #Pediococcus produce #Lactic acid
[1.64 ] - patients with #Celiac Disease showed the abundance of #Streptococcus , Lactobacillus , #Veillonella , and #Allisonella species, while the abundance of #Ruminococcus , #Faecalibacterium , #Blautia , #Gemmiger , and #Anaerostipes was decreased.
[1.65 ] - #Ginger essential oil supplementation in PL mice enhanced the relative abundance of Lactobacillus , #Alistipes , and #Olsenella , which are considered beneficial bacteria.
[#Non-alcoholic fatty liver disease ] - Lactobacillus may be used as a #Probiotic to improve #Steatohepatitis through the gut microbiota–liver axis by modulating gut microbiota composition and the inflammatory pathway in NAFLD
[1.66 ] - Although 5-aminosalicylates affect the host gut pH and promote the growth of #Bifidobacterium and Lactobacillus , and #Wheat consumption has also been linked to their enrichment.
[#Genome ] - In addition to #Bifidobacterium and Lactobacillus , our study found a significant enrichment of #Streptococcus , a #Lactic acid -producing bacteria, in patients with #Ulcerative Colitis (UC).
- This is in contrast to the majority of earlier studies from west.
- This increase in #Streptococcus abundance has also been observed in UC patients from different populations.
[#Ulcerative Colitis ] - increased abundance of #Nitrate -reducing bacteria in UC patients.
- persistent inflammation in UC patients accumulates nonfermentable #Nitrate .
- #Bifidobacterium and Lactobacillus can utilize nonfermentable forms of #Nitrate .
[1.67 ] [#Indole-3-acetic acid ] - Lactobacillus can use #Tryptophan instead of #Glucose as a source of energy, and produce #AHR ligands such as #Indole -3-acetic acid (IAA), #Tryptamine (TA) and 3-methyl #Indole
[1.68 ] - #Sulfur -metabolism pathways were found to be one of the frequent pathways among certain member of #Cancer -increased taxa such as #Aquabacterium , #Bilophila wadsworthia , #Delftia , #Desulfovibrio , #Escherichia coli , #Fusobacterium , #Klebsiella , Lactobacillus , #Morganella , #Odoribacter , and #Proteus .
[1.69 ] [#Bacteroides-Prevotella group , #Ruminococcus gauvreauii ] [#Keto diet ] - The abundance of Ruminococcus_gauvreauii_group, #Bacteroides , #Bifidobacterium , and #Blautia significantly increased, whereas that of Lactobacillus , #Romboutsia , #Facklamia , and #Turicibacter significantly declined in the KD group compared with the ND group.
[#Alzheimer’s disease ] - co-housing wild-type mice with AD transgenic mice or giving them AD transgenic mice feces caused AD-associated gut microbiota dysbiosis, #Tau phosphorylation, and #Cognitive impairment .
- Gavage with Lactobacillus and #Bifidobacterium restored these changes.
[1.71 ] [#Lachnospiraceae ] [#Fiber-free diet ] - The lack of dietary fiber > reduced abundances of the #Butyrate -producing genera Lachnospiraceaea NK4A136 and #Roseburia . Additionally, Lactobacillus , which was also reduced in Fibre deprived mice
[1.72 ] [#Osteopontin ] - OPN could reduce the colonization of Lactobacillus in the intestine of mice and promote the abundance of #Dorea , which could further regulate metabolic disorders
[1.73 ] [#Parkinson’s Disease ] - Lactobacillus and #Bifidobacterium genus were most abundant in PD patients. #Prevotella VZCB and other #Faecalibacterium were most abundant in controls.
[1.74 ] [#Non alcoholic steatohepatitis ] [#Probiotic ] - Probiotics, such as #Bifidobacterium and Lactobacillus strains, have been shown to reduce oxidative and inflammatory liver damage while also decreasing hepatic triglycerides (TG) and hepatic steatosis.
[1.75 ] - Lactobacillus was demonstrated to enhance antigen-specific IgA secretion and induce Tfh cells in mice
[#Primary immune thrombocytopenia ] - fecal bacteria such as #Actinomycetaceae , #Blautia , #Streptococcus , and Lactobacillus are enriched, whereas bacteria such as #Bacteroides are depleted in ITP patients.
[#Primary immune thrombocytopenia ] - lactobacillus might indeed play a key role in the progression of ITP.
[#Primary immune thrombocytopenia ] [#Streptococcus anginosus , #Streptococcus parasanguinis , #Streptococcus salivarius ] - Lactobacillus and #Streptococcus (including S. anginosus, #Streptococcus sp., S. parasanguinis, and S. salivarius) were enriched in ITP patients.
