MetaBiom
Microbiome & Chronic Diseases

Evidence Based Medicine
Sign in
≡ List 

Disease ⇒ Chronic Obstructive Pulmonary Disease {40000195}

Record Keys


Type:
Disease
Definition:
Chronic Obstructive Pulmonary Disease
Parent:[  ]

Details


Initialisation date:
2021-02-09
Other Terms:
COPD

Meta Information


MedDra ID:
10009033
MedDra Level:
pt
ICD:[  ]
Category:[  ]
Zone:[  ]
Mechanism:[  ]

Notes:


[  ]

References Notes


[  ]

Shared Reference Notes


  • [1.15
    - Lung microbiota differences may contribute to airway dysfunction and airway disease in milder COPD particularly by the dysbiosis of the members of the Streptococcus, Prevotella, Veillonella, Staphylococcus, and Pseudomonas genera.
  • [1.16
    - The oral and pulmonary mycobiomes from controls and participants with COPD were dominated by Candida
    - Malassezia and Sarocladium were also frequently found in pulmonary samples.
  • [1.19
    - BJF administration > increased the abundance of Firmicutes and the ratio of Firmicutes to Bacteroides, raising SCFA levels, including acetate, butyrate, and propionate levels.
    - However, the abundance of Bacteroidetes, Proteobacteria, Spirochaetes, Clostridiaceae, and Treponema decreased.
    - BJF decreased the gene and protein expression of NLRP3, Caspase-1, IL-8, and IL-1β, and increased GPR43 expression.

Common References