Sphingomonadaceae ⇒ Sphingomonas {10000820}

Shared Reference Notes

• [1.1] [#Parkinson’s Disease] 
  - #Aquabacterium, #Peptococcus, and Sphingomonas are associated with motor complications in PD
• [1.2] 
  - The most abundantly cultivated bacterial organisms in a normal healthy eye are coagulase-negative #Staphylococci, #Acinetobacter, #Methylobacterium, #Propionibacterium, #Pseudomonas, #Streptophyta, Sphingomonas, and #Corynebacterium species
• [1.3] 
  - Sphingomonas and #Erythrobacteraceae, may have the ability to protect against #UV radiation as they produce potentially protective compounds. Indeed, further analysis showed that a Sphingomonas spp. was able to reduce #Reactive Oxygen Species levels in human keratinocytes.
• [1.4] [#Crohn’s disease] [#Dorea longicatena, #Ruminococcus lactaris] 
  - ileocolonic resection (ICR) in CD patients > amples collected at time of surgery were enriched in #Proteobacteria and harbored high levels of unusual, bacteria such as #Streptococcus mitis, #Undibacterium oligocarboniphilum, Sphingomonas melonis and #Gemella haemolysans - 6 months after surgery samples had elevated proportions of anaerobic bacteria belonging to #Lachnospiraceae (#Clostridium nexile, #Blautia wexlereae, #Dorea longicatena). - Remission was characterized by increased levels of bacteria belonging to #Bacteroides, #Dorea, #Ruminococcus and #Dialister genera, whereas recurrence was associated with increased levels of #Gemmiger formicilis, #Enterococcus durans and #Ruminococcus lactaris.
• [1.5] 
  - Sphingomonas was more abundant in patients with eosinophil-high #Asthma than in those with eosinophil-low #Asthma.
• [#Eosinophilic chronic rhinosinusitis] - nasal dysbiosis in eCRSwNP was defined by increased relative abundances of Sphingomonas, #Moraxellaceae, #Bacteroides, #Bifidobacterium, #Ruminococcus, and #Faecalibacterium, as well as by decreased abundances of #Ralstonia, #Propionibacterium, and Propionibacter.
• [#Eosinophilic chronic rhinosinusitis] - Sphingomonas was more abundant in patients with eCRSwNP than in HCs. - Sphingomonas species have been associated with increased airway hyperresponsiveness to methacholine. - #Glycolipid antigens from Sphingomonas species are believed to induce airway hyperresponsiveness in mice through activation of invariant natural killer T cells in an IL-33–dependent manner. - Sphingomonas abundance was correlated with high absolute tissue eosinophil counts in patients with eCRSwNP.

References Notes