Intervention in Disease [ ]
Author: MetaBiom
Identifier: 10000118
URL: https://www.metabiom.org/microbiota/17/lactobacillus
Keywords: Microbiome, Dysbiosis, Microbiota, Organism, Bacteria
Common References
[1.1 ] Transkingdom interactions between Lactobacilli and hepatic mitochondria attenuate western diet-induced diabetes [2021] [Research] [Nature communications] [Journal] [80001503 ]
[1.2 ] Functional Properties and Sustainability Improvement of Sourdough Bread by Lactic Acid Bacteria [2020] [Research] [Microorganisms] [Journal] [80001555 ]
[1.3 ] Bile resistance mechanisms in Lactobacillus and Bifidobacterium [2013] [Research] [Frontiers in Microbiology] [Journal] [80001642 ]
[1.4 ] Smectite promotes probiotic biofilm formation in the gut for cancer immunotherapy [2021] [Research] [Cell Reports] [Journal] [80001709 ]
[1.5 ] The Contribution of Gut Microbiota–Brain Axis in the Development of Brain Disorders [2021] [Review] [Frontiers in Neuroscience] [Journal] [80001732 ]
[1.6 ] Polycystic Ovary Syndrome and the Gut Microbiome [2021] [Report] [WholeFoods MAGAZIN] [Blog] [80001774 ]
[1.7 ] Altered gut microbiome and autism like behavior are associated with parental high salt diet in male mice [2021] [Review] [Scientific Reports] [Journal] [80001781 ]
[1.8 ] Anti-Inflammatory and Immunomodulatory Properties of Fermented Plant Foods [2021] [Review] [Nutrients] [Journal] [80001873 ]
[1.9 ] Probiotics: A potential immunotherapeutic approach for the treatment of schizophrenia [2019] [Review] [Journal of Pharmacy and BioAllied Sciences] [Journal] [80001875 ]
[1.10 ] Insights into the role of gut microbiota in obesity: pathogenesis, mechanisms, and therapeutic perspectives [2018] [Review] [Protein & Cell] [Journal] [80002107 ]
[1.11 ] Bioaccessibility and Bioavailability of Minerals in Relation to a Healthy Gut Microbiome [2021] [Review] [International journal of molecular sciences] [Journal] [80002142 ]
[1.12 ] The Functional Role of Lactoferrin in Intestine Mucosal Immune System and Inflammatory Bowel Disease [2021] [Review] [Frontiers in nutrition] [Journal] [80002175 ]
[1.13 ] Composition of intestinal flora affects the risk relationship between Alzheimer’s disease/Parkinson’s disease and cancer [2022] [Review] [Biomedicine & Pharmacotherapy] [Journal] [80002199 ]
[1.14 ] Association between antibiotics and gut microbiome dysbiosis in children: systematic review and meta-analysis [2021] [Review] [Gut microbes] [Journal] [80002271 ]
[1.15 ] Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity [2022] [Research] [Immunity] [Journal] [80002298 ]
[1.16 ] The Efficacy of Probiotics, Prebiotic Inulin-Type Fructans, and Synbiotics in Human Ulcerative Colitis: A Systematic Review and Meta-Analysis [2019] [Meta-Analysis] [Nutrients] [Journal] [80002431 ]
[1.17 ] Rethinking healthy eating in light of the gut microbiome [2022] [Review] [Cell Host & Microbe] [Journal] [80002441 ]
[1.18 ] Metabolomics: The Key to Unraveling the Role of the Microbiome in Visceral Pain Neurotransmission [2022] [Review] [Frontiers in Neuroscience] [Journal] [80002461 ]
[1.19 ] Allicin‐induced host‐gut microbe interactions improves energy homeostasis [2020] [The FASEB Journal] [Journal] [80002476 ]
[1.20 ] Nutrition and Gut–Brain Pathways Impacting the Onset of Parkinson’s Disease [2022] [Review] [Nutrients] [Journal] [80002546 ]
[1.21 ] Characteristics of the Skin Microbiome in Selected Dermatological Conditions: A Narrative Review [2022] [Review] [Life] [Journal] [80002602 ]
[1.22 ] Gut microbial modulation by culinary herbs and spices [2023] [Review] [Food Chemistry] [Journal] [80002681 ]
[1.23 ] Shotgun Metagenomics Study Suggests Alteration in Sulfur Metabolism and Oxidative Stress in Children with Autism and Improvement after Microbiota Transfer Therapy [2022] [Study] [International journal of molecular sciences] [Journal] [80002687 ]
[1.24 ] Metagenomics of Parkinson’s disease implicates the gut microbiome in multiple disease mechanisms [2022] [Cohort study] [Nature communications] [Journal] [80002696 ]
[1.25 ] An open label, non-randomized study assessing a prebiotic fiber intervention in a small cohort of Parkinson’s disease participants [2023] [Cohort study] [Nature communications] [Journal] [80002769 ]
[1.26 ] Dietary Polyphenol, Gut Microbiota, and Health Benefits [2022] [Review] [Antioxidants] [Journal] [80002820 ]
[1.27 ] Microbiota–gut–brain axis mechanisms in the complex network of bipolar disorders: potential clinical implications and translational opportunities [2023] [Review] [Molecular Psychiatry] [Journal] [80002837 ]
[1.28 ] The Role of Host and Fungal Factors in the Commensal-to-Pathogen Transition of Candida albicans [2023] [Review] [Current Clinical Microbiology Reports] [Journal] [80002841 ]
[1.29 ] Gut-Muscle Axis Exists and May Affect Skeletal Muscle Adaptation to Training [2020] [Review] [Nutrients] [Journal] [80002842 ]
[1.30 ] The role of human milk fats in shaping neonatal development and the early life gut microbiota [2023] [Review] [Microbiome Research Reports] [Journal] [80002843 ]
[1.31 ] The role of the microbiome in rheumatoid arthritis: a review [2023] [Review] [Rheumatology Advances in Practice] [Journal] [80002845 ]
[1.32 ] How Microbiomes Affect Skin Aging: The Updated Evidence and Current Perspectives [2022] [Review] [Life] [Journal] [80002854 ]
[1.33 ] The Gut Microbiota Links Dietary Polyphenols With Management of Psychiatric Mood Disorders [2019] [Review] [Frontiers in Neuroscience] [Journal] [80002856 ]
