Disease
Microbiota ☳
Metabolome
Factor
Corynebacteriaceae ⇒ Corynebacterium {10000263}
Record Keys
Parent:
Definition: Corynebacterium
Details
Initialisation date: 2020-10-02
Meta Information
Rank:
Domain:
Enzyme: [ ]
Function: Androgen-utilizing
Notes:
[ ] Shared Reference Notes
[1.1 ] [#Cutibacterium acnes , #Staphylococcus epidermidis ] - #Acne > increased #Actinobacteria followed by #Firmicutes and #Proteobacteria , #Cutibacterium ,#Staphylococcus and Corynebacterium .
- C. acnes > major species in terms of mean abundance, followed by #Staphylococcus epidermidis (S. epidermidis) and #Staphylococcus hominis (S. hominis);
[1.2 ] [#Atopic Dermatitis ] [#Staphylococcus aureus , #Staphylococcus epidermidis ] - increased abundance of S. aureus with depletion of S. epidermidis and Corynebacterium spp. among AD patients.
- S. epidermidis, a commensal present on non–inflamed skin, appears to be S. aureus best antagonist.
- less severe flares of AD had higher counts of S. epidermidis whereas the more severe flares were associated with S. aureus
[1.3 ] [#Covid-19 ] - SARS-CoV-2-infected participants with Corynebacterium /#Dolosigranulum -dominant microbiome profiles were less likely to have respiratory symptoms than infected participants with other nasopharyngeal microbiome profiles
[1.4 ] [#Parkinson’s Disease ] - Certain bacterial species of the genus Corynebacterium , #Porphyromonas , and #Prevotella have been noted to be significantly abundant in PD and associated with #SCNA genes .
- An overabundance of the unusually low Corynebacterium and endotoxins of the #Porphyromonas and #Prevotella can trigger the PD pathology in the gut.
[1.5 ] - The most abundantly cultivated bacterial organisms in a normal healthy eye are coagulase-negative #Staphylococci , #Acinetobacter , #Methylobacterium , #Propionibacterium , #Pseudomonas , #Streptophyta , #Sphingomonas , and Corynebacterium species
[1.6 ] - babies who are delivered by #Cesarean section (C-section) are often colonized by bacteria that are more commonly found on the skin, including #Staphylococcus , #Propionibacterium or Corynebacterium
[#Natural ear microbiota ] - The microbiota of the ear canal is similar to that found on the skin. Therefore, Corynebacterium , #Staphylococcus , and #Propionibacterium genera are prevalent taxa.
- middle ear is actually colonized by Proteobacteria, #Actinobacteria , and #Firmicutes
[1.7 ] -The antibacterial and antitumor defensin (HBD1) showed decreased levels in #Prostate cancer patients, while others (HBD2 and 3) were considerably increased.
- Abundance of #Staphylococcus , Corynebacterium and #Oxyphotobacteria genera was significantly higher, the abundance of #Faecalibacterium and #Bacteroides genera were significantly lower in prostate tumor samples compared to non-tumor samples.
- #Bacteroides , Parabacteroides and #Faecalibacterium abundance gradually decreased with the combined increase in HBD2 and HBD3.
- Higher Corynebacterium and #Staphylococcus abundances were measured together with higher HBD2 and HBD3 urinary levels.
[1.8 ] [#Natural Skin Microbiome ] - the moist sites of skin are primarily colonized by members of the genera #Staphylococcus and Corynebacterium .
[1.9 ] - #Kocuria and #Cutibacterium were enriched in healthy subjects, while #Staphylococcus was enriched in psoriatic disease.
- The relative abundance of Corynebacterium was higher in NL #Psoriatic Arthritis (PsA). samples compared with NL #Psoriasis (PsO) samples.
[#Ovarian cancer ] - distinct OC microbiome with general enrichment of several microbial taxa, including #Dialister , Corynebacterium , Prevotella, and #Peptoniphilus in the OC cohort in all body sites excluding stool and omentum particularly in OC patients with adverse treatment outcomes compared to those without events.
[1.11 ] - in the patients with #Non-Atopic Dermatitis , an abundance of #Bacillus and #Brevibacillus was significantly increased while that of Corynebacterium was significantly decreased in affected vs. unaffected skin
[1.12 ] [#Breast cancer ] - #Enterobacter , #Bacteroides , and #Bifidobacterium were more abundant in patients with BC.
