Disease ⇒ Otitis Media {40000328}

Record Keys


Type:
Disease
Parent:[  ]
Definition:
Otitis Media

Details


Initialisation date:[  ]
Other Terms:[  ]

Meta Information


MedDra ID:
10033078
MedDra Level:
pt
ICD:[  ]
Category:[  ]
Zone:[  ]
Mechanism:[  ]

Notes:


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Shared Reference Notes


  • [1.1] [#Natural ear microbiota
    - #Streptococcus salivarius (S. salivarius), a bacterial species which populates the mouth and gut in early neonatal developmentand which is commonly found in the respiratory tract, may have a beneficial influence on the ear microbiome. - The K12 strain of S. salivarius has specifically been recognized as a potential #Probiotic for treating otitis media, due to the ability of this strain to target and suppress pathogenic bacteria in the ear.
  • [#Candida albicans] [#IL-1b, #TNF-alfa] - introducing C. albicans into the guts of mice, a greater degree of ear swelling occurred accompanied by higher levels of proinflammatory cytokines (IL-1β, #IL-6 and TNF-α) in the ear
  • [#Streptococcus salivarius] - The production of bacterial peptides known as ‘#Bacteriocins’, which can interfere with growth of other bacteria, makes bacterial strains such as #Lactobacillus salivarius PS7 and S. salivarius 24SMB particularly interesting with regard to their potential for treating middle ear infections
  • [#Urolithins] - An oral supply of #Urolithin A was shown to counteract myeloperoxidase activity and inflammation within the ear

References Notes


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