Bifidobacterium ⇒ Bifidobacterium longum {10000149}
| Parent: | |
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| Definition: | Bifidobacterium longum |
| Initialisation date: | 2020-09-06 |
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| Rank: | Species |
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| Domain: | Bacteria |
| Zone: | [ ] |
| Enzyme: | [ ] |
| Function: | Immunomodulation, Anti-cancer |
Notes:
[ ]
Shared Reference Notes
- [1.1]
B. longum APC1472 supplementation was associated with decreased bodyweight, fat depots accumulation and increased glucose tolerance in HFD-fed mice. - [1.2] [#Infant colic]
- [1.3] [#Selenium] [#Food Minerals]
- Se-enriched Bifidobacterium longum >Biotransformation of inorganic Se into bioactive organic Se > High bioaccessibility of selenomethionine and 98% enteric absorbtion - [1.4]
- #Protein powder consumption > decrease in #Lachnospiraceae, #Roseburia, #Blautia, Synergistales, #Coprococcus, #Lactobacillales, Bacilli, Bifidobacterium longum and #Firmicutes. - #Protein powder consumption > higher abundance of #Bacteroidetes. - [1.5] [#Pediococcus pentosaceus] [#Probiotic]
- [1.6]
- Severe Covid > higher abundance of four microbial species (i.e., #Burkholderia contaminans, #Bacteroides nordii, Bifidobacterium longum, and #Blautia sp. CAG 257), six microbial pathways (e.g., glycolysis and fermentation), and 10 virulence genes > further associated with host immune response. - The abundance of Bu. contaminans > associated with higher levels of inflammation biomarkers and lower levels of immune cells. - human-origin proteins identified from both blood and fecal samples suggested gut barrier dysfunction in #Covid-19 patients. - The circulating levels of #Lipopolysaccharide-binding protein increased in patients with severe illness > associated with circulating inflammation biomarkers and immune cells. - proteins of disease-related bacteria (e.g., B. longum) were detectable in blood samples from patients. - [1.7] [#Human milk oligosaccharides] [#Human breast milk]
- breast fed babies #Bifidobacterium spp. is typically high, than in formula fed babies because #Bifidobacterium longum utilizes fucosylated oligosaccharides which is present in mother’s milk. - [1.8] [#Multiple Sclerosis]
- six species are significantly lower in abundance in MS patients than in controls, three of which have known immunomodulatory properties (Bifidobacterium longum, #Clostridium leptum, #Faecalibacterium prausnitzii) - [1.9] [#Infants]
- B. longum abundance was inversely correlated with #Inosine, a purine metabolite with immunoregulatory properties - [#Bipolar disorder, #Major depressive disorder] [#Bifidobacterium infantis] - the abundance of #Fusobacteriaceae, #Escherichia blattae DSM 4481 and #Klebsiella oxytoca were significantly augmented, whereas the Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 was significantly reduced in BD group compared with MDD group
- [1.11] [#Bifidobacterium infantis] [#Human milk lipids] [#Human breast milk]
- #Gangliosides are not antagonistic to all gastrointestinal microorganisms. - Bifidobacterium can grow in the presence of GM-3 and GD-3 while simultaneously lowering ganglioside levels in vitro. - #Bifidobacterium bifidum is very efficient in removing GD-3 by employing extracellular mechanisms, while Bifidobacterium longum subsp. infantis degrades GM-3 intracellularly, with overall lower glycosidase activity. - [#Bifidobacterium infantis] - #Phosphatidylcholine is a major membrane-forming phospholipid in eukaryotes, with an estimated presence of 15% in the bacterial kingdom. - #Phosphatidylcholine exert a prebiotic function on B. longum subsp. infantis, which, by translating the compound to 1,2-sn-diacylglycerols, affects the regulation of colonic mucus production.
- [1.12] [#Lactobacillus helveticus]
- consum of a mix of psychobiotics (L. helveticus and B. longum) exhibited less #Anxiety and #Depression than controls. - [#Depression] [#Bifidobacterium animalis lactis, #Bifidobacterium bifidum, #Lactobacillus acidophilus] [#humanized Galactooligosaccharides] [#Combination of probiotics and polyphenol-rich prebiotics] - patients were administered a synbiotic containing L. acidophilus, B. bifidum, B. lactis, and B. longum with the prebiotics FOS, GOS and #Inulin. In a subset of patients with depressive symptoms, the synbiotic significantly reduced the depressive score compared to both the #Probiotic-alone and placebo groups, which correlated to an increase in #BDNF serum levels.
References Notes
- (1) [1.35]