Disease ⇒ Gastric carcinoma {40000342}
| Type: | Disease |
|---|---|
| Definition: | Gastric carcinoma |
| Parent: | [ ] |
| Initialisation date: | 2022-01-17 |
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| Other Terms: | [ ] |
| MedDra ID: | 10017758 |
|---|---|
| MedDra Level: | pt |
| ICD: | [ ] |
| Category: | Gastroenterology, Oncology |
| Zone: | [ ] |
| Mechanism: | [ ] |
Notes:
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References Notes
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Shared Reference Notes
- [1.6]
- #Aquabacterium, #Streptococcus and #Lachnospiraceae > predict gastric cancer. - patients with low levels of #Streptococcus and #Lachnospiraceae > more likely to live with gastric cancer without it getting worse. - Patient > more bacterial genes involved in the breakdown of #D-galacturonate > play a key role in the development of gastric cancer - [1.5]
- #Candida and #Alternaria were enriched in GC, while Saitozyma and Thermomyces were GC-depleted - [#Cytomegalovirus] - HCMV was found to be higher in GC tissue than adjacent normal tissues and was implicated as being associated with carcinogenesis and possibly lymphatic metastasis of GC.
- - #EBV integrates its DNA into the host, expresses latent protein, and then impairs methylation of DNA via miRNA under the action of the latent protein, resulting in #EBV-positive gastric cancer.
- [1.10] [#Helicobacter pylori]
- The progression of #Chronic gastritis toward gastric carcinoma has been characterized by the reduction in the Helicobacter genus, overgrowth of opportunistic bacteria, increased apoptosis, necrosis, and collagen production, changes in the cytoskeleton and polarity of the gastric epithelium, and gradual suppression of gastric acidity. - [#Peptic ulcer] [#Helicobacter pylori] - H. pylori has a substantial association with chronic gastritis, gastric ulcer, mucosa-associated lymphoid tissue (MALT) lymphoma, and gastric adenocarcinoma.