Disease ⇒ Cancer ⇒ Lung cancer {40000372}
| Type: | Disease |
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| Parent: | |
| Definition: | Lung cancer |
| Initialisation date: | [ ] |
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| Other Terms: | [ ] |
| MedDra ID: | 10023774 |
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| MedDra Level: | pt |
| ICD: | [ ] |
| Category: | [ ] |
| Zone: | [ ] |
| Mechanism: | [ ] |
Notes:
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Shared Reference Notes
- [1.1]
- A greater abundance of Spirochaetia was associated with lower risk of cancer, and increased levels of Lactobacillales was linked to a heightened risk - [1.2]
- Veillonella, Megasphaera, and Streptococcus > increased in lung cancer patients. - Neisseria, Staphylococcus, and Dialister > higher level in lung cancerous lesions than in normal lung tissues - [1.3] [#Asthma, #Cystic fibrosis, #Pneumonia]
- [1.4]
- every standard deviation increase in #Streptococcus abundance was associated with 1.14 times the risk of lung cancer - [1.5] [#kynurenine, #Tryptophan]
- A high-serum Kyn/Trp ratio is also correlated with a poor prognosis after a PD-1 blockade in lung cancer, #Melanoma and #renal cell carcinomas - [1.6]
- In lung cancer, #Blastomyces was associated with tumor tissues. - [1.7] [#Streptococcus agalactiae, #Streptococcus salivarius]
- For non-small cell lung cancer patients, S. salivarius and S. agalactiae react upon gastrointestinal-derived CD4+ T cells and effectively activate monocytes to secrete higher levels of #IL-6, IL-12 and TNF, or so-called, the Th1- and Th17-skewed cytokines
References Notes
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