Microbiome & Chronic Diseases

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Candida ⇒ Saccharomycetales {10001442}

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Shared Reference Notes

  • [1.15
    - The metabolites of Candida is related with different metabolic pathways, such as amino acid metabolism and biosynthesis, fatty acids metabolism, aromatic compounds degradation, mono and sesquiterpenoid synthesis and carotenoid cleavage
  • [1.16] [#Chronic Obstructive Pulmonary Disease
    - The oral and pulmonary mycobiomes from controls and participants with COPD were dominated by Candida - Malassezia and Sarocladium were also frequently found in pulmonary samples.
  • [1.17
    - There is an expansion of Candida sp. and Rhodotorula sp. in stool samples from US infants that later developed #Atopy.
  • [1.18] [#Crohn’s disease] [#Candida albicans, #Candida glabrata, #Candida tropicalis
    - Candida. A common, although not universal, finding has been an increase, statistically significant or trending, in the relative amount of Candida in the fecal mycobiome of patients with CD from diverse geographic locations. The named species is usually C. albicans, but C. tropicalis and C. glabrata have also been reported.
  • [1.13] [#Adult age
    - Multiple Candida spp. were at higher relative abundance in #Children than adults, while #Malassezia and certain food-associated fungi were lower in #Children.
  • [1.19] [#Fecal Microbiota Transplantation
    - In #Ulcerative Colitis (UC), patients’ mycobiota revealed that those with high levels of Candida were more likely to benefit from FMT treatment. - Amelioration of disease was associated with a decrease in Candida following FMT.
  • [1.7] [#Gastric carcinoma
    - Candida and #Alternaria were enriched in GC, while Saitozyma and Thermomyces were GC-depleted
  • [1.8] [#Helicobacter pylori
    - Streptococcus, Neisseriae, Prevotella, Rothia, Fusobacterium, Veillonella, and Haemophilus are considered the main gastric bacterial genera enriched in #H. pylori-positive individuals. - the overgrowth of Candida species in the stomach has been reported during H. pylori infection, which might result in synergistic effects on the H. pylori pathogenesis.
  • [1.3] [#Colorectal cancer
    - in colon cancers Candida > predictive of metastatic disease and attenuated cellular adhesions. - Candida DNA is enriched in tumors and predictive of reduced survival in GI cancers
  • [#Stomach cancer] - In stomach cancers, high rates of Candida were linked to the expression of pro-inflammatory immune pathways

Common References