Ruminococcaceae ⇒ Subdoligranulum {10000138}

Shared Reference Notes

• [1.1] [#Psychogenic erectile dysfunction] 
  - Erectile dysfunction > no #Alloprevotella . - Erectile dysfunction > increased #Streptococci and Subdoligranulum - Erectile dysfunction > decreased #Prevotella sp.9, #Blautia, #Lachnospiraceae NK4A136 groups and #Roseburia.
• [1.2] [#Rheumatoid Arthritis] 
  -IgG and IgA autoantibodies from individuals who are at risk for RA cross-react against gut bacteria in the #Lachnospiraceae and #Ruminococcaceae families. - Analysis identified a bacterial strain from the Subdoligranulum genus that was associated with autoantibody development. - Mice colonized with this Subdoligranulum isolate developed arthritis with pathology similar to human RA.
• [1.3] [#Diabetes Type 2] 
  - The reduction of Subdoligranulum can also be assumed to have a negative impact and is thus characteristic of type 2 diabetes mellitus disease.
• [1.4] 
  - Subdoligranulum and #Coprococcus were consistently found to be depleted in individuals with generalized #Anxiety disorder and #Depression
• - Both Subdoligranulum and #Coprococcus are involved in the production of #Butyrate
• [#Depression] [#Christensenellaceae, #Coprococcus eutactus, #Lachnospiraceae] - RuminococcaceaeUCG005 as the most important genus in predicting depressive symptoms. - #Sellimonas, #Eggerthella, #Lachnoclostridium and #Hungatella were more abundant in individuals with higher depressive symptoms. - 12 genera and 1 microbial family associated with depressive symptoms > genera #Sellimonas, #Eggerthella, #Ruminococcaceae (UCG002, UCG003, UCG005), #Lachnoclostridium, #Hungatella, Coprococcus, LachnospiraceaeUCG001, Ruminococcusgauvreauiigroup, #Eubacterium ventriosum, Subdoligranulum and family #Ruminococcaceae.
• [#Omega 3 Supplementation] - Subdoligranulum was found to be increased in #Omega 3 rich diet.
• [1.5] [#Mild Cognitive Impairment] 
  - the abundance of #Butyrate producing bacteria such as #Lachnospiraceae family, Subdoligranulum sp., #Roseburia intestinalis, and #Roseburia hominis were reduced in the gut of MCI participants compared to cognitively healthy controls.

References Notes