Microbiome & Chronic Diseases

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Bifidobacterium breve ⇒ Bifidobacterium {10000631}

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Bifidobacterium breve


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Shared Notes

  • [1.7
    - B. breve is the most commonly isolated infant-type Bifidobacterium species from human milk.
    - B. breve is one of the dominant members of the infant’s gut microbiota, involved in the metabolism of human milk oligosaccharides (HMOs) and the production of vitamins.
  • [1.3
    - Bifidobacterium breve, improves cognition.
    - The improvement of cognitive function reveal an inverse correlation of HbA1c with total RBANS score amelioration after the study only in the probiotic group.
  • [1.8
    - Prob+BBR superior to BBR or Prob alone in improving postprandial total cholesterol (pTC) and low-density lipoprotein cholesterol (pLDLc) levels with decrement of multiple species of postprandial lipidomic metabolites after 3 months follow-up.
    - This effect was linked to the changes of fecal Bifidobacterium breve level responding to BBR alone or Prob+BBR treatment.
    - Four fadD genes encoding long-chain acyl-CoA synthetase > identified in the genome of this B. breve strain, and transcriptionally activated by BBR.
    - The activation of fadD by BBR could enhance FFA import and mobilization in B. breve and diliminish the intraluminal lipids for absorption to mediate the effect of Prob+BBR on PL.

Common References