MetaBiom
Microbiome & Chronic Diseases

Evidence Based Medicine
Sign in

Eggerthella ⇒ Eggerthella lenta {10000209}

Record Keys


Parent:
Definition:
Eggerthella lenta

Details


Initialisation date:
2019-06-16

Links


Meta Information


Rank:
 Species
Domain:
 Bacteria
Enzyme:[  ]
Function:
Dopamin-Degrading

Notes:


Produces meta-tyramine from Dopamin

Shared Reference Notes


  • [1.1
    - #Proanthocyanidins are biotransformed by #Adlercreutzia equolifaciens JCM 14793T, #Eubacterium sp. SDG-2, Eggerthella lenta rK3 and Eggerthella lenta CAT-1 and from the phylum actinomycetes, which belong to the phylum #Actinobacteria, through the cleavage of the C-ring and dihydroxylation reactions to produce (−)EGC, (−)-gallocatechin (GC), (±)EC and (±)-catechin (C)
  • [1.2] [#Diabetes Type 2] [#Imidazole propionate
    - Imidazole propionates (ImP), produced by several bacterial strains, including #Streptococcus mutans and Eggerthella lenta, which was found to be elevated in individuals with T2DM and impairs insulin signaling through activation of the p38γ-p62-mTORC1 pathway
  • [1.3
    - Eggerthella lenta JCM 9979 was shown to facilitate the C-ring cleavage of #Epicatechins and #Catechins and the subsequent 4’-dehydroxylation to produce different intermediate metabolites.

References Notes


  • (1) [1.15

Common References