Disease ⇒ End-stage renal disease {40000498} Record Keys Type:Disease Parent:[ ] Definition:End-stage renal disease Details Initialisation date:[ ] Other Terms:ESRD Meta Information MedDra ID:10038435 MedDra Level:pt ICD:[ ] Category:[ ] Zone:[ ] Mechanism:[ ] Notes: [ ]Shared Reference Notes [1.1] - #TMAO is a major risk factor for cardiovascular disease, renal fibrosis and functional impairment, #Atherosclerosis, and #Colorectal cancer. [1.2] - #Nitrate treatment boosted the #Nitrate-nitrite-NO pathway, which ameliorated UUO-induced renal dysfunction and #Fibrosis in mice, represented by improved glomerular filtration and morphological structure and decreased renal collagen deposition, pro-fibrotic marker expression, and inflammation.References Notes[ ]