[1.34 ] The gut microbiota contributes to the pathogenesis of anorexia nervosa in humans and mice [2023] [Study] [Nature Microbiology] [Journal] [80002863 ]
[1.35 ] The interplay between human papillomavirus and vaginal microbiota in cervical cancer development [2023] [Research] [Virology Journal] [Journal] [80002867 ]
[1.36 ] Comparative in-silico analysis of microbial dysbiosis discern potential metabolic link in neurodegenerative diseases [2023] [Review] [Frontiers in Neuroscience] [Journal] [80002870 ]
[1.37 ] The emerging role of the small intestinal microbiota in human health and disease [2023] [Review] [Gut microbes] [Journal] [80002887 ]
[1.38 ] Gut Microbiome: Profound Implications for Diet and Disease [2019] [Review] [Nutrients] [Journal] [80002909 ]
[1.39 ] PD25-08 THE BLADDER TUMOR MICROBIOME MAY AUGMENT RESPONSE TO BCG IN NON-MUSCLE INVASIVE BLADDER CANCER [2023] [Study] [Journal of Urology] [Journal] [80002930 ]
[1.40 ] Microbial derived antimicrobial peptides as potential therapeutics in atopic dermatitis [2023] [Review] [Frontiers in Immunology] [Journal] [80002951 ]
[1.41 ] Unique trans-kingdom microbiome structural and functional signatures predict cognitive decline in older adults [2023] [Study] [GeroScience] [Journal] [80002973 ]
[1.42 ] Extra-virgin olive oil and the gut-brain axis: influence on gut microbiota, mucosal immunity, and cardiometabolic and cognitive health [2021] [Study] [Nutrition Reviews] [Journal] [80002976 ]
[1.43 ] Gut microbiome immaturity and childhood acute lymphoblastic leukaemia [2023] [Review] [80003007 ]
[1.44 ] A gluten degrading probiotic Bacillus subtilis LZU-GM relieve adverse effect of gluten additive food and balances gut microbiota in mice [2023] [Food Research International] [Journal] [80003030 ]
[1.45 ] Gut Microbiome–Brain Alliance: A Landscape View into Mental and Gastrointestinal Health and Disorders [2023] [Review] [ACS Chemical Neuroscience] [Journal] [80003039 ]
[1.46 ] Characteristics of gut microbiota in patients with metabolic associated fatty liver disease [80003040 ]
[1.47 ] High-Throughput Sequencing of Oral Microbiota in Candida Carriage Sjögren’s Syndrome Patients: A Pilot Cross-Sectional Study [2023] [Study] [Journal of Clinical Medicine] [Journal] [80003046 ]
[1.48 ] Gut microbiota signatures and fecal metabolites in postmenopausal women with osteoporosis [2023] [Gut Pathogens] [Journal] [80003077 ]
[1.49 ] Targeting gut microbiota in osteoporosis: impact of the microbial based functional food ingredients [2024] [Review] [Food Science and Human Wellness] [Journal] [80003111 ]
[1.50 ] Gut microbiota in a mouse model of obesity and peripheral neuropathy associated with plasma and nerve lipidomics and nerve transcriptomics [2023] [Study] [Microbiome] [Journal] [80003115 ]
[1.51 ] Gut microbiota: a newly identified environmental factor in systemic lupus erythematosus [2023] [Review] [Frontiers in Immunology] [Journal] [80003157 ]
[1.52 ] Microbiome-metabolomic analysis of the impact of Zizyphus jujuba cv. Muzao polysaccharides consumption on colorectal cancer mice fecal microbiota and metabolites [2019] [International Journal of Biological Macromolecules] [Journal] [80003193 ]
[1.53 ] Perturbations in gut microbiota composition in patients with polycystic ovary syndrome: a systematic review and meta-analysis [2023] [80003217 ]
[1.54 ] Relationship between Oat Consumption, Gut Microbiota Modulation, and Short-Chain Fatty Acid Synthesis: An Integrative Review [2023] [Nutrients] [Journal] [80003252 ]
[1.55 ] The Role of Gluten in Gastrointestinal Disorders: A Review [2023] [Nutrients] [Journal] [80003268 ]
[1.56 ] Differential gut microbiome in spondyloarthritis patients associated to Blastocystis colonization [2023] [Scientific Reports] [Journal] [80003286 ]
[1.57 ] Transmission of Alzheimer’s disease-associated microbiota dysbiosis and its impact on cognitive function: evidence from mice and patients [2023] [80003288 ]
[1.58 ] B Vitamins and Their Roles in Gut Health [2022] [Microorganisms] [Journal] [80003304 ]
[1.59 ] Psychobiotics and fecal microbial transplantation for autism and attention-deficit/hyperactivity disorder: microbiome modulation and therapeutic mechanisms [2023] [Frontiers in Cellular and Infection Microbiology] [Journal] [80003318 ]
[1.60 ] Tryptophan metabolite norharman secreted by cultivated Lactobacillus attenuates acute pancreatitis as an antagonist of histone deacetylases [2023] [BMC Medicine] [Journal] [80003321 ]
[1.61 ] Prebiotics: Definition, Types, Sources, Mechanisms, and Clinical Applications [2019] [Foods] [Journal] [80003325 ]
[1.62 ] Never fear, the gut bacteria are here: Estrogen and gut microbiome-brain axis interactions in fear extinction [2023] [International Journal of Psychophysiology] [Journal] [80003326 ]
[1.63 ] Role of Oral Microbiota in Cancer Development [2019] [Microorganisms] [Journal] [80003331 ]
[1.64 ] Microbiome Metabolites in Health and Disease [80003332 ]
[1.65 ] Ginger essential oil prevents NASH progression by blocking the NLRP3 inflammasome and remodeling the gut microbiota-LPS-TLR4 pathway [2023] [80003336 ]
[1.66 ] Enrichment of Lactic Acid-Producing Bacteria in the Fecal Microbiota of Patients with Ulcerative Colitis in North India [2023] [Advanced Gut & Microbiome Research] [Journal] [80003339 ]
[1.67 ] Modulation of Immune Responses by Nutritional Ligands of Aryl Hydrocarbon Receptor [2021] [Frontiers in Immunology] [Journal] [80003354 ]
