Staphylococcus ⇒ Staphylococcus aureus {10000114}

Record Keys

Staphylococcus aureus


Initialisation date:


Meta Information

Zone:[  ]
Enzyme:[  ]
Function:[  ]


[  ]

Shared Reference Notes

  • [1.1
    - Staphylococcal bacterial infection and bacterial toxins can trigger an immune response that leads to the production of dietary-antigen-specific IgE antibodies in mice, which are limited to the intestine. - Following subsequent oral ingestion of the respective dietary antigen, an IgE- and mast-cell-dependent mechanism induced increased visceral pain. -This aberrant pain signalling resulted from histamine receptor H1-mediated sensitization of visceral afferents. - Injection of food antigens (gluten, wheat, soy and milk) into the rectosigmoid mucosa of patients with #Irritable bowel syndrome induced local oedema and mast cell activation.
  • [1.2] [#Cutaneous T-Cell Lymphoma
    - Staphylococcus aureus > contribute to disease progression
  • [1.3] [#Atopic Dermatitis] [#Staphylococcus epidermidis
    - increased abundance of S. aureus with depletion of S. epidermidis and #Corynebacterium spp. among AD patients. - S. epidermidis, a commensal present on non–inflamed skin, appears to be S. aureus best antagonist. - less severe flares of AD had higher counts of S. epidermidis whereas the more severe flares were associated with S. aureus
  • [#Atopic Dermatitis] [#Staphylococcus lugdunensis] - #Staphylococcus hominis, S. lugdunensis and S. epidermidis produce several molecules capable of synergizing the innate antimicrobial response against S. aureus
  • [1.4] [#Atopic Dermatitis
    - samples where S. aureus was highly abundant, lower abundances of S. hominis and Cutibacterium acnes were observed. M. osloensis and M. luteus were more abundant in AD. - The flexures exhibited lower alpha-diversity and were colonized by S. aureus, accompanied by S. epidermidis in lesions. Malassezia species were absent on the neck in AD.
  • [1.5] [#Atopic Dermatitis
    - S. aureus, a dominant species among the family of Staphylococcae, can be 100 times more abundant in AD skin compared to normal healthy skin. - AD is associated with a depletion in the coagulase-negative staphylococcal species (CoNS), such as S. epidermidis, S. hominis, and other skin commensal bacterial communities, including Streptococcus salivarius, Propionibacterium, Streptococcus, Acinetobacter, Corynebacterium, Prevotella and Proteobacteria. - AD patients exhibit abundant S. aureus in their gut microbiota
  • [1.6] [#Natural Skin Microbiome
    - Other Staphylococcus spp. that inhabit the skin of humans, for example #Staphylococcus hominis and #Staphylococcus lugdunensis, may produce antimicrobial peptides that specifically inhibit colonization by S. aureus.
  • [1.7] [#Systemic lupus erythematosus
    - after Staphylococcus aureus was epicutaneously applied on NfkbizΔK5 mice, NfkbizΔK5 mice developed SLE-associated autoantibodies, anti-dsDNA antibodies, anti-Sm antibodies, and glomerulonephritis with IgG deposition. - This staphylococcal skin colonization promoted caspase-mediated keratinocyte apoptosis and neutrophil activation, inducing the interleukin-23 (IL-23)/IL-17 immune response by activating dendritic cells and T cells. - the subcutaneous administration of anti–IL-23p19 and anti–IL-17A antibodies alleviated the systemic autoimmune response.
  • [1.8
    - widespread class of #Bacillus lipopeptides, the fengycins, eliminates S. aureus by inhibiting S. aureus quorum sensing—a process through which bacteria respond to their population density by altering gene regulation. - consumption of #Probiotic #Bacillus bacteria comprehensively abolished colonization by the dangerous pathogen Staphylococcus aureus in a rural Thai population.
  • [1.9] [#Natural Skin Microbiome
    - upon injury, adaptive responses to the microbiota directly promote sensory neuron regeneration. - At homeostasis, tissue-resident commensal-specific T cells colocalize with sensory nerve fibers within the dermis, express a transcriptional program associated with neuronal interaction and repair, and promote axon growth and local nerve regeneration following injury.
