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Microbiome & Chronic Diseases

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Symptom ⇒ Dry Skin {40000579}

Record Keys


Type:
Disease, Symptom
Parent:[  ]
Definition:
Dry Skin

Details


Initialisation date:[  ]
Other Terms:[  ]

Meta Information


MedDra ID:[  ]
MedDra Level:[  ]
ICD:[  ]
Category:[  ]
Zone:
 Skin
Mechanism:[  ]

Notes:


[  ]

References Notes


[  ]

Shared Reference Notes


  • [1.1] [#Natural Skin Microbiome
    - abundant skin commensal #Staphylococcus epidermidis contributes to skin barrier integrity. - S. epidermidis secretes a sphingomyelinase that acquires essential nutrients for the bacteria and assists the host in producing #Ceramides, the main constituent of the epithelial barrier that averts skin dehydration and aging. - In mouse models, S. epidermidis significantly increases skin ceramide levels and prevents water loss of damaged skin in a fashion entirely dependent on its sphingomyelinase.