Sign ⇒ Sarcopenia {40000580}
| Type: | Disease, Sign |
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| Parent: | [ ] |
| Definition: | Sarcopenia |
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| Other Terms: | [ ] |
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| MedDra Level: | [ ] |
| ICD: | [ ] |
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Notes:
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Shared Reference Notes
- [1.1]
- The genera Lachnospira, Fusicantenibacter, Roseburia, Eubacterium, and Lachnoclostridium—known #Butyrate producers—were significantly less abundant in Case and preCase subjects while Lactobacillus was more abundant. - Functional pathways underrepresented in Case subjects included numerous transporters and phenylalanine, tyrosine, and tryptophan biosynthesis suggesting that protein processing and nutrient transport may be impaired. - -#Lipopolysaccharide biosynthesis was overrepresented in Case and PreCase subjects suggesting that sarcopenia is associated with a pro-inflammatory metagenome.
- [1.2] [#Faecalibacterium prausnitzii] [#Aging]
- older subjects with physical #Frailty and sarcopenia > Lower abundance of F. prausnitzii, as well as members of the #Clostridiales class including #Eubacterium and #Roseburia genera.
References Notes
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