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Microbiome & Chronic Diseases

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Staphylococcus epidermidis ⇒ Staphylococcus {10000106}

Record Keys


Organism:
Staphylococcus epidermidis
Parent:

Details


Initialisation date:
2020-09-06

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Meta Information


Rank:
 Species
Domain:
 Bacteria
Enzyme:[  ]
Function:[  ]

Notes:


[  ]

References Notes


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Shared Reference Notes


  • [1.3] [#Cutibacterium acnes
    - #Acne > increased #Actinobacteria followed by #Firmicutes and #Proteobacteria, #Cutibacterium,#Staphylococcus and #Corynebacterium. - C. acnes > major species in terms of mean abundance, followed by #Staphylococcus epidermidis (S. epidermidis) and #Staphylococcus hominis (S. hominis);
  • [1.5] [#Atopic Dermatitis] [#Staphylococcus aureus
    - increased abundance of S. aureus with depletion of S. epidermidis and #Corynebacterium spp. among AD patients. - S. epidermidis, a commensal present on non–inflamed skin, appears to be S. aureus best antagonist. - less severe flares of AD had higher counts of S. epidermidis whereas the more severe flares were associated with S. aureus
  • [1.22] [#Phenol-soluble modulin (PSM)
    - S. epidermidis produces the peptides PSMγ and PSMδ, which inhibit the growth of pathogenic bacteria on the skin.
  • [1.23] [#Colitis] [#Breast feeding
    - S. epidermidis is predominantly a commensal skin microbe in humans but can also colonize the infant gut as a founding member in part through breastmilk seeding. - S. epidermidis tends to disappear from the gut with age, its presence during early immune education may facilitate establishment of a largely tolerogenic intestinal memory CD4+ T cell pool. - S. epidermidis can turn pathologic when it becomes bloodborne in an at-risk host.
  • [1.24] [#Short Chain Fatty Acid
    - Staphylococcus epidermidis, and molecular mechanisms are activated by SCFAs via the liver feedback mechanism
  • [1.25] [#Natural Skin Microbiome
    - Staphylococcus epidermidis, can also interact with the host’s keratinocytes directly, thereby inducing the production of antimicrobial peptides via immune cell signaling.

Common References