- #Pseudomonas , #Staphylococcus , #Acinetobacter , and Corynebacterium 1 were more abundant in healthy controls.
- Corynebacterium 1 was increased after #Bellflower root intervention by 3.1-fold.
[1.13 ] [#Natural Skin Microbiome ] - #Aging > significant increase in Corynebacterium on the cheeks and forehead and #Acinetobacter on the scalp in the older group.
[#Natural Skin Microbiome ] [#Aging ] - At the genus level, old-aged skin exhibited an increase in Corynebacterium and a decrease in #Cutibacterium relative abundance
[1.14 ] [#Cutibacterium acnes ] - #Cutibacterium acnes secretes a thiopeptide RiPP called #Cutimycin that inhibits members of #Staphylococcus but does not affect the members of the genera Corynebacterium and #Cutibacterium .
-RiPPs from #Lactobacilli have shown to inhibit members of #Staphylococci , #Cutibacterium and Corynebacterium
[1.15 ] - The #Actinobacteria phylum includes pathogens (species of Corynebacterium , #Mycobacterium , #Nocardia , and #Propionibacterium ), #Soil inhabitants (Micromonospora and #Streptomyces species), plant commensals (Frankia spp.), and GI commensals (#Bifidobacterium spp.)
[1.16 ] [#Autoimmune disease ] - The genus Corynebacterium is a taxon of coryneform gram-positive bacilli or coccobacilli that colonize the mucous membranes and skin in humans.
- Corynebacterium is usually regarded as a clinically non-significant contaminant in cultures28, but is sometimes reported in the context of autoimmune diseases.
- Corynebacterium in the nasopharyngeal microbiome and peripheral blood leukocytes relates to #Kawasaki disease .
- #Staphylococcus and #Streptococcus species, Corynebacterium species may serve as novel pathogenic candidate microbes for #Vasculitis .
- Corynebacterium 1 in the gut was associated with disease duration, and serum IL-1β levels in patients with #Vitiligo
[1.17 ] [#Skin aging ] [#Corynebacterium kroppenstedtii ] - Cor. kroppenstedtii was likely responsible for the observed #Aging -related increase in Corynebacterium .
Intervention in Disease [ ]↥ by Factor
‐ Sleep Oral cavity Human [1.83 ]
Author: MetaBiom
Identifier: 10000263
URL: https://www.metabiom.org/microbiota/158/corynebacterium
Keywords: Microbiome, Dysbiosis, Microbiota, Organism, Bacteria
Common References
[1.1 ] Rhodomyrtus tomentosa Fruit Extract and Skin Microbiota: A Focus on C. acnes Phylotypes in Acne Subjects [2020] [Research] [Cosmetics] [Journal] [80001444 ]
[1.2 ] The Human Skin Microbiome in Selected Cutaneous Diseases [2022] [Review] [Frontiers in Cellular and Infection Microbiology] [Journal] [80002353 ]
[1.3 ] Age-related changes in the nasopharyngeal microbiome are associated with SARS-CoV-2 infection and symptoms among children, adolescents, and young adults [2022] [Study] [Clinical Infectious Diseases] [Journal] [80002363 ]
[1.4 ] Exploring the multifactorial aspects of Gut Microbiome in Parkinson’s Disease [2022] [Review] [Folia Microbiologica] [Journal] [80002403 ]
[1.5 ] Do Oral Pathogens Inhabit the Eye and Play a Role in Ocular Diseases? [2022] [Review] [Journal of Clinical Medicine] [Journal] [80002444 ]
[1.6 ] A complete guide to human microbiomes: Body niches, transmission, development, dysbiosis, and restoration [2022] [Review] [Frontiers in Systems Biology] [Journal] [80002487 ]
[1.7 ] Bladder Tissue Microbiome Composition in Patients of Bladder Cancer or Benign Prostatic Hyperplasia and Related Human Beta Defensin Levels [2022] [Study] [biomedicines] [Journal] [80002488 ]
[1.8 ] Characteristics of the Skin Microbiome in Selected Dermatological Conditions: A Narrative Review [2022] [Review] [Life] [Journal] [80002602 ]
[1.9 ] Alterations in the cutaneous microbiome of patients with psoriasis and psoriatic arthritis reveal similarities between non-lesional and lesional skin [2022] [Study] [Annals of the Rheumatic Diseases] [Journal] [80002680 ]
