Endolysin {90000465}
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| Definition: | Endolysin |
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Shared Reference Notes
- [1.1] [#Cutaneous T cell lymphomas] [#Staphylococcus aureus] [#Bacteriophage]
- endolysin strongly inhibits proliferation of S. aureus isolated from CTCL skin and significantly decreases S. aureus bacterial cell counts in a dose-dependent manner. - endolysin inhibits the patient-derived S. aureus induction of Interferon-gamma (IFNγ) and IFNγ-inducible chemokine CXCL10 in healthy skin. - endolysin strongly inhibits the effects of S. aureus on activation (reduced CD25 and STAT5 phosphorylation) and proliferation (reduced Ki67) of malignant T cells and cell lines in the presence of non-malignant T cells.
References Notes
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