Veillonella ⇒ Cutibacterium acnes {10000230}
Parent: | |
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Definition: | Cutibacterium acnes |
Initialisation date: | 2020-06-01 |
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Rank: | Species |
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Domain: | Bacteria |
Enzyme: | α-amylases (α 1→6) |
Function: | [ ] |
Notes:
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Shared Reference Notes
- [1.1] [#Staphylococcus epidermidis]
- #Acne > increased #Actinobacteria followed by #Firmicutes and #Proteobacteria, #Cutibacterium,#Staphylococcus and #Corynebacterium. - C. acnes > major species in terms of mean abundance, followed by #Staphylococcus epidermidis (S. epidermidis) and #Staphylococcus hominis (S. hominis); - [1.2] [#Acne]
- An acneic Cutibacterium acnes strain as well as its porphyrins activate NRLP3 inflammasome assembly, while this was not observed with a non-acneic strain. - [1.3] [#Atopic Dermatitis]
- AD subjects is characterized by reduced microbial richness, depletion of Cutibacterium acnes, #Dermacoccus and #Methylobacterium species. - [1.4] [#Skin anatomy]
- C. acnes lineages coexist across an individual’s skin but not within the same pore - [1.5]
- Cutibacterium acnes (formerly, #Propionibacterium acnes) is a skin-associated commensal that has been detected in the prostate of men with #Prostate cancer in several studies. - C. acnes can induce cell proliferation and the secretion of cytokines and chemokines such as IL-6 and IL-8 - [1.6] [#Propionic acid] [#Ultraviolet Exposure]
- [1.7]
- #Lauric acid was shown to exert antimicrobial activity against Cutibacterium acnes - [1.8] [#Antibiotic Therapy]
- a strain of #Staphylococcus capitis (S. capitis E12) that selectively inhibited growth of C. acnes with potency greater than antibiotics commonly used in the treatment of #Acne. - [1.9]
- #Cutibacterium acnes secretes a thiopeptide RiPP called #Cutimycin that inhibits members of #Staphylococcus but does not affect the members of the genera #Corynebacterium and #Cutibacterium. - [#Escherichia coli, #Staphylococcus aureus] - #RNAse7 showed higher inhibitory activity against E. Coli and Cutibacterium acnes compared to S. aureus
- [#Staphylococcus aureus] - Cutibacterium acnes secretes a lipase that converts triacylglycerols contained in sebum to #Propionic acid, which contributes to the acidification of the skin surface; a factor that limits the growth of S. aureus
- [#Natural Skin Microbiome] - Cutibacterium acnes associated with healthy skin were shown to activate the release of extracellular traps from specialized Th17 subsets
- - More than 4% of people whose blood came back positive for a bacterial DNA, it was for a dominant skin microbiota, i.e. Cutibacterium acnes.
References Notes
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