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Microbiome & Chronic Diseases

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Staphylococcus aureus ⇒ Staphylococcus {10000114}

Record Keys


Organism:
Staphylococcus aureus
Parent:

Details


Initialisation date:
2020-09-06

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Meta Information


Rank:
Species
Domain:
Bacteria
Zone:[  ]
Enzyme:[  ]
Function:[  ]

Notes:


[  ]

References Notes


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Shared Reference Notes


  • [1.28
    - Staphylococcal bacterial infection and bacterial toxins can trigger an immune response that leads to the production of dietary-antigen-specific IgE antibodies in mice, which are limited to the intestine.
    - Following subsequent oral ingestion of the respective dietary antigen, an IgE- and mast-cell-dependent mechanism induced increased visceral pain.
    -This aberrant pain signalling resulted from histamine receptor H1-mediated sensitization of visceral afferents.
    - Injection of food antigens (gluten, wheat, soy and milk) into the rectosigmoid mucosa of patients with irritable bowel syndrome induced local oedema and mast cell activation.
  • [1.12
    - Staphylococcus aureus > contribute to disease progression
  • [1.4
    - increased abundance of S. aureus with depletion of S. epidermidis and Corynebacterium spp. among AD patients.
    - S. epidermidis, a commensal present on non–inflamed skin, appears to be S. aureus best antagonist.
    - less severe flares of AD had higher counts of S. epidermidis whereas the more severe flares were associated with S. aureus
  • - Staphylococcus hominis, S. lugdunensis and S. epidermidis produce several molecules capable of synergizing the innate antimicrobial response against S. aureus
  • [1.5
    - samples where S. aureus was highly abundant, lower abundances of S. hominis and Cutibacterium acnes were observed. M. osloensis and M. luteus were more abundant in AD.
    - The flexures exhibited lower alpha-diversity and were colonized by S. aureus, accompanied by S. epidermidis in lesions. Malassezia species were absent on the neck in AD.
  • [1.2
    - S. aureus, a dominant species among the family of Staphylococcae, can be 100 times more abundant in AD skin compared to normal healthy skin.
    - AD is associated with a depletion in the coagulase-negative staphylococcal species (CoNS), such as S. epidermidis, S. hominis, and other skin commensal bacterial communities, including Streptococcus salivarius, Propionibacterium, Streptococcus, Acinetobacter, Corynebacterium, Prevotella and Proteobacteria.
    - AD patients exhibit abundant S. aureus in their gut microbiota

Common References