Microbiome & Chronic Diseases

Evidence Based Medicine
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Sign ⇒ Sarcopenia {40000580}

Record Keys

Disease, Sign
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Shared Reference Notes

  • [1.1
    - The genera Lachnospira, Fusicantenibacter, Roseburia, Eubacterium, and Lachnoclostridium—known #Butyrate producers—were significantly less abundant in Case and preCase subjects while Lactobacillus was more abundant. - Functional pathways underrepresented in Case subjects included numerous transporters and phenylalanine, tyrosine, and tryptophan biosynthesis suggesting that protein processing and nutrient transport may be impaired.
  • -#Lipopolysaccharide biosynthesis was overrepresented in Case and PreCase subjects suggesting that sarcopenia is associated with a pro-inflammatory metagenome.
  • [1.2] [#Faecalibacterium prausnitzii] [#Aging
    - older subjects with physical #Frailty and sarcopenia > Lower abundance of F. prausnitzii, as well as members of the #Clostridiales class including #Eubacterium and #Roseburia genera.

References Notes

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