Disease
Microbiota ☳
Metabolome
Factor
Actinomycetaceae ⇒ Actinomyces {10000308}
Record Keys
Parent:
Definition: Actinomyces
Details
Initialisation date: 2020-10-18
Meta Information
Rank:
Domain:
Enzyme: [ ]
Function: Nitrate-reducing
Notes:
[ ] Shared Reference Notes
[1.1 ] [#Diabetes Type 1 , #Diabetes Type 2 ] - Compared to the levels in non-diabetic individuals, diabetes patients exhibited a higher abundance of #Neisseria , TM7, #Gemella , #Eikenella , #Selenomonas , Actinomyces , #Capnocytophaga , #Fusobacterium , #Aggregatibacter , #Veillonella , and #Streptococcus genera and a lower abundance of Filifactor, Synergistetes, Tannerella, Eubacterium, Porphyromonas, and Treponema genera
[1.2 ] [#Breast cancer ] - Actinomyces and #Veillonella were more abundant in breast tumors of #White Women than in those of Black women.
[1.3 ] [#Atherosclerosis , #Rheumatic Hearth Disease ] [#Porphyromonas gingivalis ] - Oral microbes, including P. gingivalis, Actinomyces , #Streptococcus , and #Treponema denticola , have been confirmed as sources of infected heart valves, atherosclerotic plaques, and rheumatic heart valves
[#Primary sclerosing cholangitis ] [#Roseomonas mucosa , #Streptococcus salivarius ] - Even in the early stages, PSC patients’ stool and mucosa significantly enrich oral pathogenic bacteria such as #Streptococcus , #Veillonella , and Actinomyces (#Streptococcus salivarius is an independent predictor of liver-related three-year mortality)
[1.4 ] [#Natural Small intestine Microbiome ] [#Escherichia coli ] - At the genus level, bacteria highly abundant in the SI include #Lactobacillus , #Veillonella , #Streptococcus , #Gemella , Actinomyces , and E. coli.
[1.5 ] - Anaerobes such as Actinomyces , #Veillonella and #Fusobacterium are less prevalent in Oral mucos and mostly present at subgingival sites
[1.6 ] [#Actinomyces odontolyticus ] - In #Hepatobiliary cancers and metastatic #Melanoma , Actinomyces genus and members (e.g., Actinomyces odontolyticus) are consistently enriched in non-responders, whereas #Faecalibacterium prausnitzii is increased in responders.
[1.7 ] [#Rothia aeria , #Rothia dentocariosa , #Rothia mucilaginosa ] Inhaled Glucocorticoid > Dysbisis > presence of typical oral #Bacteria (#Neisseria spp. and #Streptococcus spp.), alongside with the potentially pathogenic Actinomyces spp. and three different #Rothia species, identified simultaneously: R. aeria, R. dentocariosa, and R. mucilaginosa. >
- Although quadrupled dose of corticoids was discontinued and ulcer healing was observed, the patients required topical therapy for maintained xerostomia.
- Progressive systemic autoimmunity (seronegative Sjögren’s syndrome with major organ involvement) was observed later.
