Microbiome & Chronic Diseases

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Streptococcus ⇒ Lactobacilli {10000318}

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Shared Reference Notes

  • [1.8
    - Some Lactobacilli > produce SCFAs > induce Tregs to modulate gut immune responses > shape the pulmonary immune environment > influence the severity of allergic inflammation.
  • [1.9] [#Iron-deficiency anaemia] [#Iron (ferric)
    - #Consumption of Fe supplements increases > Fe in the large intestine > reducing the amount of lactic acid bacteria (bifidobacteria and lactobacilli) and increasing the entropathogenic Escherichia coli
  • [1.4] [#Exercise training
    - Exercise increases > increase α-diversity and microbial metabolites such as SCFAs. - Exercise > typically reveal increases in commensal taxa such as #Bifidobacterium, Lactobacilli, and #Akkermansia
  • [1.1
    - Lactobacilli can reduce #Acne lesions after daily application on the skin
  • [1.7] [#Chronic Obstructive Pulmonary Disease] [#Indole-3-acetic acid (IAA)
    - In Neutrophil-predominant COPD altered #Tryptophan metabolism in airway lactobacilli is associated with reduced indole-3-acetic acid (IAA), which was in turn linked to perturbed host interleukin-22 signalling and epithelial cell apoptosis pathways. - airway microbiome-derived IAA mitigates neutrophilic inflammation, apoptosis, emphysema and lung function decline, via macrophage–epithelial cell cross-talk mediated by interleukin-22. - Intranasal inoculation of two airway lactobacilli restored IAA and recapitulated its protective effects in mice.
  • - #Anthocyanins promote an increase in beneficial bacteria, including Lactobacilli and #Bifidobacteria, while reducing pathogenic bacteria, including Staphylococcus aureus and Salmonella typhimurium.

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