Negibacteria ⇒ Verrucomicrobia {10001017}

Shared Reference Notes

• [1.1] [#Lachnospiraceae] 
  - 4 weeks of #Grape powder consumption > significantly increased the alpha diversity index of the gut microbiome > increasing Verrucomicrobia at the phylum level, and a significant increase in #Akkermansia and increase in #Flavonifractor and Lachnospiraceae_UCG-010 > decrease in #Bifidobacterium and #Dialister at the genus level.
• [1.2] [#Alzheimer’s disease] 
  - Decrease in #Bacteroidetes and #Alloprevotella and increase in #Proteobacteria, Verrucomicrobia, #Akkermansia, and #Desulfovibrio > improve short-term memory ability and cognitive level of AD mice
• [1.3] [#Diabetes Type 2] 
  - #Black women, regardless of insulin sensitivity > greater relative abundance of the phylum #Actinobacteria, compared to White women. - #Black women with insulin resistance > four fold higher Verrucomicrobia abundance than White women.
• [1.4] [#Ruminococcaceae] [#High Fat Diet] 
  - HFD > decrease relative abundance of Verrucomicrobia, #Akkermansia , Ruminococcaceae_UCG-014 and #Bifidobacteriaceae
• [#Bifidobacteriaceae, #Ruminococcaceae] [#Moderate Treadmill Exercise] - Exercise > increase the relative abundance of Verrucomicrobia, #Akkermansia and Ruminococcaceae_UCG-014
• [1.5] [#Parkinson’s Disease] 
  - Mucin degrading genus #Akkermansia of the phylum Verrucomicrobia has been widely reported to be significantly abundant in PD by most studies. #Akkermansia and Christensenellaceae may symbiotically play a role in PD pathology and progression
• [1.6] 
  - In acute #Colitis, #Melatonin led to increased clinical, systemic and intestinal inflammatory parameters. - During remission, continued MLT administration delayed recovery, increased TNF, memory effector lymphocytes and diminished spleen regulatory cells. - MLT treatment reduced #Bacteroidetes and augmented #Actinobacteria and Verrucomicrobia phyla in mice feces. - Microbiota depletion resulted in a remarkable reversion of the #Colitis phenotype after MLT administration, including a counter-regulatory immune response, reduction in TNF and colon macrophages. - There was a decrease in #Actinobacteria, #Firmicutes and, most strikingly, Verrucomicrobia phylum in recovering mice. Finally, these results pointed to a gut-microbiota-dependent effect of MLT in the potentiation of intestinal inflammation.
• [1.7] 
  - #Akkermansia muciniphila is a mucus-degrading member of the Verrucomicrobia found in the human GI tract. - A. muciniphila represents from 1 to 4% of the bacterial population in the colon.
• [1.8] 
  - #Propionate is produced by some #Firmicutes, #Bacteroidetes, and Verrucomicrobia, especially #Akkermansia muciniphila
• [1.9] [#Gastric bypass surgery] 
  - Roux-en-Y gastric bypass (RYGB) resulted in clear alteration in composition of gut fungal and bacterial microbiota. - Before surgery, patients had higher levels of #Firmicutes and #Actinobacteria and lower levels of Verrucomicrobia - #Faecalibacterium and #Bifidobacterium showed a decrease after surgery and aerotolerant #Streptococcus was increased postoperatively. - The relative abundance of #Proteobacteria was increased after surgery. - Changes in fungal microbiota composition included decreases in #Candida and #Saccharomyces and increases in #Pichia. - levels of Verrucomicrobia and #Proteobacteria increased after the surgery procedure - Bifidobacteriaceae abundance decreased, whereas Streptococcaceae and Enterobacteriaceae increased after surgery. - RYGB led to increased #Firmicutes and #Actinobacteria phyla but decreased #Bacteroidetes phylum
• - enrichment of #Actinobacteria in patients with #Ankylosing spondylitis, and depletion of #Fusobacteria and Verrucomicrobia

References Notes