[1.8 ] [#Oral squamous cell carcinoma ] - Oral cancer and epithelial precursor lesions are also linked with bacteria from genera #Fusobacterium , #Veillonella , Actinomyces , #Clostridium , #Haemophilus , and #Enterobacteriaceae
Intervention in Disease [ ]
Author: MetaBiom
Identifier: 10000308
URL: https://www.metabiom.org/microbiota/203/actinomyces
Keywords: Microbiome, Dysbiosis, Microbiota, Organism, Bacteria
Common References
[1.1 ] Advances in the oral microbiota and rapid detection of oral infectious diseases [2023] [Review] [Frontiers in Microbiology] [Journal] [80002747 ]
[1.2 ] Concomitant analyses of intratumoral microbiota and genomic features reveal distinct racial differences in breast cancer [2023] [Study] [npj Breast Cancer] [Journal] [80002831 ]
[1.3 ] Regulatory effects of oral microbe on intestinal microbiota and the illness [2023] [Review] [Frontiers in Cellular and Infection Microbiology] [Journal] [80002875 ]
[1.4 ] The emerging role of the small intestinal microbiota in human health and disease [2023] [Review] [Gut microbes] [Journal] [80002887 ]
[1.5 ] From Pathogenesis to Intervention: The Importance of the Microbiome in Oral Mucositis [2023] [Review] [International journal of molecular sciences] [Journal] [80002983 ]
[1.6 ] Assessing the Performance of a Novel Stool-Based Microbiome Test That Predicts Response to First Line Immune Checkpoint Inhibitors in Multiple Cancer Types [2023] [Cohort study] [Cancers] [Journal] [80003055 ]
[1.7 ] Microbiome Analysis and Pharmacovigilance After Inhaled Glucocorticoid: Oral Dysbiosis With the Isolation of Three Rothia Species and Subsequent Sjögren’s Syndrome [2022] [Frontiers in Pharmacology] [Journal] [80003121 ]
[1.8 ] Role of Oral Microbiota in Cancer Development [2019] [Microorganisms] [Journal] [80003331 ]
[1.9 ] Bile acid homeostasis and intestinal dysbiosis in alcoholic hepatitis [2018] [Alimentary Pharmacology & Therapeutics] [Journal] [80000969 ]
[1.10 ] Drinking alcohol is associated with variation in the human oral microbiome in a large study of american adults [2018] [Microbiome] [Journal] [80000944 ]
[1.11 ] Quantitative metagenomics reveals unique gut microbiome biomarkers in ankylosing spondylitis. [2017] [Genome Biology] [Journal] [80000612 ]
[1.12 ] Aerodigestive dysbiosis in children with chronic cough [2018] [Pediatric Pulmonology] [Journal] [80000729 ]
[1.13 ] Molecular diagnosis of vaginitis: comparing quantitative PCR and microbiome profiling approaches to current microscopy scoring [2019] [Journal of Clinical Microbiology] [Journal] [80001177 ]
[1.14 ] Breast tissue, oral and urinary microbiomes in breast cancer [2017] [Oncotarget] [Journal] [80000875 ]
[1.15 ] Pyrosequencing analysis of oral microbiota in children with severe early childhood dental caries [2013] [Current Microbiology] [Journal] [80000436 ]
[1.16 ] Oral microbiome shifts from caries-free to caries-affected status in 3-year-old Chinese children: a longitudinal study [2018] [Frontiers in Microbiology] [Journal] [80000847 ]
[1.17 ] Carious status and supragingival plaque microbiota in hemodialysis patients [2018] [PLOS ONE] [Journal] [80000880 ]
[1.18 ] The lung microbiome in moderate and severe chronic obstructive pulmonary disease. [2012] [PLOS ONE] [Journal] [80000385 ]
[1.19 ] Alterations of Bacteroides sp., Neisseria sp., Actinomyces sp., and Streptococcus sp. populations in the oropharyngeal microbiome are associated with liver cirrhosis and pneumonia. [2015] [BMC Infectious Diseases] [Journal] [80000609 ]
[1.20 ] Metagenomic analyses of the gut microbiota associated with colorectal adenoma [2019] [PLOS ONE] [Journal] [80001024 ]
[1.21 ] Alterations of the gut microbiota in patients with COVID-19 or H1N1 Influenza [2020] [Clinical Infectious Diseases] [Journal] [80001419 ]
[1.22 ] Reduced abundance of butyrate-producing bacteria species in the fecal microbial community in Crohn’s Disease. [2016] [Digestion] [Journal] [80000250 ]
[1.23 ] Oral microbiome signatures in diabetes mellitus and periodontal disease [2020] [Journal of Dental Research] [Journal] [80001350 ]
[1.24 ] Dysbiosis of urinary microbiota is positively correlated with type 2 diabetes mellitus [2017] [Oncotarget] [Journal] [80000429 ]
[1.25 ] Analysis of the microbiota of black stain in the primary dentition [2015] [PLOS ONE] [Journal] [80001289 ]
