Bacteroides ⇒ Bacteroides vulgatus {10000146}

Shared Reference Notes

• [1.1] [#Ulcerative Colitis] 
  - Elastase activity directly correlated with known proteolytic taxa, such as #Bacteroides vulgatus and high elastase activity was confirmed in Bacteroides isolates from fecal samples. - Mice colonized with or born from pre-UC colonized dams developed higher fecal proteolytic activity and an inflammatory immune tone compared with HC colonized mice.
• [1.2] [#Polycystic ovary syndrome] 
  - A dysbiotic gut microbiome from women with PCOS or Bacteroides vulgatus (positively associated with PCOS in antibiotic-treated mice) transplanted into mice induced a PCOS-like phenotype (HA, disrupted estrous cycle, decreased ovulation, ovarian cysts, and a decrease in fertility.) - Higher testosterone levels are linked with changes in the overall composition of the gut microbial community. It is unclear whether testosterone exerts an effect on gut microbes directly and/or indirectly through actions in androgen target tissues.
• [1.3] [#Crohn’s disease] 
  - Bacteroides vulgatus is both directly associated with Th17 immunity and has a higher abundance in active CD relative to non-IBD controls. - The increase of Bacteroides vulgatus abundance in active CD can induce more Th17 cells that in turn might worsen IBD inflammation.
• [#Inflamatory bowel disease] - Seven bacterial species correlated with expression levels of Th17 effector cytokines, IL-17A and IL-17F. - The seven associated species include #Ruminococcus gnavus, #Escherichia coli, #Lachnospiraceae bacterium, #Clostridium hathewayi, #Bacteroides faecis, Bacteroides vulgatus, and #Akkermansia muciniphila. All of the species were positively associated with IL-17A/ IL-17F except #Akkermansia muciniphila, suggesting these species are proinflammatory, while #Akkermansia muciniphila is anti-inflammatory.
• [1.4] [#Diabetes Type 2] 
  - TIIDM > low levels of #Roseburia inulinivorans, #Eubacterium eligens , and Bacteroides vulgatus, - All these bacteria > increase following the “good” diet and > decrease following the “bad” diet.
• [1.5] 
  - the tested consortium was composed of four butyrate producers (#Faecalibacterium prausnitzii, #Butyricicoccus pullicaecorum, #Roseburia inulinivorans, and #Anaerostipes caccae) and five propionate producers (#Roseburia inulinivorans, #Akkermansia muciniphila, Bacteroides vulgatus, #Veillonella parvula, and #Blautia obeum)
• [1.6] [#Ulcerative Colitis] [#Primary bile acids, #Secondary bile acids] 
  - colonic CD displayed a disease-severity-related association with Bacteroides vulgatus. - Compared to colonic CD, ileal CD profiles displayed increased primary and secondary bile acid levels and concomitant shifts in taxa with noted sensitivities such as #Faecalibacterium prausnitzii or affinities for bile acid-rich environments, including #Gammaproteobacteria and #Blautia sp.
• [1.7] [#Chronic fatigue syndrome, #Irritable bowel syndrome] [#Alistipes putredinis, #Anaerotruncus colihominis, #Clostridium asparagiforme, #Coprococcus catus, #Dorea formicigenerans, #Faecalibacterium prausnitzii] 
  - Nine bacterial species were selected to predict ME/CFS + IBS: F. prausnitzii, Bacteroides vulgatus, A. putredinis, C. catus, #Anaerostipes caccae, D. formicigenerans, A. colihominis and C. asparagiforme.
• [1.8] [#Anorexia nervosa] 
  - in AN > Serum #Leucine mediated the influence of B. vulgatus counts on #Glucose homeostasis.

References Notes