Natural Med. Cond. ⇒ Skin aging {40000638}
Type: | Natural Med. Cond. |
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Parent: | [ ] |
Definition: | Skin aging |
Initialisation date: | [ ] |
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Other Terms: | [ ] |
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MedDra Level: | [ ] |
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Shared Reference Notes
- [1.1] [#UV radiation]
- Chronic UV exposure induces #Reactive Oxygen Species (ROS) production, activating three major skin #Aging cascades. - Resveratrol > prevent photo-#Aging through anti-inflammatory, antioxidant, and antitumour pathways. - The viability of cultured human keratinocytes (HaCaT cell line) pretreated with different doses of resveratrol significantly increased up to 94%. - - night-time topical antioxidant containing #Resveratrol, baicalin, and #Vitamin E for 12 weeks. - significant increase in collagen type II alpha 1 gene expression. - Supported with a clinical improvement in elasticity and skin thickness as measured by ultrasound.
- [#UV radiation] - In mice > oral or topical administration of #Resveratrol resulted in a suppression of UVB-induced epidermal thickening.
- [1.2] [#Corynebacterium kroppenstedtii]
- Cor. kroppenstedtii was likely responsible for the observed #Aging-related increase in #Corynebacterium. - [#Cutibacterium acnes] - C. acnes clade C is functionally related to skin aging.
- [#Cutibacterium acnes] - C. acnes was likely responsible for the #Aging-related depletion of #Cutibacterium
- - #Glyoxylate bypass pathwayup-regulation is observed during #Oxidative stress – a characteristic of skin aging.
- [#Streptococcus infantis, #Streptococcus pneumoniae] [#Aging] - younger Korean women carried a higher amount of skin #Streptococcus compared to older Korean women. - These #Streptococcus species, specifically #Streptococcus (St.) pneumoniae and St. infantis, can secrete substances that up-regulate #Collagen synthesis.
References Notes
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