[1.10 ] Diagnostic and prognostic potential of the microbiome in ovarian cancer treatment response [2023] [Cohort study] [Scientific Reports] [Journal] [80002710 ]
[1.11 ] Cutaneous dysbiosis may amplify barrier dysfunction in patients with atopic dermatitis [2022] [Study] [Frontiers in Microbiology] [Journal] [80002724 ]
[1.12 ] Prediction of breast cancer using blood microbiome and identification of foods for breast cancer prevention [2023] [Study] [Scientific Reports] [Journal] [80002835 ]
[1.13 ] How Microbiomes Affect Skin Aging: The Updated Evidence and Current Perspectives [2022] [Review] [Life] [Journal] [80002854 ]
[1.14 ] Microbial derived antimicrobial peptides as potential therapeutics in atopic dermatitis [2023] [Review] [Frontiers in Immunology] [Journal] [80002951 ]
[1.15 ] Gut Microbiome–Brain Alliance: A Landscape View into Mental and Gastrointestinal Health and Disorders [2023] [Review] [ACS Chemical Neuroscience] [Journal] [80003039 ]
[1.16 ] Alteration of microbial composition in the skin and blood in vasculitis [2023] [80003438 ]
[1.17 ] Skin microbiome attributes associate with biophysical skin aging [2023] [80003473 ]
[1.18 ] Drinking alcohol is associated with variation in the human oral microbiome in a large study of american adults [2018] [Microbiome] [Journal] [80000944 ]
[1.19 ] Quantitative metagenomics reveals unique gut microbiome biomarkers in ankylosing spondylitis. [2017] [Genome Biology] [Journal] [80000612 ]
[1.20 ] Temporal shifts in the skin microbiome associated with disease flares and treatment in children with atopic dermatitis [2012] [Genome Research] [Journal] [80000491 ]
[1.21 ] Alterations of oral microbiota distinguish children with autism spectrum disorders from healthy controls [2018] [Scientific Reports] [Journal] [80000691 ]
[1.22 ] New evidences on the altered gut microbiota in autism spectrum disorders [2017] [Microbiome] [Journal] [80000956 ]
[1.23 ] Comparative ocular microbial communities in humans with and without Blepharitis [2012] [Immunology and Microbiology] [Journal] [80000393 ]
[1.24 ] Breast tissue, oral and urinary microbiomes in breast cancer [2017] [Oncotarget] [Journal] [80000875 ]
[1.25 ] Evaluation of cutaneous, oral and intestinal microbiota in patients affected by pemphigus and bullous pemphigoid: a pilot study [2020] [Experimental and Molecular Pathology] [Journal] [80001251 ]
[1.26 ] Carious status and supragingival plaque microbiota in hemodialysis patients [2018] [PLOS ONE] [Journal] [80000880 ]
[1.27 ] Analysis of the airway microbiota of healthy individuals and patients with chronic obstructive pulmonary disease by T-RFLP and clone sequencing. [2013] [PLOS ONE] [Journal] [80000383 ]
[1.28 ] Commensal microflora in human conjuctiva; characteristics of microflora in the patients with chronic ocular graf-versus-host disease [2019] [The Ocular Surface] [Journal] [80001080 ]
[1.29 ] Gut microbiota composition and Clostridium difficile infection in hospitalized elderly individuals: a metagenomic study [2016] [Scientific Reports] [Journal] [80001033 ]
[1.30 ] The conjunctival microbiome in health and trachomatous disease: a case control study. [2014] [Genome Medicine] [Journal] [80000391 ]
[1.31 ] Quantitation and Composition of Cutaneous Microbiota in Diabetic and Nondiabetic Men [2013] [Journal of Infectious Diseases] [Journal] [80000458 ]
[1.32 ] Oral microbiome signatures in diabetes mellitus and periodontal disease [2020] [Journal of Dental Research] [Journal] [80001350 ]
[1.33 ] Dysbiosis of urinary microbiota is positively correlated with type 2 diabetes mellitus [2017] [Oncotarget] [Journal] [80000429 ]
[1.34 ] Molecular detection of microbial colonization in cervical mucus of women with and without endometriosis [2019] [American Journal of Reproductive Immunology] [Journal] [80001113 ]