  • - #Epigallocatechin gallate (ECGC) exert strong antimicrobial properties, binding to the Staphylococcus aureus peptidoglycan and destroying the osmotic protection of the cell wall.
  • [1.11
    - #Stearic acid, similar to #Palmitic acid, forms crystallite surfaces that display bactericidal activity against #Pseudomonas aeruginosa and Staphylococcus aureus.
  • [1.12] [#Atopic Dermatitis
  • [1.13] [#Bacillus subtilis
    - several microbiota species produce #Dopamine including #Bacillus cereus, B. subtilis and Staphylococcus aureus
  • [1.14] [#Cutaneous T cell lymphomas] [#Bacteriophage
    - #Endolysin strongly inhibits proliferation of S. aureus isolated from CTCL skin and significantly decreases S. aureus bacterial cell counts in a dose-dependent manner. - #Endolysin inhibits the patient-derived S. aureus induction of Interferon-gamma (IFNγ) and IFNγ-inducible chemokine CXCL10 in healthy skin. - #Endolysin strongly inhibits the effects of S. aureus on activation (reduced CD25 and STAT5 phosphorylation) and proliferation (reduced Ki67) of malignant T cells and cell lines in the presence of non-malignant T cells.
  • - Staphylococcus aureus (S. aureus) is suspected to fuel disease activity in cutaneous T cell lymphomas (CTCL).
  • [1.15] [#Atopic Dermatitis
    - Patients with AD exhibit decreased expression of #Antimicrobial peptides (AMPs) which is linked to increased colonization by Staphylococcus aureus.
  • [#Atopic Dermatitis] [#Ceramides] - The lesional skin of AD patients shows higher prevalence of S.aureus (up to 70%) than nonlesional skin of the same patients (39%) - The enzyme ceramidase secreted by S. aureus lowers lipid and fatty acid levels and makes the skin permeable to allergens. - Lower fatty acid levels also lead to decreased formation of phospholipid hydrolysis products in sebum and sweat, which increase skin surface pH and further promote S. aureus growth. - Alpha toxin secreted by S. aureus is cytotoxic to keratinocytes and alters the integrity of E-cadherin, compromising barrier function
  • [#Escherichia coli] - #RNAse7 showed higher inhibitory activity against E. Coli and #Cutibacterium acnes compared to S. aureus
  • - #Cutibacterium acnes secretes a lipase that converts triacylglycerols contained in sebum to #Propionic acid, which contributes to the acidification of the skin surface; a factor that limits the growth of S. aureus
  • [1.16] [#Natural Skin Microbiome] [#Staphylococcus epidermidis
    - tarIJLM (Staphylococcus aureus-type wall teichoic acid) alters the lifestyle of S. epidermidis from commensal to pathogenic
  • [1.17
    - #Firmicutes, such as #Clostridium botulinum, Clostridium tetani, #Clostridium perfringens, and Staphylococcus aureus, can produce proteinaceous toxins.
  • [1.18] [#Lactobacillus acidophilus, #Lactobacillus rhamnosus] [#Probiotic
    - L. rhamnosus did not affect the growth of TSS S. aureus but did inhibit the production of #Toxic shock syndrome toxin-1 (TSST-1) TSST-1; this effect was partially due to acidification of the growth medium. - L. acidophilus was both bactericidal and prevented the production of TSST-1 by S. aureus. This effect appeared to be partially due to acidification of the growth medium, production of H2O2, and production of other antibacterial molecules. - When both organisms were incubated with S. aureus, the effect of L. acidophilus LA-14 dominated.
  • [1.19] [#Enterococcus faecium
    - #Clovibactin efficiently kills drug-resistant Gram-positive bacterial pathogens without detectable resistance. - #Clovibactin exhibited antibacterial activity against a broad range of Gram-positive pathogens, including methicillin- resistant S. aureus (MRSA), daptomycin-resistant and #Vancomycin intermediate resistant S. aureus (VISA) strains, and difficult to treat #Vancomycin resistant #Enterococcus faecalis and E. faecium (#Vancomycin-resistant enterococci [VRE]).
