Osteopontin {90000606} Record Keys Parent:[ ] Definition:Osteopontin Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] - OPN could reduce the colonization of #Lactobacillus in the intestine of mice and promote the abundance of #Dorea, which could further regulate metabolic disorders [#Eubacterium limosum] - At 3 months, OPN was positively correlated with E. limosum, which can produce #Butyrate along with #Acetate, as the main fertilization end-product from #Methanol. [#Human breast milk] - the breast milk OPN content declined at 3 months, we suggest that early breast milk OPN plays a more important role in regulating the gut microbiota. [#Parabacteroides distasonis] [#Human breast milk, #Infants] - #Lactalbumin at 42 days, > positively correlated with P. distasonis. - #Lactalbumin have pointed to improved early immunity and intestinal mucosal barrier. - #Lactalbumin and OPN might jointly affect P. distasonis early in life to regulate infant immunity. [#Parabacteroides distasonis] [#Human breast milk] - the breast milk OPN content was positively correlated with the abundance of P. distasonis > maintaining and protecting intestinal health and the gut barrier. - the effects of early breast milk OPN may last for several months, as there was still a positive correlation between the breast milk OPN content at 42 days and P. distasonis at 3 monthsReferences Notes[ ]