[1.26 ] Alterations of gut microbiota and blood lipidome in gestational diabetes mellitus with hyperlipidemia [2019] [Frontiers in Physiology] [Journal] [80001152 ]
[1.27 ] Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum [2019] [Microbiome] [Journal] [80001104 ]
[1.28 ] Gut microbial dysbiosis is associated with altered hepatic functions and serum metabolites in chronic hepatitis B patients [2017] [Frontiers in Microbiology] [Journal] [80000704 ]
[1.29 ] Deep sequencing reveals microbiota dysbiosis of tongue coat in patients with liver carcinoma [2016] [Scientific Reports] [Journal] [80001032 ]
[1.30 ] Intestinal microbiota in Hirschsprung Disease [2018] [Journal of Pediatric Gastroenterology and Nutrition] [Journal] [80000783 ]
[1.31 ] Gut microbiota dysbiosis contributes to the development of hypertension [2017] [Review] [Microbiome] [Journal] [80000033 ]
[1.32 ] Dynamic of the human gut microbiome under infectious diarrhea [2022] [Study] [Current Opinion in Microbiology] [Journal] [80002290 ]
[1.33 ] Distinct nasopharyngeal and oropharyngeal microbiota of children with influenza A virus compared with healthy children [2018] [BioMed Research International] [Journal] [80000961 ]
[1.34 ] Characterization of gut microbiota, bile acid metabolism, and cytokines in intrahepatic cholangiocarcinoma [2019] [Hepatology] [Journal] [80001173 ]
[1.35 ] Nasopharyngeal microbiota in children with invasive pneumococcal disease: identification of bacteria with potential disease-promoting and protective effects [2019] [Frontiers in Microbiology] [Journal] [80000985 ]
[1.36 ] Dysbiosis of fecal microbiota and high frequency of Citrobacter, Klebsiella spp., and Actinomycetes in patients with irritable bowel syndrome and gastroenteritis [2016] [Gastroenterology and Hepatology] [Journal] [80000589 ]
[1.37 ] Local oral and nasal microbiome diversity in age-related macular degeneration [2020] [Scientific Reports] [Journal] [80001340 ]
[1.38 ] Age-specific differential changes on gut microbiota composition in patients with major depressive disorder [2020] [Aging] [Journal] [80001345 ]
[1.39 ] A comparative study of the gut microbiota in immune-mediated inflammatory diseases - does a common dysbiosis exist? [2018] [Microbiome] [Journal] [80000942 ]
[1.40 ] The microflora associated with human oral carcinomas [1998] [Oral Oncology] [Journal] [80000771 ]
[1.41 ] Gut microbiota alterations associated with reduced bone mineral density in older adults [2019] [Rheumatology] [Journal] [80001175 ]
[1.42 ] Tongue coating microbiome data distinguish patients with pancreatic head cancer from healthy controls [2019] [Journal of Oral Microbiology] [Journal] [80001042 ]
[1.43 ] Psoriatic patients have a distinct structural and functional fecal microbiota compared with controls [2019] [The Journal of Dermatology] [Journal] [80001222 ]
[1.44 ] Variations in oral microbiome profiles in rheumatoid arthritis and osteoarthritis with potential biomarkers for arthritis screening [2018] [Scientific Reports] [Journal] [80000809 ]
[1.45 ] Subgingival microbiome of rheumatoid arthritis patients in relation to their disease status and periodontal health [2018] [PLOS ONE] [Journal] [80000881 ]
[1.46 ] Analysis of gut mycobiota in first-episode, drug-naïve Chinese patients with schizophrenia: a pilot study [2020] [Behavioural Brain Research] [Journal] [80001250 ]
[1.47 ] Oral microbial flora of patients with Sicca syndrome [2018] [Molecular Medicine Reports] [Journal] [80001007 ]
[1.48 ] Association between the oral microbiome and brain resting state connectivity in smokers [2019] [NeuroImage] [Journal] [80001075 ]
[1.49 ] Metagenomic analysis of bacterial species in tongue microbiome of current and never smokers [2020] [npj Biofilms and Microbiomes] [Journal] [80001323 ]
[1.50 ] Disordered cutaneous microbiota in systemic lupus erythematosus [2020] [Journal of Autoimmunity] [Journal] [80001253 ]
[1.51 ] Bacteriome and mycobiome associations in oral tongue cancer [2017] [Oncotarget] [Journal] [80001010 ]
[1.52 ] Gut microbiota profile in children affected by atopic dermatitis and evaluation of intestinal persistence of a probiotic mixture [2019] [Scientific Reports] [Journal] [80000949 ]
