Disease ⇒ Heart failure {40000230}

Shared Reference Notes

• [1.1] [#CVD, #Hearth attack] 
• [1.2] [#Eubacterium hallii, #Lachnospiraceae, #Ruminococcaceae] 
  - patients with HF have a decrease in #Butyrate-producing bacteria, especially, Lachnospiracea and Ruminococcacea families. - reduction of the #Butyrate-producing Eubacterium Halli and Lachnospiracea is correlated with increased inflammation, severity of disease, heart damage and mortality
• [1.3] 
  - #TMAO levels are also associated with heart failure and #Coronary artery disease. - #TMAO enhances the responsiveness of platelets to multiple agonists, promoting platelet hyperactivity and thus thrombosis and subsequent cardiovascular disease.
• [1.4] 
• [1.5] [#Atrial fibrillation] 
  - possible negative association of prevalent AF with #Bifidobacterium, and a positive relation for incident AF. - In heart failure patients, the genus #Bifidobacterium is depleted. - #Bifidobacterium has been positively correlated with ejection fraction and negatively with the cardiac stress marker N-terminal pro B-type natriuretic peptide.
• [#Atrial fibrillation] - #Enorma, #Bifidobacterium, and #Eisenbergiella were among the top associations of prevalent and incident AF. - At the genera level, the top association of prevalent AF was observed with #Enorma. - #Enorma belongs to the family of Coriobacteriaceae, which were among the core families related to heart failure

References Notes