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Microbiome & Chronic Diseases

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Ruminococcus ⇒ Ruminococcaceae {10000246}

Record Keys


Organism:
Ruminococcus
Parent:

Details


Initialisation date:
2020-09-25

Meta Information


Rank:
Genus
Domain:
Bacteria
Zone:[  ]
Enzyme:[  ]
Function:
Mucin-degrading, Fibrosis-triggering, Pro-inflamatory

Notes:


[  ]

Shared Notes


  • [1.3
    - Greater abundance of Ruminococcus, at genus level > related to higher risk of ALS.
    - Kynurenine > risk factor of ALS.
  • [1.88
    - C tropicalis > induces dysbiosis that involves changes in the presence of mucin-degrading bacteria Akkermansia muciniphila and Ruminococcus gnavus > leading to altered tight junction protein expression with increased intestinal permeability > followed by induction of robust Th1/Th17 responses > lead to an accelerated proinflammatory phenotype in experimental colitic mice.
  • [1.19
    - The fibrosis-triggering microbial populations in the cecum as mucolytic bacteria : the species Mucispirillum schaedleri, the genus Ruminococcus, and the genus Anaeroplasma, and in the ileum, such as the genera Streptococcus and Lactobacillus.
  • [1.85
    - Barley contains abundant soluble beta-glucan fibers
    - Bifidobacterium, Butyricicoccus, Collinsella, Ruminococcus 2, and Dialister were characteristic candidate bacterias of the group that consumed large amounts of barley.
    - The relationship between barley consumption and Bifidobacterium remained after adjusting for disease and dietary habits, and that of Butyricicoccus remained after adjusting for disease.
    - Network and cluster analyses revealed that barley consumption was directly correlated with Bifidobacterium and Butyricicoccus.
  • [1.87
    - patients with psoriasis report a relative reduction in intestinal abundance of Akkermansia, Ruminococcus, or Faecalibacterium genera, which are all comprised of mucin-degrading SCFA-producing commensals.
  • [1.56
    - Ruminococcus spp., another important butyrate producing bacteria, significantly decreased in patients with CGSs from the present study. Some authors recently proposed that these bacteria to be considered markers for distinguishing patients with GSD from healthy controls.

Common References