Disease ⇒ Dry eye syndrom {40000166}

Record Keys


Type:
Disease
Parent:[  ]
Definition:
Dry eye syndrom

Details


Initialisation date:
2019-06-23
Other Terms:
Keratoconjunctivitis sicca , DES

Links


Meta Information


MedDra ID:
10013774
MedDra Level:
pt
ICD:[  ]
Category:
Ophtalmology
Zone:[  ]
Mechanism:[  ]

Notes:


[  ]

Shared Reference Notes


  • [1.1
    - Proteobacteria, Firmicutes/Bacteroidetes ratio, and genus Lactobacillus, Alistipes, Prevotella, Paraprevotella, and Helicobacter to be significantly associated with dry eye severity.
  • [1.2
    - Microbial communities in dry eye disease are distinct and remain distinct even with daily saline eye wash. - In dry eye disease, increased microbial diversity is a hallmark of disease.
  • [1.3] [#Short Chain Fatty Acid
    - Dry eye syndrom > Reduced SCFA has been found to alter the circadian rhythm, which in turn reduces lacrimal gland secretions.
  • [1.4
    - family #Propionibacteriaceae and the species #Corynebacterium tuberculostearicum were more abundant in DED patients compared to controls. - Both #Corynebacterium tuberculostearicum and bacteria of the family #Propionibacteriaceae are involved in inflammatory processes through the upregulation of pro-inflammatory cytokines that may be associated with DED.
  • - the conjunctiva of DED patients was decreased in genes of L-lysine biosynthesis, tetrapyrrole biosynthesis, 5-aminoimidazole ribonucleotide biosynthesis, and the super pathway of L-#Threonine biosynthesis.

References Notes


  • [1.7
MetaBiom only uses strictly necessary session cookies to give you the best possible experience on the website. By selecting "Accept essential cookies" you agree to the use of these cookies.