Lachnospiraceae ⇒ Coprococcus {10000174} Record Keys Parent:Lachnospiraceae Definition:Coprococcus Details Initialisation date:2020-09-06 LinksSource Meta Information Rank: Genus Domain: Bacteria Zone:[ ] Enzyme:[ ] Function:Anti fibrosis Notes: [ ]Shared Reference Notes [1.1] - #Protein powder consumption > decrease in #Lachnospiraceae, #Roseburia, #Blautia, Synergistales, Coprococcus, #Lactobacillales, Bacilli, #Bifidobacterium longum and #Firmicutes. - #Protein powder consumption > higher abundance of #Bacteroidetes. [1.2] - Members of the genera #Oscillospira and Coprococcus in the cecum, as well as #Faecalibacterium prausnitzii and members of the genus #Bacteroides in the ileum > negatively correlated with #Fibrosis. [1.3] [#Diabetes Type 2] [#Coprococcus etes] - There are 36 different strains of #Butyrate-producing bacteria, and five of them are associated with increased insulin sensitivity: Coprococcus etes, #Oscillibacter sp. CAG 241, #Alistipes finegoldi and #Faecalibacterium prausnitzii. - The genus Coprococcus was associated with higher insulin sensitivity and disposition index and a lower rate of dysglycemia. [1.4] [#Crohn’s disease] [#Clostridium cluster IV] - #Roseburia, #Gemmiger, Coprococcus, #Ruminococcus 2, #Butyricicoccus, #Dorea, #Fusicatenibacter, #Anaerostipes, Clostridium IV were enriched in the healthy controls. - #Blautia, Clostridium IV, Coprococcus, #Dorea, #Fusicatenibacter continued to significantly decrease in early and advanced CD patients, and Escherichia/Shigella and Proteus continued to significantly increase. - negative correlation between #Dorea, #Butyricicoccus, #Roseburia and gland reduce, #Roseburia and FC, #Butyricicoccus and goblet cells decreased, Parabacterodies and sex, Clostridium IV and CRP, #Dorea and ESR . - positive correlation between Escherichia/Shigella and CRP, #Ruminococcus 2 and clinical symptoms. [1.5] [#Diabetes Type 2] - A reduction in the #Lachnospira, #Roseburia, #Faecalibacterium and Coprococcus genera in the T2D group. - These genera were #Butyrate producers. - The decrease of these genera favored #Obesity and the development of diseases. [1.6] - #Subdoligranulum and Coprococcus were consistently found to be depleted in individuals with generalized #Anxiety disorder and #Depression - Both #Subdoligranulum and Coprococcus are involved in the production of #Butyrate [1.7] [#Bipolar disorder, #Major depressive disorder, #Schizophrenia] - Gut microbiota in BD, MDD and SZ > increase in #Eggerthella and #Lactobacillus, together with a decrease in Coprococcus was common for the three conditions in comparison to controls. [1.8] [#Natural Small intestine Microbiome] [#Proton pump inhibitors] - PPI > induce SI duodenal microbiota dysbiosis, characterized by an increase in #Akkermansia muciniphila and #Porphyromonas endodontalis and a decrease in #Enterococcaceae, Coprococcus, #Enterobacteriaceae, and #Synergistes species [1.9] [#Behcet’s Disease] - Depleted #Dorea, #Blautia, Coprococcus, #Erysipelotrichaceae and #Lachnospiraceae as well as enriched #Bilophila and #Stenotrophomonas were identified in BU patients. [#Obesity] [#Collinsella aerofaciens] - subjects with BMI values ≥25 kg/m2 have higher relative abundances of members of the #Collinsella genus (e.g., #Collinsella aerofaciens), and the #Veillonellaceae and #Lachnospiraceae families (e.g., genera #Dorea, #Lachnospira, Coprococcus). [#Obesity] - Coprococcus abundance correlates positively with level of subcutaneous body fat. [#Obesity] - Coprococcus genus and #Lachnospiraceae, were more abundant in subjects with BMI ≥25 kg/m2 and those with greater skeletal muscle mass [1.11] - In patients with #Psoriatic Arthritis, there was a decrease in the abundance of certain bacteria such as #Akkermansia, #Ruminococcus, #Pseudobotyrivibrio, #Paraacteroides, #Alistipes, and Coprococcus [1.12] [#Omega 3] - omega-3 rich diet has been shown to result in a significant increase in #Subdoligranulum, along with other #Butyrate producers like #Anaerostipes, Coprococcus, and #Roseburia. [#Juvenile idiopathic arthritis] - ABIS JIA had higher abundance of #Acidaminococcales, #Prevotella 9, and #Veillonella parvula and lower abundance of Coprococcus, #Subdoligranulum, #Phascolarctobacterium, #Dialister spp., #Bifidobacterium breve, #Fusicatenibacter saccharivorans, #Roseburia intestinalis, and #Akkermansia muciniphila [1.13] [#Fasting] - RIF was associated with significant drops in the levels of seven genera at the end of Ramadan: #Blautia, Coprococcus, #Dorea, #Faecalicatena, #Fusicatenibacter, #Lachnoclostridium, and #Mediterraneibacter. [#Fasting] - Coprococcus produce #Butyrate. - genera Coprococcus significantly decreased after RIF. - Coprococcus experienced a decrease during starvation, but later on, they increased during the refeeding [#Keto diet] - Coprococcus abundance was decreased in subjects who were fed a ketogenic diet [#Meat-based diet] - a strict #Vegan diet led to an increase in Coprococcus levels, while a meat-rich diet (>150 g of meat per day) resulted in a decrease [#Obesity] - individuals with an overweight phenotype have increased levels of specific bacterial genera in the #Firmicutes phylum, including #Blautia, Coprococcus, and #Dorea [1.14] - Coprococcus has consistently demonstrated a low abundance in intestinal, neuropsychological, and neurodegenerative disorders [#Omega 3, #β-Galacto-oligosaccharides] [#High fibre diet] - Coprococcus abundance can be rapidly increased by fibre, galacto-oligosaccharides, or omega-3 fats supplementation, as well as by #Probiotic administration - #Depression > depletion of Coprococcus [#Parkinson’s Disease] [#Coprococcus catus, #Coprococcus comes] - all Coprococcus members produce #Butyrate or via independent mechanisms, such as the potential of C. catus and C. comes to synthesise #DOPAC, a metabolite implicated in PD. [#Parkinson’s Disease] [#Coprococcus eutactus] - specific correlations between C. eutactus and PD and between C. eutactus and language development were found, whereas most studies reported associations between the Coprococcus genus. [1.15] - Reduced abundance of the genus Coprococcus in #Alzheimer’s disease, which is associated with #Amyloid accumulation. [1.16] [#Bacteroides-Prevotella group, #Ruminococcus gauvreauii] - marked reduction in #Butyrate-producing bacterial genera, such as Coprococcus, and #Subdoligranulum, in both the ileum and colon; #Faecalibacterium in colon; and [#Ruminococcus] gauvreauii group in fecal samples from People living with HIV (PLWH) - #Erysipelotrichaceae UCG-003, Coprococcus, #Faecalibacterium, and #Subdoligranulum, significantly lower in PLWH and were associated with slower rates of biological #Aging. [1.17] [#Gout] - Altered compositions of microbiota, characterized by a reduced abundance of genus Coprococcus, were found in subjects with #Hyperuricemia compared with those with normouricemia. [1.18] - Researchers identified two bacterial genera Coprococcus and #Dialister were depleted in patients with #Depression whether or not they were taking antidepressants. References Notes[ ]