Lachnospiraceae ⇒ Anaerostipes {10000836}
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Definition: | Anaerostipes |
Initialisation date: | [ ] |
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Rank: | Genus |
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Domain: | Bacteria |
Zone: | [ ] |
Enzyme: | [ ] |
Function: | [ ] |
Notes:
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Shared Reference Notes
- [1.1] [#Diabetes Type 2]
- Anaerostipes is positively associated with type 2 diabetes. Similarly, in studies of type 1 diabetes and gestational diabetes, Parabacteroides was elevated compared to healthy controls. - [1.2] [#Diabetes Type 2]
- Low levels of Anaerostipes > improved glucose tolerance and reduced plasma triglyceride levels in mice - [1.3] [#Diabetes Type 1] [#Lipopolysaccharide]
- lipopolysaccharides biosynthesis in #Bacteroides MAGs (metagenome-assembled genomes) and #Sulfate reduction in Anaerostipes MAGs as functional signatures of MAGs with positive IA-association (Islets autoantibody) - [1.4] [#Multiple Sclerosis]
- Faecalibacteria, #Lachnospiraceae, and Anaerostipes produce butyrate, which acts via G-protein coupled receptors activation and histone deacetylase inhibition to suppress CNS demyelination, the main pathological feature in MS. - [1.5] [#Crohn’s disease] [#Clostridium cluster IV]
- #Roseburia, #Gemmiger, #Coprococcus, #Ruminococcus 2, #Butyricicoccus, #Dorea, #Fusicatenibacter, Anaerostipes, Clostridium IV were enriched in the healthy controls. - #Blautia, Clostridium IV, #Coprococcus, #Dorea, #Fusicatenibacter continued to significantly decrease in early and advanced CD patients, and Escherichia/Shigella and Proteus continued to significantly increase. - negative correlation between #Dorea, #Butyricicoccus, #Roseburia and gland reduce, #Roseburia and FC, #Butyricicoccus and goblet cells decreased, Parabacterodies and sex, Clostridium IV and CRP, #Dorea and ESR . - positive correlation between Escherichia/Shigella and CRP, #Ruminococcus 2 and clinical symptoms. - [1.6] [#Diabetes Type 2]
- A significant reduction of genera #Alistipes, Anaerostipes, #Ruminococcus was detected in the T2D group. - [1.7]
- #Inulin > increase genera #Blautia, Anaerostipes, and #Bifidobacterium - [1.8] [#Acute lymphoblastic leukemia]
- #Roseburia, #Dialister, #Prevotella, #Faecalibacterium and Anaerostipes showed reduced relative abundance in #Children with ALL at the time of diagnosis - [#Polysaccharide] - #Cessation of breastfeeding initiates the transition towards an #Adult-like gut microbiome composition, which is characterized by expansion of #Roseburia spp. and Anaerostipes spp., restriction of #Lactobacillus spp. and a functional shift towards an increased capacity to degrade complex polysaccharides
- [1.9] [#Bacteroides-Prevotella group]
- only #Faecalibacterium, but not #Blautia, Anaerostipes, or #Megamonas, was significantly lower in the #Hypertension group - [#Attention Deficit Hyperactivity Disorder] - higher abundance of three genera (#Agathobacter, Anaerostipes, and #Lachnospira) and decreased levels of TNF-α in the ADHD
- [1.11]
- patients with #Celiac Disease showed the abundance of #Streptococcus, #Lactobacillus, #Veillonella, and #Allisonella species, while the abundance of #Ruminococcus, #Faecalibacterium, #Blautia, #Gemmiger, and Anaerostipes was decreased. - [1.12] [#Multiple Sclerosis]
- Individuals with relapsing-remitting MS have an abundance of #Mycoplasma, #Pseudomonas, #Faecalibacterium, #Haemophilus, Anaerostipes, #Blautia, and #Dorea, while #Bacteroides, #Prevotella, #Parabacteroides, and #Adlercreutzia are relatively less common. - [1.13] [#Omega 3]
- omega-3 rich diet has been shown to result in a significant increase in #Subdoligranulum, along with other #Butyrate producers like Anaerostipes, #Coprococcus, and #Roseburia. - [#Juvenile idiopathic arthritis] [#Roseburia hominis] - In JIA > reduced Anaerostipes, #Dialister, #Lachnospira, and #Roseburia have been correlated with rheumatic clinical indices including antibodies, erythrocyte sedimentation rate (ESR) and clinical JIA disease activity score. - #Dialister, #Lachnospira, and #Roseburia (#Roseburia hominis in 0% of ABISJIA) were three of five genera reduced in ABISJIA, as well as an ASV belonging to Anaerostipes.
References Notes
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