Disease ⇒ Dry eye syndrom {40000166}

Record Keys

Parent:[  ]
Dry eye syndrom


Initialisation date:
Other Terms:
Keratoconjunctivitis sicca , DES


Meta Information

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Shared Reference Notes

  • [1.1
    - Proteobacteria, Firmicutes/Bacteroidetes ratio, and genus Lactobacillus, Alistipes, Prevotella, Paraprevotella, and Helicobacter to be significantly associated with dry eye severity.
  • [1.2
    - Microbial communities in dry eye disease are distinct and remain distinct even with daily saline eye wash. - In dry eye disease, increased microbial diversity is a hallmark of disease.
  • [1.3] [#Short Chain Fatty Acid
    - Dry eye syndrom > Reduced SCFA has been found to alter the circadian rhythm, which in turn reduces lacrimal gland secretions.
  • [1.4
    - family #Propionibacteriaceae and the species #Corynebacterium tuberculostearicum were more abundant in DED patients compared to controls. - Both #Corynebacterium tuberculostearicum and bacteria of the family #Propionibacteriaceae are involved in inflammatory processes through the upregulation of pro-inflammatory cytokines that may be associated with DED.
  • - the conjunctiva of DED patients was decreased in genes of L-lysine biosynthesis, tetrapyrrole biosynthesis, 5-aminoimidazole ribonucleotide biosynthesis, and the super pathway of L-#Threonine biosynthesis.
  • [1.5
    - #Streptococcus and #Pedobacter bacteria species were the most prevalent microbes in healthy eyes while more #Acinetobacter species were present in the eye microbiomes of people with dry eye.

References Notes

  • [1.8
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