[1.68 ] Reproducible and opposing gut microbiome signatures distinguish autoimmune diseases and cancers: a systematic review and meta-analysis [2022] [Microbiome] [Journal] [80003358 ]
[1.69 ] Ketogenic diet ameliorates attention deficit hyperactivity disorder in rats via regulating gut microbiota [2023] [PLOS ONE] [Journal] [80003382 ]
[1.70 ] Transmission of Alzheimer’s Disease-Associated Microbiota Dysbiosis and its Impact on Cognitive Function: Evidence from Mouse Models and Human Patients [2023] [80003400 ]
[1.71 ] Fiber deprivation and microbiome-borne curli shift gut bacterial populations and accelerate disease in a mouse model of Parkinson’s disease [2023] [80003413 ]
[1.72 ] Functional proteins in breast milk and their correlation with the development of the infant gut microbiota: a study of mother-infant pairs [2023] [Frontiers in Microbiology] [Journal] [80003433 ]
[1.73 ] Dietary quality and the gut microbiome in early-stage Parkinson’s disease patients [2023] [Nutritional Neuroscience] [Journal] [80003439 ]
[1.74 ] Dietary Patterns, Foods, and Nutrients to Ameliorate Non-Alcoholic Fatty Liver Disease: A Scoping Review [2023] [Nutrients] [Journal] [80003456 ]
[1.75 ] Gut Microbiome and Metabolome Were Altered and Strongly Associated With Platelet Count in Adult Patients With Primary Immune Thrombocytopenia [2020] [Frontiers in Microbiology] [Journal] [80003463 ]
[1.76 ] Alterations in the gut microbiota of patients with acquired immune deficiency syndrome [2018] [Journal of Cellular and Molecular Medicine] [Journal] [80000714 ]
[1.77 ] Characterization of intestinal microbiota in alcoholic patients with and without alcoholic hepatitis or chronic alcoholic pancreatitis [2018] [Scientific Reports] [Journal] [80000689 ]
[1.78 ] Gut microbiota compositional and functional fingerprint in patients with alcohol use disorder and alcohol-associated liver disease [2020] [Liver International] [Journal] [80001386 ]
[1.79 ] Mild cognitive impairment has similar alterations as Alzheimer’s disease in gut microbiota [2019] [Alzheimer's & Dementia] [Journal] [80001081 ]
[1.80 ] Dysbiosis of saliva microbiome in patients with oral lichen planus [2020] [BMC Microbiology] [Journal] [80001332 ]
[1.81 ] Microbial communities in the upper respiratory tract of patients with asthma and chronic obstructive pulmonary disease. [2014] [PLOS ONE] [Journal] [80000380 ]
[1.82 ] Fecal microbiota profile in atopic asthmatic adult patients [2018] [European Annals of Allergy and Clinical Immunology] [Journal] [80000672 ]
[1.83 ] Distinct pattern of commensal gut microbiota in toddlers with eczema [2006] [International Archives of Allergy Immunology] [Journal] [80000546 ]
[1.84 ] Gastrointestinal microbiota in children with autism in Slovakia. [2015] [Physiology & Behavior] [Journal] [80000232 ]
[1.85 ] Alterations of gut microbiome in autoimmune hepatitis [2019] [Gut] [Journal] [80001159 ]
[1.86 ] Gut microbial profile in biliary atresia: a case-control study [2019] [Journal of Gastroenterology and Hepatology] [Journal] [80001225 ]
[1.87 ] The intestinal microbiota associated with cardiac valve calcification differs from that of coronary artery disease [2019] [Atherosclerosis] [Journal] [80000915 ]
[1.88 ] Metagenomic investigation of bacteria associated with dental lesions: a cross-sectional study [2020] [Medicina Oral, Patologia Oral y Cirugia Oral] [Journal] [80001389 ]
[1.89 ] Metagenomic and metatranscriptomic analysis of saliva reveals disease-associated microbiota in patients with periodontitis and dental caries [2017] [npj Biofilms and Microbiomes] [Journal] [80000615 ]
[1.90 ] Salivary Gluten Degradation and Oral Microbial Profiles in Healthy Individuals and Celiac Disease Patients. [2017] [Applied and Environmental Microbiology] [Journal] [80000398 ]
[1.91 ] Comositional and functional differences between microbiota and cervical carcinogenesis as identified by shotgun metagenomic sequencing [2019] [Cancers] [Journal] [80000960 ]
[1.92 ] Larger amounts of nitrite and nitrate-reducing bacteria in megaesophagus of Chagas’ disease than in controls. [2007] [Journal of Gastrointestinal Surgery] [Journal] [80000549 ]
[1.93 ] Gut microbiota composition and frailty in elderly patients with Chronic Kidney Disease [2020] [PLOS ONE] [Journal] [80001402 ]
[1.94 ] The lung tissue microbiome in chronic obstructive pulmonary disease. [2012] [American Journal of Respiratory and Critical Care Medicine] [Journal] [80000384 ]
[1.95 ] Alterations of Bacteroides sp., Neisseria sp., Actinomyces sp., and Streptococcus sp. populations in the oropharyngeal microbiome are associated with liver cirrhosis and pneumonia. [2015] [BMC Infectious Diseases] [Journal] [80000609 ]
[1.96 ] Hepatocellular carcinoma is associated with gut microbiota profile and inflammation in nonalcoholic fatty liver disease [2018] [Hepatology] [Journal] [80000791 ]
[1.97 ] Characterization of gut microbiota in hospitalized patients with Clostridium difficile infection [2020] [Current Microbiology] [Journal] [80001410 ]
[1.98 ] Increased rectal microbial richness is associated with the presence of colorectal adenomas in humans. [2012] [The ISME Journal] [Journal] [80000304 ]
[1.99 ] Dysbiosis signatures of gut microbiota in coronary artery disease [2018] [Physiological genomics] [Journal] [80000879 ]
[1.100 ] A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypes [2010] [Gastroenterology] [Journal] [80000284 ]