[1.53 ] Alterations of oral microbiota distinguish children with autism spectrum disorders from healthy controls [2018] [Scientific Reports] [Journal] [80000691 ]
[1.54 ] Analysis of gut microbiota profiles and microbe-disease associations in children with austism spectrum disorders in China [2018] [Scientific Reports] [Journal] [80000826 ]
[1.55 ] Sex-based diverse plaque microbiota in children with severe caries [2020] [Journal of Dental Research] [Journal] [80001351 ]
[1.56 ] Comparison of small gut and whole gut microbiota of first-degree relatives with adult celiac disease patients and controls [2019] [Frontiers in Microbiology] [Journal] [80000986 ]
[1.57 ] The fecal, oral, and skin microbiota of children with Chagas disease treated with benznidazole [2019] [PLOS ONE] [Journal] [80001023 ]
[1.58 ] Dysbiosis of the duodenal mucosal microbiota is associated with increased small intestinal permeability in chronic liver disease [2019] [Clinical and Translational Gastroenterology] [Journal] [80001114 ]
[1.59 ] Community dynamics and the lower airway microbiota in stable chronic obstructive pulmonary disease, smokers and healthy non-smokers. [2016] [Thorax] [Journal] [80000390 ]
[1.60 ] Sputum microbiota in moderate versus severe patients with COPD [2014] [The European Respiratory Journal] [Journal] [80000382 ]
[1.61 ] Metabolomics and 16S rRNA sequencing of human colorectal cancers and adjacent mucosa [2018] [PLOS ONE] [Journal] [80001025 ]
[1.62 ] Chronic obstructive pulmonary disease upper airway microbiota alpha diversity is associated with exacerbation phenotype: a case-control observational study [2019] [Respiratory Research] [Journal] [80001100 ]
[1.63 ] Comparison of oropharyngeal microbiota from children with asthma and cystic fibrosis [2017] [Mediators of Inflammation] [Journal] [80000734 ]
[1.64 ] The salivary microbiome is altered in children with eosinophilic esophagitis and correlates with disease activity [2019] [Clinical and Translational Gastroenterology] [Journal] [80001126 ]
[1.65 ] Microbial and inflammatory-based salivary biomarkers of head and neck squamous cell carcinoma [2018] [Clinical and Experimental Dental Research] [Journal] [80001124 ]
[1.66 ] Microbiomic differences in tumor and paired-normal tissue in head and neck squamous cell carcinomas [2017] [Genome Medicine] [Journal] [80000427 ]
[1.67 ] Helicobacter pylori infection is associated with an altered gastric microbiota in children [2017] [Mucosal Immunology] [Journal] [80000582 ]
[1.68 ] Oral and nasal microbiota in Parkinson’s disease [2017] [Parkinsonism and Related Disorders] [Journal] [80000279 ]
[1.69 ] Gut microbiota in patients with Parkinson’s disease in southern China [2018] [Parkinsonism and Related Disorders] [Journal] [80000788 ]
[1.70 ] Periodontal disease and the oral microbiota in new-onset rheumatoid arthritis [2012] [Arthtitis & Rheumatism] [Journal] [80000389 ]
[1.71 ] Deep sequencing of the oral microbiome reveals signatures of periodontal disease [2012] [PLOS ONE] [Journal] [80001205 ]
[1.72 ] Molecular analysis of oral microflora in patients with primary Sjögren’s syndrome by using high-throughput sequencing [2018] [PeerJ] [Journal] [80001013 ]
[1.73 ] Shared gut, but distinct oral microbiota composition in primary Sjögren’s syndrome and systemic lupus erythematosus [2018] [Journal of Autoimmunity] [Journal] [80000806 ]
[1.74 ] Cigarette smoking modulation of saliva microbial composition and cytokine levels [2018] [International Journal of Environmental Research and Public Health] [Journal] [80000857 ]
[1.75 ] Postnatal exposure to ambient air pollutants is associated with the composition of the infant gut microbiota at 6-months of age [2022] [Cohort study] [Gut microbes] [Journal] [80002582 ]
[1.76 ] Chronic cannabis smoking-enriched oral pathobiont drives behavioral changes, macrophage infiltration, and increases β-amyloid protein production in the brain [2021] [Research] [EBioMedicine] [Journal] [80002130 ]
[1.77 ] Separating the Empirical Wheat From the Pseudoscientific Chaff: A Critical Review of the Literature Surrounding Glyphosate, Dysbiosis and Wheat-Sensitivity [2020] [Review] [Frontiers in Microbiology] [Journal] [80001476 ]
[1.78 ] Isolation and Characterization of Nitrate-Reducing Bacteria as Potential Probiotics for Oral and Systemic Health [2020] [Research] [Frontiers in Microbiology] [Journal] [80000216 ]