Microbiome & Chronic Diseases

Evidence Based Medicine
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Plant Microbiome {51111201}

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Plant Microbiome
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Diet, Environment
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Shared Reference Notes

  • [1.1
    - Cultivation-independent 16S rRNA gene V3/V3–V4 amplicon profiling on 40-year-old grape cell/callus tissues revealed a high bacterial diversity (>250 genera), predominantly Proteobacteria, succeeded by Firmicutes, Actinobacteria, Bacteriodetes, Planctomycetes, and 20 other phyla, including several candidate phyla.
  • [1.2] [#Plant-based diet
    - several putative short-chain fatty acid (SCFA) fermenters associated with eating more than 30 types of plants, including sOTUs putatively of the species Faecalibacterium prausnitzii and of the genus Oscillospira. - Because bacteria differ in their carbohydrate binding modules and enzymes that hydrolyze diverse substrates in the gut (28), a diet containing various types of dietary fibers and resistant starches likely supports a more diverse microbial community. - Individuals who consume more than 30 types of plants per week compared to those who consume 10 or fewer plants per week had significantly reduced abundance of antibiotic resistance genes for aminoglycosides, chloramphenicol, and major facilitator superfamily (MFS) transporters (antibiotic efflux pumps).
  • [1.3] [#Molecular patterns
    - Antigenic microbial debris as MAMPs in certain botanical supplements are immune stimulants, liken to vaccines adjuvants. - large number of plants to discern > high concentration of bio-active MAMPS. - 65 out of 2000+ tested with high TLR4 agonist MAMP presence and investigate the plant vs. the microbiome.
  • [1.4] [#High fibre plant protein-rich diet, #Plant-based diet
    - #Prevotella thrives on plant- or fiber-rich diets. - These include diets commonly described as non-Western, Mediterranean, or rural African diet.

References Notes

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