[1.101 ] Effect of gut microbiota on depressive-like behaviors in mice is mediated by the endocannabinoid system [2020] [Research] [Nature communications] [Journal] [80001488 ]
[1.102 ] Gut dysbiosis and detection of "live gut bacteria" in blood of Japanese patients with type 2 diabetes [2014] [Diabetes Care] [Journal] [80000309 ]
[1.103 ] Metagenomic analysis of duodenal microbiota reveals a potential biomarker of dysbiosis in the course of obesity and type 2 diabetes: a pilot study [2020] [Journal of Clinical Medicine] [Journal] [80001381 ]
[1.104 ] Dysbiosis of urinary microbiota is positively correlated with type 2 diabetes mellitus [2017] [Oncotarget] [Journal] [80000429 ]
[1.105 ] Intestinal microbiota is altered in patients with gastric cancer from Shanxi Province, China [2019] [Digestive Diseases and Sciences] [Journal] [80001028 ]
[1.106 ] Gastric microbial community profiling reveals a dysbiotic cancer-associated microbiota [2018] [Gut] [Journal] [80000711 ]
[1.107 ] Dysbiosis of fecal microbiota and high frequency of Citrobacter, Klebsiella spp., and Actinomycetes in patients with irritable bowel syndrome and gastroenteritis [2016] [Gastroenterology and Hepatology] [Journal] [80000589 ]
[1.108 ] Synchronous genitourinary lichen sclerosus signals a distinct urinary microbiome profile in men with urethral stricture disease [2020] [World Journal of Urology] [Journal] [80001356 ]
[1.109 ] Hepatic glycogen storage diseases are associated to microbial dysbiosis [2019] [PLOS ONE] [Journal] [80001020 ]
[1.110 ] Metagenomic and metabolomic analyses unveil dysbiosis of gut microbiota in chronic heart failure patients [2018] [Scientific Reports] [Journal] [80000686 ]
[1.111 ] Featured gut microbiomes associated with the progression of chronic hepatitis B disease [2020] [Frontiers in Microbiology] [Journal] [80001369 ]
[1.112 ] Intestinal microbiota in patients with chronic hepatitis C with and without cirrhosis compared with healthy controls [2018] [Liver International] [Journal] [80000712 ]
[1.113 ] Altered immunity and microbial dysbiosis in aged individuals with long-term controlled HIV infection [2019] [Frontiers in Immunology] [Journal] [80000974 ]
[1.114 ] Hypertension is associated with intestinal microbiota dysbiosis and inflammation in a Brazilian population [2020] [Frontiers in Pharmacology] [Journal] [80001373 ]
[1.115 ] Distinct nasopharyngeal and oropharyngeal microbiota of children with influenza A virus compared with healthy children [2018] [BioMed Research International] [Journal] [80000961 ]
[1.116 ] Characterization of gut microbiota, bile acid metabolism, and cytokines in intrahepatic cholangiocarcinoma [2019] [Hepatology] [Journal] [80001173 ]
[1.117 ] Comparative analysis of the oral microbiota between iron-deficiency anaemia (IDA) patients and healthy individuals by high-throughput sequencing [2019] [BMC Oral Health] [Journal] [80001259 ]
[1.118 ] Molecular characterization of the intestinal microbiota in patients with and without abdominal bloating [2016] [American journal of physiology. Gastrointestinal and liver physiology] [Journal] [80000352 ]
[1.119 ] Characteristics of the urinary microbiome in kidney stone patients with hypertension [2020] [Journal of Translational Medicine] [Journal] [80001334 ]
[1.120 ] Multiple sclerosis patients have a distinct gut microbiota compared to healthy controls_DUBLICATE [2016] [Scientific Reports] [Journal] [80000891 ]
[1.121 ] Fecal and blood microbial 16S rRNA gene alteration in Chinese patients with multiple system atrophy and its subtypes [2019] [Journal of Parkinson's Disease] [Journal] [80001176 ]
[1.122 ] Microbiome signatures associated with steatohepatitis and moderate to severe fibrosis in children with nonalcoholic fatty liver disease [2019] [Gastroenterology] [Journal] [80001063 ]
[1.123 ] Dysbiosis gut microbiota associated with inflammation and impaired mucosal immune function in intestine of humans with non-alcoholic fatty liver disease [2015] [Scientific Reports] [Journal] [80000572 ]
[1.124 ] Salivary cariogenic bacteria counts are associated with obesity in student women at a Malaysian university [2018] [Asia Pacific Journal of Clinical Nutrition] [Journal] [80000682 ]
[1.125 ] Differences in gut microbiota composition between obese and lean children: a cross-sectional study [2013] [Gut Pathogens] [Journal] [80000241 ]
[1.126 ] Microbial diversity in saliva of oral squamous cell carcinoma [2011] [FEMS Immunology and Medical Microbiology] [Journal] [80000786 ]
[1.127 ] Gut microbiota alterations associated with reduced bone mineral density in older adults [2019] [Rheumatology] [Journal] [80001175 ]
[1.128 ] Gut microbial profile analysis by MiSeq sequencing of pancreatic carcinoma patients in China [2017] [Oncotarget] [Journal] [80000728 ]
[1.129 ] Parkinson’s Disease and Parkinson’s Disease medications have distinct signatures of the gut microbiome. [2017] [Movement Disorders] [Journal] [80000277 ]
[1.130 ] Inflammatory microbes and genes as potential biomarkers of Parkinson’s disease [2022] [Review] [npj Biofilms and Microbiomes] [Journal] [80002678 ]
[1.131 ] Characterization of pelvic and cervical microbiotas from patients with pelvic inflammatory disease [2018] [Journal of Medical Microbiology] [Journal] [80000794 ]
[1.132 ] Obese adolescents with PCOS have altered biodiversity and relative abundance in Gastrointestinal microbiota [2020] [The Journal of Clinical Endocrinology and Metabolism] [Journal] [80001360 ]
