Symptom ⇒ Dry Skin {40000579} Record Keys Type:Disease, Symptom Parent:[ ] Definition:Dry Skin Details Initialisation date:[ ] Other Terms:[ ] Meta Information MedDra ID:[ ] MedDra Level:[ ] ICD:[ ] Category:[ ] Zone: Skin Mechanism:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Natural Skin Microbiome] - abundant skin commensal #Staphylococcus epidermidis contributes to skin barrier integrity. - S. epidermidis secretes a sphingomyelinase that acquires essential nutrients for the bacteria and assists the host in producing #Ceramides, the main constituent of the epithelial barrier that averts skin dehydration and aging. - In mouse models, S. epidermidis significantly increases skin ceramide levels and prevents water loss of damaged skin in a fashion entirely dependent on its sphingomyelinase. [1.2] [#Psoriasis] - #Brevibacterium was reported to be predominant in skin samples of psoriatic lesions, #Senile pruritis subjects and on skin of elderly bedridden subjects often presenting dry skin with possible localized infected woundsReferences Notes[ ]