[1.35 ] Inflammation-associated microbiota in pediatric eosinophilic esophagitis [2015] [Microbiome] [Journal] [80000547 ]
[1.36 ] Dental black plaque: metagenomic characterization and comparative analysis with white-plaque [2020] [Research] [Scientific Reports] [Journal] [80001477 ]
[1.37 ] Analysis of the microbiota of black stain in the primary dentition [2015] [PLOS ONE] [Journal] [80001289 ]
[1.38 ] Alterations of gastric mucosal microbiota across different stomach microhabitats in a cohort of 276 patients with gastric cancer [2019] [EBioMedicine] [Journal] [80000998 ]
[1.39 ] Dynamic Changes in the Nasal Microbiome Associated with Disease Activity in Patients with Granulomatosis with Polyangiitis [2021] [Research] [Arthritis & Reumatology] [Journal] [80001716 ]
[1.40 ] Loss of skin microbial diversity and alteration of bacterial metabolic function in Hidradenitis suppurativa [2019] [The Journal of Investigative Dermatology] [Journal] [80001249 ]
[1.41 ] Effects of HIV viremia on the gastrointestinal microbiome of young MSM [2019] [AIDS] [Journal] [80000959 ]
[1.42 ] Microbiota profile is different for early and invasive colorectal cancer and is consistent throughout the colon [2020] [Journal of Gastroenterology and Hepatology] [Journal] [80001383 ]
[1.43 ] Signatures of oral microbiome in HIV-infected individuals with oral Kaposi’s sarcoma and cell-associated KSHV DNA [2020] [PLOS Pathogens] [Journal] [80001284 ]
[1.44 ] Gut microbiome analysis in Neuromyelitis Optica reveals overabundance of Clostridium perfringens [2016] [Annals of Neurology] [Journal] [80000694 ]
[1.45 ] Comparative study of vulva and abdominal skin microbiota of healthy females with high and average BMI [2019] [BMC Microbiology] [Journal] [80000935 ]
[1.46 ] Tongue coating microbiome data distinguish patients with pancreatic head cancer from healthy controls [2019] [Journal of Oral Microbiology] [Journal] [80001042 ]
[1.47 ] Distinct gut microbiota profiles in patients with primary sclerosing cholangitis and ulcerative colitis [2017] [World journal of gastroenterology] [Journal] [80000752 ]
[1.48 ] Characterization of intestinal microbiota in ulcerative colitis patients with and without primary sclerosing cholangitis [2016] [Journal of Crohn's and Colitis] [Journal] [80000753 ]
[1.49 ] Profiling the salivary microbiome of the Qatari population [2020] [Journal of Translational Medicine] [Journal] [80001335 ]
[1.50 ] Alterations in the Genital Microbiota in Women With Spinal Cord Injury [2016] [Original Research] [Journal] [80000468 ]
[1.51 ] Disordered cutaneous microbiota in systemic lupus erythematosus [2020] [Journal of Autoimmunity] [Journal] [80001253 ]
[1.52 ] Bacteriome and mycobiome associations in oral tongue cancer [2017] [Oncotarget] [Journal] [80001010 ]
[1.53 ] Comparative analysis of the vaginal microbiome of pregnant women with either Trichomonas vaginalis of Chamydia trachomatis [2019] [PLOS ONE] [Journal] [80001283 ]
[1.54 ] Temporal changes in gut microbiota profile in children with acute lymphoblastic leukemia prior to commencement-, during-, and post-cessation of chemotherapy [2020] [BMC Cancer] [Journal] [80001331 ]
[1.55 ] Subgingival microbiota in health compared to periodontitis and the influence of smoking [2015] [Frontiers in Microbiology] [Journal] [80000406 ]
[1.56 ] The infant airway microbiome in health and disease impacts later asthma development [2015] [Cell Host Microbe] [Journal] [80000735 ]
[1.57 ] Different upper airway microbiome and their functional genes associated with asthma in young adults and elderly individuals [2019] [Allergy] [Journal] [80001003 ]
[1.58 ] Gut microbiota profile in children affected by atopic dermatitis and evaluation of intestinal persistence of a probiotic mixture [2019] [Scientific Reports] [Journal] [80000949 ]
[1.59 ] Gut microbiota features in young children with autism spectrum disorders [2018] [Frontiers in Microbiology] [Journal] [80000980 ]
