Disease ⇒ Iron-deficiency anaemia {40000466} Record Keys Type:Disease Parent:[ ] Definition:Iron-deficiency anaemia Details Initialisation date:[ ] Other Terms:IDA Meta Information MedDra ID:10022972 MedDra Level:pt ICD:[ ] Category:[ ] Zone:[ ] Mechanism:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Short Chain Fatty Acid] - In iron-deficient rats, significantly lower concentrations of faecal butyrate and propionate were retrieved and the bacterial composition was strongly modified, involving a higher abundance of Lactobacilli and Enterobacteriaceae and a significant decrease of Roseburia species and Eubacterium rectale, which are major butyrate producers. In the same study, repletion of iron by the administration of FeSO4 led to increased caecal butyrate concentrations and partially restored microbial populations. [1.2] [#Iron] - #Consumption of Fe supplements increases > Fe in the large intestine > reducing the amount of lactic acid bacteria (bifidobacteria and #Lactobacilli) and increasing the entropathogenic Escherichia coliReferences Notes[ ]
