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Disease ⇒ Hepatocellular cancer {40000356}

Record Keys


Type:
Disease
Definition:
Hepatocellular cancer
Parent:[  ]

Details


Initialisation date:[  ]
Other Terms:
HCC

Meta Information


MedDra ID:
10073071
MedDra Level:
pt
ICD:[  ]
Category:[  ]
Zone:[  ]
Mechanism:[  ]

Notes:


[  ]

References Notes


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Shared Reference Notes


  • [1.9
    - Immune reactivity against E. hirae or B. longum also correlates with robust CD8+ T cell responses and better prognosis in HBV-related hepatocellular carcinoma
  • [1.10
    - hepatocellular carcinoma patients had significantly decreased #Linoleic acid and #Phenol levels in serum and feces, two metabolites that significantly inhibit the growth of hepatocellular carcinoma cells.
  • [1.7
    - Coprococcus and Faecalibacterium were depleted in hepatocellular carcinoma.
  • [1.11
    - #Fusobacterium nucleatum was found to directly interact with TIGIT through the FAP2 protein, with subsequent inhibition of NK cells which have significant anti-tumor properties
  • [1.8] [#Secondary bile acids
    - excessive production of the secondary BA deoxycholic acid triggers the expression of inflammatory and tumorigenic factors in hepatic stellate cells (HSCs), contributing to hepatocellular carcinoma development. Secondary BAs might also activate farnesoid X receptor (FXR) and elevate the risk of developing #Colorectal cancer and hepatocellular carcinoma.

Common References