  • - application of #Propionic acid on mice led to a significant decrease in the size of skin lesions infected with S. aureus USA300 and have direct antimicrobial activity against this pathogen.
  • [1.21] [#Skin wound
    - topical #Resveratrol treatment exhibited a significant antimicrobial efficacy against Staphylococcus aureus, #Pseudomonas aeruginosa, and #Candida albicans, which are discussed as significant pathogens in the context of non-healing wounds. - Resveratrols’ antimicrobial effects seemed to be even superior than some commercial antimicrobial (Levomecol) and antifungal (Clotrimazole) ointments.
  • [1.22] [#Antimicrobial peptides
    - #Staphylococcus epidermidis produces #Epidermin or the #Hominicin produced by #Staphylococcus hominis, with both AMPs being extremely effective against S. aureus
  • [#Staphylococcus hominis] [#Short peptide bacteriocins] - SPB from S. hominis which was capable of inhibiting S. aureus quorum sensing and limited S. aureus-mediated epidermal proteolysis and inflammatory response
  • [1.23] [#Antibiotic Therapy
    - #Indole is a bacterial signaling molecule that has been shown to influence bacterial movement, biofilm formation, antibiotic resistance, and the colonization of Staphylococcus aureus, #Salmonella enterica, and #Lactobacillus plantarum
  • [1.24] [#AA amyloidosis
    - prion-like proteins are conserved across multiple phyla and that at least 0.3% of all known bacteria genes encode for PrLDs. - pathogenic bacteria such as Staphylococcus aureus, #Enterococcus faecalis, #Enterococcus faecium, or #Staphylococcus epidermidis, this percentage could be higher and achieve 18%
  • [1.25] [#Staphylococcus epidermidis
    - The genus #Delftia, increased after #Balneotherapy, is instead known to degrade organic pollutants and includes both environmental and opportunistic pathogenic strains. - #Delftia was previously associated with a reduction of S. epidermidis and a consequent increase in S. aureus on the skin of patients with #Atopic Dermatitis
  • [1.26] [#Escherichia coli
    - #Lung cancer, suggested that E. coli and Staphylococcus aureus (S. aureus) may reside within these tumors
  • - S. aureus was suggested to be present in #Melanoma
  • [1.27] [#Cutaneous leishmaniasis] [#Leishmania braziliensis
    - Lesions enriched for Staphylococcus aureus expressed more inflammatory markers, especially IL-1β family members. - cutaneous IL-1β delayed lesion healing in mice colonized with S. aureus and infected with L. braziliensis.
  • [1.28
    - Staphylococcus aureus, a bacterial pathogen associated with itchy skin diseases, directly activates pruriceptor sensory neurons to drive itch. - Epicutaneous S. aureus exposure causes robust itch and scratch-induced damage. - S. aureus #Serine protease V8 as a critical mediator in evoking spontaneous itch and alloknesis. - V8 cleaves proteinase-activated receptor 1 (PAR1) on mouse and human sensory neurons.
  • [1.29] [#Escherichia coli
    - kimchi decreased E. coli significantly, while green #Cabbage had more effect against S.aureus
  • [#Escherichia coli] [#Lipopolysaccharide] - phenolic fractions of #Kale increased DPPH scavengers and decreased pathogenic bacteria, S. aureus and E. coli. - #Kale digesta rich in #Phenolic acids inhibited LPS and TNFÉ‘-induced intestinal epithelial cell inflammation and upregulated catalase, GSH, and #Superoxide dismutase antioxidant levels against cellular #Oxidative stress
  • [#Atopic Dermatitis] [#Roseomonas mucosa] - In 15 #Children with AD, R. mucosa treatment was associated with amelioration of disease severity, improvement in epithelial barrier function, reduced Staphylococcus aureus burden on the skin, and a reduction in topical steroid requirements without severe adverse events. - Skin improvements and colonization by R. mucosa persisted for up to 8 months after cessation of treatment.

References Notes

[  ]

Common References

MetaBiom only uses strictly necessary session cookies to give you the best possible experience on the website. By selecting "Accept essential cookies" you agree to the use of these cookies.