[1.60 ] 16 S rDNA microbiome composition pattern analysis as a diagnostic biomarker for biliary tract cancer [2020] [World Journal of Surgical Oncology] [Journal] [80001333 ]
[1.61 ] The urinary microbiome associated with bladder cancer [2018] [Scientific Reports] [Journal] [80001102 ]
[1.62 ] The microbiota of breast tissue and its association with breast cancer [2016] [Applied and Environmental Microbiology] [Journal] [80000898 ]
[1.63 ] Molecular characterization of skin microbiota between cancer cachexia patients and healthy volunteer [2014] [Microbial Ecology] [Journal] [80001180 ]
[1.64 ] Relationship of children’s salivary microbiota with their caries status: a pyrosequencing study. [2014] [Clinical oral investigations] [Journal] [80000348 ]
[1.65 ] Blood microbiome profile in CKD: A pilot study [2019] [Clinical Journal of the American Society of Nephrology] [Journal] [80000967 ]
[1.66 ] Skin microbiome imbalance in patients with STAT1/STAT3 defects impairs innate host defense responses [2014] [Journal of Innate immunity] [Journal] [80001196 ]
[1.67 ] Metagenome and metatranscriptome profiling of moderate and severe COPD sputum in Taiwanese Han Males [2016] [PLOS ONE] [Journal] [80000876 ]
[1.68 ] Evidence of Microbiota Dysbiosis in Chronic Rhinosinusitis [2016] [International forum of allergy & rhinology] [Journal] [80000510 ]
[1.69 ] The difference in nasal bacterial microbiome diversity between chronic rhinosinusitis patients with polyps and a control population [2019] [International forum of allergy & rhinology] [Journal] [80000992 ]
[1.70 ] Comparison of oropharyngeal microbiota from children with asthma and cystic fibrosis [2017] [Mediators of Inflammation] [Journal] [80000734 ]
[1.71 ] Decreased diversity of the oral microbiota of patients with hepatitis B virus-induced chronic liver disease: a pilot project [2015] [Scientific Reports] [Journal] [80000571 ]
[1.72 ] Altered gut microbiota composition associated with eczema in infants [2016] [PLOS ONE] [Journal] [80000741 ]
[1.73 ] Distinct nasopharyngeal and oropharyngeal microbiota of children with influenza A virus compared with healthy children [2018] [BioMed Research International] [Journal] [80000961 ]
[1.74 ] Comparative analysis of the oral microbiota between iron-deficiency anaemia (IDA) patients and healthy individuals by high-throughput sequencing [2019] [BMC Oral Health] [Journal] [80001259 ]
[1.75 ] The microbiome of the nasolacrimal system and its role in nasolacrimal duct obstruction [2020] [Ophtalmic Plastic and Reconstructive Surgery] [Journal] [80001361 ]
[1.76 ] A microbiome case-control study of recurrent acute otitis media identified potentially protective bacterial genera [2018] [BMC Microbiology] [Journal] [80000688 ]
[1.77 ] Identification and characterization of blood and neutrophil-associated microbiomes in patients with severe acute pancreatitis using next-generation sequencing [2018] [Frontiers in Cellular and Infection Microbiology] [Journal] [80000703 ]
[1.78 ] Oral and nasal microbiota in Parkinson’s disease [2017] [Parkinsonism and Related Disorders] [Journal] [80000279 ]
[1.79 ] Periodontal disease and the oral microbiota in new-onset rheumatoid arthritis [2012] [Arthtitis & Rheumatism] [Journal] [80000389 ]
[1.80 ] Molecular characterization of circulating microbiome signatures in rheumatoid arthritis [2020] [Frontiers in Cellular and Infection Microbiology] [Journal] [80001275 ]
[1.81 ] Cigarette smoking and the oral microbiome in a large study of American adults [2016] [The ISME Journal] [Journal] [80000996 ]
[1.82 ] Microbial community profiling shows dysbiosis in the lesional skin of Vitiligo subjects_DUBLICATE [2016] [Scientific Reports] [Journal] [80000494 ]
[1.83 ] Impact of sleep on the microbiome of oral biofilms [2021] [Research] [PLOS ONE] [Journal] [80002158 ]