[1.133 ] A complete guide to human microbiomes: Body niches, transmission, development, dysbiosis, and restoration [2022] [Review] [Frontiers in Systems Biology] [Journal] [80002487 ]
[1.134 ] Gut microbial profile is altered in primary biliary cholangitis and partially restored after UDCA therapy [2017] [Gut] [Journal] [80000594 ]
[1.135 ] Characterization of intestinal microbiota in ulcerative colitis patients with and without primary sclerosing cholangitis [2016] [Journal of Crohn's and Colitis] [Journal] [80000753 ]
[1.136 ] Primary sclerosing cholangitis is characterised by intestinal dysbiosis independent from IBD [2016] [Gut] [Journal] [80000513 ]
[1.137 ] Alveolar microbiota profile in patients with human pulmonary tuberculosis and interstitial pneumonia [2020] [Microbial Pathogenesis] [Journal] [80001312 ]
[1.138 ] Analysis of fecal lactobacillus community structure in patients with early rheumatoid arthritis [2013] [Current Microbiology] [Journal] [80000537 ]
[1.139 ] Alterations in intestinal microbiota diversity, composition, and function in patients with sarcopenia [2021] [Study] [Scientific Reports] [Journal] [80002671 ]
[1.140 ] Analysis of microbiota in first episode psychosis identifies preliminary associations with symptom severity and treatment response [2018] [Schizophrenia Research] [Journal] [80000754 ]
[1.141 ] Alterations of gut microbiome in the patients with severe fever with thrombocytopenia syndrome [2018] [Frontiers in Microbiology] [Journal] [80000848 ]
[1.142 ] Fecal microbiota signatures of adult patients with different types of short bowel syndrome [2017] [Journal of Gastroenterology and Hepatology] [Journal] [80000662 ]
[1.143 ] Dysbiosis of the buccal mucosa microbiome in primary Sjögren’s syndrome patients [2018] [Rheumatology] [Journal] [80000861 ]
[1.144 ] Saliva microbiome in primary Sjogren’s syndrome reveals distinct set of disease associated microbes [2019] [Oral Diseases] [Journal] [80001246 ]
[1.145 ] Connection between the Gut Microbiome, Systemic Inflammation, Gut Permeability and FOXP3 Expression in Patients with Primary Sjögren’s Syndrome [2020] [Research] [International journal of molecular sciences] [Journal] [80001479 ]
[1.146 ] Dysbiosis in the oral bacterial and fungal microbiome of HIV-infected subjects is associated with clinical and immunologic variables of HIV infection [2018] [PLOS ONE] [Journal] [80000883 ]
[1.147 ] Comparison of the ocular microbiome between chronic Stevens-Johnson syndrome patients and healthy subjects [2020] [Scientific Reports] [Journal] [80001339 ]
[1.148 ] Association of systemic sclerosis with a unique colonic microbial consortium [2016] [Arthritis & Rheumatology] [Journal] [80000333 ]
[1.149 ] Alterations in the gut microbiota and metabolite profiles of thyroid carcinoma patients [2019] [International Journal of Cancer] [Journal] [80000975 ]
[1.150 ] Dysbiosis of gut microbiota with reduced tremethylamine-N-oxide level in patients with large-artery atherosclerotic stroke or transient ischemic attack._DUBLICATE [2015] [Journal of the American Heart Association] [Journal] [80000456 ]
[1.151 ] Analysis of endoscopic brush samples identified mucosa-associated dysbiosis in inflammatory bowel disease [2018] [Journal of Gastroenterology] [Journal] [80000679 ]
[1.152 ] Alterations of mucosal microbiota in the colon of patients with inflammatory bowel disease revealed by real time polymerase chain reaction amplification of 16S ribosomal ribonucleic acid. [2015] [Indian J Med Res] [Journal] [80000597 ]
[1.153 ] The microbiome in urogenital schistosomiasis and induced bladder pathologies [2017] [PLoS Neglected Tropical Diseases] [Journal] [80001012 ]
[1.154 ] Diversity of endocervical microbiota associated with genital Chlamydia trachomatis infection and infertility among women visiting obstetrics and gynecology clinics in Malaysia [2019] [PLOS ONE] [Journal] [80001294 ]
[1.155 ] Gut microbiota alterations in moderate to severe acne vulgaris patients [2018] [The Journal of Dermatology] [Journal] [80001044 ]
[1.156 ] Molecular diagnosis of vaginitis: comparing quantitative PCR and microbiome profiling approaches to current microscopy scoring [2019] [Journal of Clinical Microbiology] [Journal] [80001177 ]
[1.157 ] Temporal and long-term gut microbiota variation in allergic disease: a prospective study from infancy to school age [2019] [Allergy] [Journal] [80001034 ]
[1.158 ] Microbiome-host interplay in atopic dermatitis and psoriasis [2019] [Nature communications] [Journal] [80001261 ]
[1.159 ] Gut microbiota and dietary patterns in children with attention-deficit/hyperactivity disorder [2019] [European Child & Adolescent Psychiatry] [Journal] [80001226 ]
[1.160 ] Altered gut microbiota in Chinese children with autism spectrum disorders [2019] [Frontiers in Cellular and Infection Microbiology] [Journal] [80000976 ]
[1.161 ] Abnormal intestinal permeability and microbiota in patients with autoimmune hepatitis [2015] [International Journal of Clinical and Experimental Pathology] [Journal] [80000353 ]
[1.162 ] Study Of The Gut Microbiome In Egyptian Patients With Autoimmune Thyroid Diseases [2021] [Research] [The International Journal of clinical Practice] [Journal] [80001587 ]
[1.163 ] Comparison of the diversity of the vaginal microbiota in HIV-infected and uninfected women with and without bacterial vaginosis. [2008] [The Journal of Infectious Diseases] [Journal] [80000370 ]
