Microbiome & Chronic Diseases

Evidence Based Medicine

Fri 24 March 2023 Sign in

Disease ⇒ Colon adenomas {40000235}

Record Keys
Type:	Disease
Parent:	[ ]
Definition:	Colon adenomas

Details
Initialisation date:	[ ]
Other Terms:	[ ]

Meta Information
MedDra ID:	10048832
MedDra Level:	pt
ICD:	[ ]
Category:	[ ]
Zone:	[ ]
Mechanism:	[ ]

Notes:

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Shared Reference Notes

[1.1] [#Colorectal cancer] [#Deoxycholic acid, #Secondary bile acids, #Ursodeoxycholic acid]
- UDCA has microbiome-changing and DCA‐lowering prpperties. - treatment with UDCA, decreased recurrence of adenomas with high-grade dysplasia. - DCA also stimulates the uptake of polyamines in CRC cells, which also have tumorigenic effects.

References Notes

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↥ Microbiota

‐ Atopobium Colonoscopy aspirate Human [1.2]
‐ Bacteroidetes Tissue biopsie Human [1.3]
‐ Chloroflexi Tissue biopsie Human [1.3]
‐ Dorea Tissue biopsie Human [1.4]
‐ Erysipelotrichaceae Colonoscopy aspirate Human [1.2]
‐ Faecalibacterium Tissue biopsie Human [1.4]
‐ Fusobacterium varium Colonoscopy aspirate Human [1.2]
‐ Fusobacterium Colonoscopy aspirate Human [1.2]
‐ Fusobacterium Tissue biopsie Human [1.5]
‐ Lactococcus Tissue biopsie Human [1.3]
‐ Megamonas Colonoscopy aspirate Human [1.2]
‐ Parvimonas Colonoscopy aspirate Human [1.2]
‐ Proteobacteria Tissue biopsie Human [1.3]
‐ Pseudomonas Tissue biopsie Human [1.3]
‐ Ruminococcus Tissue biopsie Human [1.4]
‐ Shigella Tissue biopsie Human [1.4]
‐ Subdoligranulum Stool Human [1.6]
‐ Tenericutes Tissue biopsie Human [1.3]
‐ Veillonella Colonoscopy aspirate Human [1.2]

↧ Microbiota

‐ Bacteroides Tissue biopsie Human [1.4]
‐ Butyricicoccus Colonoscopy aspirate Human [1.2]
‐ Butyricimonas Colonoscopy aspirate Human [1.2]
‐ Collinsella Colonoscopy aspirate Human [1.2]
‐ Comamonas Colonoscopy aspirate Human [1.2]
‐ Coprococcus Tissue biopsie Human [1.4]
‐ Firmicutes Tissue biopsie Human [1.3]
‐ Fusobacterium nucleatum Colonoscopy aspirate Human [1.2]
‐ Fusobacterium periodonticum Colonoscopy aspirate Human [1.2]
‐ Lachnobacterium Colonoscopy aspirate Human [1.2]
‐ Lachnoclostridium Stool Human [1.6]
‐ Mitsuokella Colonoscopy aspirate Human [1.2]
‐ Moraxellaceae Colonoscopy aspirate Human [1.2]
‐ Oscillibacter Stool Human [1.6]
‐ Salmonella Colonoscopy aspirate Human [1.2]
‐ Synergistaceae Colonoscopy aspirate Human [1.2]

Intervention by Microbiota

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↥ Metabolome

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↧ Metabolome

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Intervention by Metabolome

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Related Factor

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Subclass

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References

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Author: MetaBiom
Identifier: 40000235
URL: https://www.metabiom.org/disease/135/colon-adenomas
Keywords: Microbiome, Dysbiosis, Chronic

Common References

[1.1] Microbial Metabolite Dysbiosis and Colorectal Cancer [2023] [Review] [Gut and Liver] [Journal] [80002741]
[1.2] Metagenomic analyses of the gut microbiota associated with colorectal adenoma [2019] [PLOS ONE] [Journal] [80001024]
[1.3] Mucosal adherent bacterial dysbiosis in patients with colorectal adenomas [2016] [Scientific Reports] [Journal] [80000407]
[1.4] Molecular characterization of mucosal adherent bacteria and associations with colorectal adenomas [2010] [Gut microbes] [Journal] [80000590]
[1.5] Fusobacterium is associated with colorectal adenomas [2013] [PLOS ONE] [Journal] [80000575]
[1.6] Stool microbiota composition in patients with stomach, colon, and rectal neoplasms [2018] [Digestive Diseases and Sciences] [Journal] [80000819]