Candida ⇒ Candida tropicalis {10000117}

Record Keys

Candida tropicalis


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Shared Reference Notes

  • [1.1] [#Colitis, #Crohn’s disease
    - C. tropicalis > induces dysbiosis that involves changes in the presence of mucin-degrading bacteria #Akkermansia muciniphila and #Ruminococcus gnavus > leading to altered tight junction protein expression with increased intestinal permeability > followed by induction of robust Th1/Th17 responses > lead to an accelerated proinflammatory phenotype in experimental colitic mice.
  • [1.2] [#Crohn’s disease] [#Candida albicans, #Candida glabrata
    - #Candida. A common, although not universal, finding has been an increase, statistically significant or trending, in the relative amount of #Candida in the fecal mycobiome of patients with CD from diverse geographic locations. - The named species is usually C. albicans, but C. tropicalis and C. glabrata have also been reported.
  • [1.3] [#Crohn’s disease
    - depletion of Ca tropicalis in patients with isolated ileal CD compared with patients with colonic involvement
  • [#Crohn’s disease] - patients with CD have much higher abundance of Ca tropicalis compared with their first-degree relatives without CD, - Ca tropicalis induces dysbiosis leading to increased intestinal permeability and induces T helper 1/T helper 17 responses in mice.
  • [#Crohn’s disease] - a marked depletion of Ca tropicalis in those CD patients requiring surgery during disease course.
  • [1.4] [#Cancer
    - #Aspergillus fumigatus, C. tropicalis, and #Acremonium exuviarum, all labelled as “oncogenic fungi”
  • [1.5] [#Attention Deficit Hyperactivity Disorder
    - The abundance of Candida (especially #Candida albicans and and C. tropicalis was significantly increased in ADHD patients compared to the healthy controls. - C. albicans secretions significantly enhanced the permeability of Caco-2 cells.

References Notes

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