[1.164 ] Molecular analysis of the diversity of vaginal microbiota associated with bacterial vaginosis. [2010] [BMC Genomics] [Journal] [80000373 ]
[1.165 ] Dysbiosis signatures of the microbial profile in tissue from bladder cancer [2019] [Cancer Medicine] [Journal] [80001272 ]
[1.166 ] Urinary microbiota - a potential biomarker and therapeutic target for bladder cancer [2019] [Journal of Medical Microbiology] [Journal] [80001050 ]
[1.167 ] Duodenal and faecal microbiota of celiac children: molecular, phenotype and metabolome characterization. [2011] [BMC Microbiology] [Journal] [80000529 ]
[1.168 ] Lactobacilli Have a Niche in the Human Nose [2021] [Research] [Cell Reports] [Journal] [80001688 ]
[1.169 ] Gut microbiome and serum metabolome analyses identify unsaturated fatty acids and butanoate metabolism induced by gut microbiota in patients with chronic spontaneous urticaria [2020] [Frontiers in Cellular and Infection Microbiology] [Journal] [80001363 ]
[1.170 ] Intestinal floras of populations that have a high risk of colon cancer [1995] [Applied and Environmental Microbiology] [Journal] [80001116 ]
[1.171 ] Alterations of the predominant fecal microbiota and disruption of the gut mucosal barrier in patients with early-stage colorectal cancer [2020] [BioMed Research International] [Journal] [80001354 ]
[1.172 ] Reduced abundance of butyrate-producing bacteria species in the fecal microbial community in Crohn’s Disease. [2016] [Digestion] [Journal] [80000250 ]
[1.173 ] Microbiota profile in new-onset pediatric Crohn’s disease: data from a non-Western population [2018] [Gut Pathogens] [Journal] [80000941 ]
[1.174 ] Cutaneous burn injury modulates urinary antimicrobial peptide responses and the urinary microbiome [2017] [Critical Care Medicine] [Journal] [80000424 ]
[1.175 ] Gut microbiota in children with type 1 diabetes differs from that in healthy children: a case-control study [2013] [BMC Medicine] [Journal] [80000311 ]
[1.176 ] The salivary microbiome is altered in children with eosinophilic esophagitis and correlates with disease activity [2019] [Clinical and Translational Gastroenterology] [Journal] [80001126 ]
[1.177 ] Gallstone Disease and Bacterial Metabolic Performance of Gut Microbiota in Middle-Aged and Older Patients [2022] [Clinical study] [International Journal of General Medicine] [Journal] [80002433 ]
[1.178 ] The placental microbiota is altered among subjects with gestational diabetes mellitus: a pilot study [2017] [Frontiers in Physiology] [Journal] [80000654 ]
[1.179 ] Molecular alteration analysis of human gut microbial composition in Graves’ disease patients [2018] [International Journal of Biological Sciences] [Journal] [80000858 ]
[1.180 ] Molecular estimation of alteration in intestinal microbial composition in Hashimoto’s thyroiditis patients [2017] [Biomedicine & Pharmacotherapy] [Journal] [80000607 ]
[1.181 ] Gut microbiome analysis as a tool towards targeted non-invasive biomarkers for early hepatocellular carcinoma [2018] [Gut] [Journal] [80000859 ]
[1.182 ] Gut microbe analysis between hyperthyroid and healthy individuals_DUBLICATE [2014] [Current Microbiology] [Journal] [80000655 ]
[1.183 ] Altered gut microbiota composition associated with eczema in infants [2016] [PLOS ONE] [Journal] [80000741 ]
[1.184 ] Alterations of microbiota in urine from women with interstitial cystitis [2012] [BMC Microbiology] [Journal] [80000409 ]
[1.185 ] Microbiota profile is different for early and invasive colorectal cancer and is consistent throughout the colon [2020] [Journal of Gastroenterology and Hepatology] [Journal] [80001383 ]
[1.186 ] Functional dysbiosis within the gut microbiota of patients with constipated-irritable bowel syndrome [2012] [Alimentary Pharmacology and Therapeutics] [Journal] [80000623 ]
[1.187 ] Profiling the urinary microbiome in men with calcium-based kidney stones [2020] [BMC Microbiology] [Journal] [80001327 ]
[1.188 ] Possible association of Bifidobacterium and Lactobacillus in the gut microbiota of patients with major depressive disorder [2016] [Journal of Affective Disorders] [Journal] [80000768 ]
[1.189 ] The association between vaginal bacterial composition and miscarriage: a nested case-control study [2020] [BJOG: An International Journal of Obstetrics and Gyneacology] [Journal] [80001270 ]
[1.190 ] Conjuctival dysbiosis in mucosa-associated lyphoid tissue lymphoma [2019] [Scientific Reports] [Journal] [80001109 ]
[1.191 ] Altered gut microbiota in myasthenia gravis [2018] [Frontiers in Microbiology] [Journal] [80000850 ]
[1.192 ] Altered fecal microbiota correlates with liver biochemistry in nonobese patients with non-alcoholic fatty liver disease. [2016] [Scientific Reports] [Journal] [80000569 ]
[1.193 ] Metagenome of gut microbiota of children with nonalcoholic fatty liver disease [2019] [Frontiers in Pediatrics] [Journal] [80001279 ]
[1.194 ] Comparative study of vulva and abdominal skin microbiota of healthy females with high and average BMI [2019] [BMC Microbiology] [Journal] [80000935 ]
[1.195 ] Characterization of microbiota in male infertility cases uncovers differences in seminal hyperviscosity and oligoasthenoteratozoospermia possibly correlated with increased prevalence of infectious bacteria [2018] [American Journal of Reproductive Immunology] [Journal] [80000723 ]
[1.196 ] A case controlled study examining the bladder microbiome in women with overactive bladder (OAB) and healthy controls [2017] [European Journal of Obstetrics & Gynecology and Reproductive Biology] [Journal] [80000805 ]
[1.197 ] Alteration of the fecal microbiota in Chinese patients with Parkinson’s disease [2018] [Brain, Behavior, and Immunity] [Journal] [80000645 ]
[1.198 ] Characteristic gut microbiota and predicted metabolic functions in women with PCOS [2020] [Endocrine Connections] [Journal] [80001274 ]
[1.199 ] Changes in the composition of gut and vaginal microbiota in patients with postmenopausal osteoporosis [2022] [Study] [Frontiers in Immunology] [Journal] [80002530 ]
[1.200 ] Age, menopausal status and the bladder microbiome [2018] [European Journal of Obstetrics & Gynecology and Reproductive Biology] [Journal] [80000804 ]
[1.201 ] Qualitative and semiquantitative analysis of Lactobacillus species in the vaginas of healthy fertile and postmenopausal Chinese women [2012] [Journal of Medical Microbiology] [Journal] [80000503 ]
[1.202 ] Distinct microbiome in pouchitis compared to healthy pouches in ulcerative colitis and familial adenomatous polyposis. [2011] [Inflammatory Bowel Diseases] [Journal] [80000242 ]
[1.203 ] Bronchoalveolar lavage fluid microbiota dysbiosis in infants with protracted bacterial bronchitis [2018] [Journal of Thoracic Disease] [Journal] [80000720 ]
[1.204 ] Tissue-Associated Bacterial Alterations in Rectal Carcinoma Patients Revealed by 16S rRNA Community Profiling [2016] [Frontiers in Cellular and Infection Microbiology] [Journal] [80000432 ]
[1.205 ] Alteration of vaginal microbiota in patients with unexplained recurrent miscarriage [2019] [Experimental and Therapeutic Medicine] [Journal] [80000972 ]
[1.206 ] The bacterial communities of the small intestine and stool in children with short bowel syndrome [2019] [PLOS ONE] [Journal] [80001208 ]
[1.207 ] Association between cigarette smoking and the vaginal microbiota: a pilot study [2014] [BMC Infectious Diseases] [Journal] [80000639 ]
[1.208 ] Alterations in the Genital Microbiota in Women With Spinal Cord Injury [2016] [Original Research] [Journal] [80000468 ]
[1.209 ] Alterations of urinary microbiota in type 2 Diabetes Mellitus with hypertension and/or hyperlipidemia [2017] [Frontiers in Physiology] [Journal] [80000661 ]
[1.210 ] Altered fecal microbiota in paediatric inflammatory bowel disease [2015] [Journal of Crohn's and Colitis] [Journal] [80000564 ]
[1.211 ] The female urinary microbiome: a comparison of women with and without urgency urinary incontinence [2014] [mBio] [Journal] [80000787 ]
[1.212 ] Defining dysbiosis in patients with urolithiasis_DUBLICATE [2019] [Scientific Reports] [Journal] [80000950 ]
[1.213 ] Molecular characterization of fecal microbiota in patients with viral diarrhea. [2011] [Current Microbiology] [Journal] [80000437 ]
[1.214 ] Gut Microbiota-Derived Tryptophan Metabolites Maintain Gut and Systemic Homeostasis [2022] [Research] [Cells] [Journal] [80002575 ]
[1.215 ] Maternal exposures and the infant gut microbiome: a systematic review with meta-analysis [2020] [Review] [Gut microbes] [Journal] [80001848 ]
[1.216 ] Resistant starch type 2 and whole grain maize flours enrich different intestinal bacteria and metatranscriptomes [2022] [Study] [Journal of Functional Foods] [Journal] [80002313 ]
[1.217 ] Beef, Casein, and Soy Proteins Differentially Affect Lipid Metabolism, Triglycerides Accumulation and Gut Microbiota of High-Fat Diet-Fed C57BL/6J Mice [2018] [Review] [Frontiers in Microbiology] [Journal] [80002362 ]
[1.218 ] Separating the Empirical Wheat From the Pseudoscientific Chaff: A Critical Review of the Literature Surrounding Glyphosate, Dysbiosis and Wheat-Sensitivity [2020] [Review] [Frontiers in Microbiology] [Journal] [80001476 ]
[1.219 ] Effects of Heat Stress on Gut Microbiome in Rats [2021] [Research] [Indian Journal of Microbiology] [Journal] [80002087 ]
[1.220 ] Beneficial reconstitution of gut microbiota and control of alpha-synuclein and curli-amyloids-producing enterobacteria, by beta 1,3-1,6 glucans in a clinical pilot study of autism and potentials in neurodegenerative diseases [2021] [Study] [medRXiv] [Journal] [80002371 ]
[1.221 ] Metformin Reduces Aging-Related Leaky Gut and Improves Cognitive Function by Beneficially Modulating Gut Microbiome/Goblet Cell/Mucin Axis [2020] [Research] [The Journals of Gerontology] [Journal] [80000214 ]
[1.222 ] Alterations of the Gut Microbiota in Response to Total Sleep Deprivation and Recovery Sleep in Rats [2022] [Study] [Nature and Science of Sleep] [Journal] [80002274 ]
[1.223 ] Sleep and the Gut Microbiome in Psoriasis: Clinical Implications for Disease Progression and the Development of Cardiometabolic Comorbidities [2020] [Review] [Journal of Psoriasis and Psoriatic Arthritis] [Journal] [80002413 ]
[1.224 ] Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice [2020] [Research] [Science translational medicine] [Journal] [80001430 ]
[1.225 ] Next Generation Microbiome Research: Identification of Keystone Species in the Metabolic Regulation of Host-Gut Microbiota Interplay [2021] [Review] [Frontiers in Cell and Developmental Biology] [Journal] [80002163 ]
[1.226 ] Role of Human Milk Bioactives on Infants’ Gut and Immune Health [2021] [Review] [Frontiers in Immunology] [Journal] [80001660 ]
[1.227 ] Neurotransmitter and Intestinal Interactions: Focus on the Microbiota-Gut-Brain Axis in Irritable Bowel Syndrome [2022] [Review] [Frontiers in Endocrinology] [Journal] [80002354 ]